Binding of Isaac: Rebirth Wiki

Mysterious Liquid is a passive item.


  • Tears leave a small, short-lasting pool of creep upon hitting an enemy or when their range is depleted.
    • The creep deals 1 damage per tick or 30 damage per second.
    • Added in Repentance The creep can deal up to 25 damage.
    • Multiple creeps can inflict damage on an enemy simultaneously.


  • Added in Afterbirth †Compound Fracture Compound Fracture / Cricket's Body Cricket's Body / The Parasite The Parasite: Each split tear leaves a creep, creating lots of creeps.
  • Added in AfterbirthExplosivo Explosivo: Leaves an explosion-sized creep whenever the Explosivo tear goes off.
  • Added in Afterbirth †Flat Stone Flat Stone: Every time tears bounce, creep spawns.
  • The Ludovico Technique The Ludovico Technique: Spawns creep trail under the tear on a constant time interval.
  • Mom's Knife Mom's Knife: Spawns a line of creep behind the knife as it shoots towards enemies, each one left on random time interval.
  • Added in RepentanceSpirit Sword Spirit Sword: The projectiles from the sword spawn creeps, sword attacks do not.
  • Added in Afterbirth †Tech.5 Tech.5: The lasers spawn creeps always when it hits obstacles and occasionally on enemies.
  • Added in Afterbirth †Technology 2 Technology 2: The lasers rapidly spawn creeps on hitting both obstacles and enemies.
  • Added in AfterbirthTech X Tech X: The laser rings spawn creeps when it hits enemies on a constant time interval.
  • Added in Afterbirth †Trisagion Trisagion: The blasts leave long trails of creeps, and a creep for each damaging tick. Since the effect stacks, they cause massive damage.


In-game Footage[]


PC ABP0 1DJA (Treasure Room adjacent to spawn)

PC QXAX ZJYL (Treasure Room adjacent to spawn)

PC Added in Repentance P46B THHA (Treasure Room adjacent to spawn)

PS4 V8ZG HD31 (First floor Treasure Room)

Vita 2J39 EANS (Treasure Room adjacent to spawn)

Switch HLL1 RW2R (Treasure Room adjacent to spawn)