Mutant Spider

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Mutant   Spider
Item icon
Item altar
"Quad shot"
Table dividing line 1.png
Item ID
5.100.153
Character Appearance
Character appearance
Table dividing line 2.png
Table dividing line 3.png
Collection Grid
Removed in Afterbirth(page 2, column 10, row 5)
Added in Afterbirth(page 2, column 10, row 2)

Mutant Spider is a special passive item.

Effects[edit | edit source]

  • Isaac fires a spread of four tears at once.
  • Tears down: (Delay * 2.1) + 3
  • Added in Afterbirth † This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.

Notes[edit | edit source]

  • The maximum amount of tears per volley that can be reached by combining and/or duplicating 15►20/20 20/20, 15►The Inner Eye The Inner Eye, Mutant Spider and Added in Afterbirth15►The Wiz The Wiz is 16, or 20 with the Keeper.

Synergies[edit | edit source]

  • 15►Cursed Eye Cursed Eye: Fires 4 rows of 4 tears, resulting in 16 tears.
  • Added in Afterbirth15►Diplopia Diplopia: Effects stack, results in 8 tears being shot with no further decrease in fire rate.
  • 15►Doctor's Remote Doctor's Remote/15►Epic Fetus Epic Fetus: Replaces the single missile strike with a barrage of four consecutive missiles.
  • Added in Afterbirth 15►The Inner Eye The Inner Eye: Shoots 7 tears with no further decrease in fire rate.
  • 15►The Ludovico Technique The Ludovico Technique: The tear gains three orbiting tears.
  • 15►Monstro's Lung Monstro's Lung: Adds 7 tears to barrage with a significant increase in tear delay, which is very bad.
  • 15►Polyphemus Polyphemus: Tear rate is not lowered further. Damage is increased by a flat +5 instead of normal Polyphemus boost.
  • 15►Technology 2 Technology 2: The laser is not affected by Mutant Spider.
  • Added in Afterbirth15►Tractor Beam Tractor Beam: All tears are fired along the beam, but some may be hard to see as they overlap each other.
  • Added in Afterbirth15►The Wiz The Wiz: Four shots are fired in each direction.

Interactions[edit | edit source]

  • 15►20/20 20/20: Overridden by Mutant Spider.
    • Added in AfterbirthRemoved in Repentance Shoots 6 tears instead of 4.
    • Added in Repentance Shoots 5 tears instead of 4.
  • Added in Afterbirth † The Forgotten: Quadruples bones thrown and swung. Significant increase in tear delay.
  • Added in Afterbirth Keeper: Fires 7 tears with significantly increased tear delay.
  • Added in Afterbirth15►Kidney Stone Kidney Stone: Increase number of tears in tear barrage; however, only fires one stone.
  • 15►Loki's Horns Loki's Horns: Only occasionally fires one tear in the other three directions.
  • 15►Mom's Eye Mom's Eye: Only occasionally fires one tear out of the back of Isaac's head.
    • Added in Afterbirth † Fires three shots diagonally out of each eye.
  • 15►Sad Bombs Sad Bombs: Does not affect the number of tears when bombs explode.
  • Added in Afterbirth †15►Varicose Veins Varicose Veins: No effect on number of tears when taking damage.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

PC AZ6W Y26Y (Treasure Room adjacent to spawn)

PC TJXE 4V96 (Treasure Room adjacent to spawn)

PC GFZN B8DP (First floor Treasure Room)

PC Added in Afterbirth 007A C1TS (Treasure Room adjacent to spawn)

PC Normal and hard modes only Added in Afterbirth BX4E YVR0 (Treasure Room adjacent to spawn)

PC Added in Afterbirth 46XR GGB4 (Treasure Room adjacent to spawn)

PS4 BPJS S7WT (Treasure Room adjacent to spawn)

PS4 GALT H2PG (Treasure Room adjacent to spawn)

Vita S37R YZKY (First floor Treasure Room)

3DS MYNT 04LF (Treasure Room adjacent to spawn)

3DS HW2X X7V4 (Treasure Room adjacent to spawn)

Switch Greed mode only Y4SW L1YF (First Golden Treasure Room)

Switch Greedier mode only VSG9 BYPQ (First Golden Treasure Room)

Switch Added in Afterbirth 1B8Y 37ZS (Treasure Room adjacent to spawn)

Switch Normal mode only Added in Afterbirth NDAV 7AY6 (Treasure Room adjacent to spawn)


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