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Trinket icon
"Never again!"
Table dividing line 1.png
Trinket ID
Added in Afterbirth

NO! is a trinket added in the The Binding of Isaac: Afterbirth expansion.

Effect[edit | edit source]

  • Prevents activated collectibles from being generated, if possible, from all item pools while this trinket is being held.
  • Added in Repentance If multiple copies are held, rerolls items with quality 0.

Notes[edit | edit source]

  • Activated items will start appearing again once the item pool's non-activated items are exhausted or become scarce.
  • When the trinket is dropped, the item generation mechanics go back to normal, and active items will be generated normally again.
  • Removed in Repentance Does not affect Libraries until all the books have been collected, as the library pool consists only of activated items.
  • Fixed boss drops and machines are not affected by NO!:
  • In runs where many items have been collected/rerolled, the trinket can function as a sort of warning to the player that an item pool will soon be exhausted if activated items begin to show up.
  • Added in Repentance15►Book of Virtues Book of Virtues will not be removed from Libraries while this trinket is held.

In-game Footage[edit | edit source]

Gallery[edit | edit source]

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