Binding of Isaac: Rebirth Wiki
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Nerve Endings are purely static enemies with no proactive means of dealing damage. They can deal contact damage, but only if Isaac somehow walks directly into them.

Variations[]

Nerve Ending 2[]

Added in Afterbirth †

Nerve Ending 2s are stationary enemies which will swipe at Isaac if he gets too close. This attack can only connect if Isaac is horizontal with it, but will deal contact damage in any case if Isaac walks into them. Otherwise, they have no means of attacking and are generally harmless.

Notes[]

  • Nerve Ending 2 can never replace regular Nerve Endings next to doors.
  • If Nerve Ending 2s aren't unlocked yet, they are replaced by Nerve Endings.

Trivia[]

  • It's possible that the Nerve Ending is a giant axon, an electrical impulse terminal for nerve cells, which could explain its name.


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