Binding of Isaac: Rebirth Wiki

Added in Afterbirth †

Ouroboros Worm is a trinket added in The Binding of Isaac: Afterbirth †.


  • Tears travel in a large spiral pattern.
  • Grants spectral tears.
  • Removed in Repentance +4.0 range.
  • +2.0 tear height.
  • A luck-based chance for a homing shot, reaching 100% at 9 luck.
    • The homing shots are not different in appearance.
    • The homing does not override the spiral pattern, making them still unreliable.


  • Added in RepentanceAquarius Aquarius: Creep has a chance to be homing.
  • Dr. Fetus Dr. Fetus: Since the bombs don't follow the spiral pattern, only the extra range, spectral bombs, and chance for a homing bomb apply.
  • Tractor Beam Tractor Beam: The tears follow a straight path, ignoring the spiral pattern; the tears also stall at a specific point, giving a greater chance to land tears.


  • Removed in Repentance Azazel Azazel: Increases the range of his short-ranged Brimstone. No homing chance.
    • Added in Repentance His Brimstone now spins.
  • Removed in Repentance Brimstone Brimstone: Overrides Ouroboros Worm.
    • Added in Repentance The Brimstone laser is shot in a spiral pattern. Homing does take effect, but is hardly noticeable.
  • The Ludovico Technique The Ludovico Technique: The tear spirals around in a difficult to control manner, with the added homing chance further complicating things.
  • Removed in RepentanceMom's Knife Mom's Knife: Overrides Ouroboros Worm.
    • Added in Repentance Works as intended. The homing, however, is questionable.
  • Proptosis Proptosis: The curious pattern allows dealing full damage from a safer range.
  • Tainted Azazel Tainted Azazel: His Brimstone laser is shot in a spiral pattern. Homing does take effect, but is hardly noticeable.
  • Removed in RepentanceTech X Tech X: Overrides Ouroboros Worm.
    • Added in Repentance Tech X now inherits the homing chance benefit, without being affected by the pattern.
  • Removed in RepentanceTechnology Technology: Grants spectral tears without a change in pattern or a chance of homing shots.
    • Added in Repentance The tech laser is now affected by the pattern. The homing DOES take affect, but it's fairly hard to notice.

In-game Footage[]


  • This trinket is a reference to Øuroboros, which was a prototype of the game "The End is Nigh" by Edmund McMillen and Tyler Glaiel.
  • The Ouroboros is an ancient symbol, showing a serpent or dragon eating its tail.