Music

The music in The Binding of Isaac: Rebirth, Afterbirth, Afterbirth †, and Repentance was created by Ridiculon. These soundtracks can be purchased on Steam and on Ridiculon's Bandcamp page, as well as being available on Spotify, containing 32, 9, 4, and 20 tracks, respectively. Not all tracks heard in-game are included in the OST releases, and some tracks in the OST do not appear in-game or go unused.

Most main floor tracks have a heavier variant that plays when enough enemies or bosses are in the room. In the OST, these variants are generally heard in each song’s second half. What instrument is added is listed next to each track's name in square brackets.

The Binding of Isaac: Rebirth[]

Bandcamp title	Spotify title (if different)	Plays where?	Internal filename
Genesis 22:10 (Title)	N/A	Title Screen	title screen
Diptera Sonata [Guitar]		Basement	diptera sonata(basement)
Crusade (Basic Boss Fight)		Most boss fights	basic boss fight
Sodden Hollow (Caves) [Bass guitar]		Caves	the caves
The Forgotten (Secret Room)		Secret Room; Super Secret Room	secret to everyone
Abyss (The Depths) [Ambient sounds]		Depths	the depths
Matricide (Mom Fight)		Mom fight	mom fight
The Calm		After defeating most bosses; before starting a Challenge Room	the calm
Viscera (Womb) [Drums]		Womb; Utero	the womb chapter four
Ventricide (Womb Fight)		Mom's Heart	womb fight
Acceptance (You Died)		Death screen	you died
Anima Vendit (Deal With the Devil)		Devil Room; Satan fight before The Fallen spawns	deal with the devil
Duress (Sheol) [Drums]		Sheol	sheol
Hericide (Satan Fight)		Satan fight after defeating The Fallen	satan fight
Murmur of the Harvestman (Store)		Shop	store loop
Empty Vessels (Angel Room)		Angel Room	angel room
Everlasting Hymn (Cathedral) [Backing choir]		Cathedral	cathedral chant
Infanticide (Isaac Fight)		Isaac fight	isaac fight
Ambush	Same name, but at the end of the album	Challenge Room; Boss Rush	ambush
Tome of Knowledge (Library)	N/A	Library	library
Periculum (The Cellar) [Guitar]		Cellar	the cellar alt
Capitulus Calvaria (Catacombs) [Guitar]		Catacombs	catacombs
When Blood Dries (Necropolis) [Guitar]		Necropolis	necropolis
Sketches of Pain (Chest Room) [Guitar]		Chest	chest room chapter 6
Ascension (Chest Fight)		??? Fight	chest fight
Devoid (___________)	Devoid (Dark Room)	Dark Room	dark room alt chapter 6
The Fallen Angel (_____________)	The Fallen Angel (Dark Room Fight)	The Lamb fight	dark room fight
Tribute (Credits Roll)	Tribute (Credits)	Credits	credits roll
Genesis 13:37 (Retro Beats)	N/A	Arcade	retro beats 8-6-14
Hush (Jesus Loves Uke)	N/A	Credits after beating Mom's Heart for the 10th time	jesus loves uke
Descensum (BONUS)	Descensum (Bonus Track)	(not heard in-game)	(n/a)
He's the Number One (BONUS)	He's the Number One (Bonus Track)	(not heard in-game)	(n/a)

The Binding of Isaac: Afterbirth[]

Bandcamp title	Spotify title (if different)	Plays where?	Internal filename
ReGenesis	Regenesis (Title)	Title Screen	regenesis (loop) v3
Cerebrum Dispersio (Boss Alt)	N/A	Chance to replace Crusade	cerebrum dispersio (boss alt) loop
Cicatrix [Drums]	Cicatrix (Scarred Womb)	Scarred Womb	cicatrix (scarred womb) loop
Fundamentum [Guitar]	Fundamentum (Burning Basement)	Burning Basement	burning basement loop
Kave Diluvii [Guitar]	Kave Diluvii (Flooded Caves)	Flooded Caves	kave diluvii (flooded caves) loop
Nativitate [Guitar]	Nativitate (Dead Womb)	???	nativitate (dead womb floor) loop
Morituros	Morituros (Hush Fight)	Hush fight	morituros (dead womb boss) loop
Pulso Profundum [Drums]	Pulso Profundum (Dank Depths)	Dank Depths	pulso profundum (dank depths ) loop
Chorus Mortis (Alt Title Theme)	Chorus Mortis (Ultra Greed)	Ultra Greed fight	chorus mortis (punk credit) loop

The Binding of Isaac: Afterbirth †[]

Bandcamp title	Spotify title (if different)	Plays where?	Internal filename
Terminus ( ________ )	Terminus	The Void	void
Delirium	N/A	Delirium fight	delirium fight
Sepulcrum	N/A	Final Ending / Ending 20	the_void_ending
Ante Lucem (BONUS)	Ante Lucem	(not heard in-game)	(n/a)

The Binding of Isaac: Repentance[]

Bandcamp title	Spotify title (if different)	Plays where?	Internal filename
Genesis Retake Light	N/A	Title Screen	genesis retake light loop
River of Despair (Downpour) [Heavier instrumentation]		Downpour	downpour
Juggernaut (Boss Alt)		Boss fights on Repentance alt floors	boss alt
Fissure (Mines) [Heavier instrumentation]		Mines	mines
Super Secret Room		Super Secret Room	secret room alt
Walls of Denial (Mausoleum) [Heavier instrumentation]		Mausoleum	mausoleum
Dread (The Calm Twisted)		After defeating the Mausoleum variant of Mom's Heart	the calm twisted v4 loop
Carrion (Corpse) [Guitar]		Corpse	corpse
Morticide (Corpse Fight)		Mother fight	mother_boss_v6
Caesarian (Utero) [Guitar]		Utero	utero
Armageddon (Boss Rush)		Boss Rush	boss rush
StarGazer (Planetarium)	Stargazer (Planetarium)	Planetarium	planetarium
Night Soil (Dross) [Heavier instrumentation]	N/A	Dross	sewer
Absentia (Ashpit) [Heavier instrumentation]		Ashpit	ash pit
Morning Star (Gehenna) [Heavier instrumentation]		Gehenna	gehenna
Bygone		Ultra Secret Room	super secret room loop (sic)
Home [Mom's shouts]		Home	echoes of mom
Living In The Light		Dogma fight	static boss light v2
Revelations 13-1		The Beast fight	the_end_beast
Genesis Retake Dark		Tainted character select	genesis retake twisted loop
(Not Included)		Knife Piece 2 area	vast empty chasm
		Mother's Shadow chase	chased by death v3
		Ascent	genesis ii reverse
		Home at night	echoes of mom twisted v2
		Death Certificate area	echoes reverse
		Final Ending	end end end vo
		Replaces Jesus Loves Uke after unlocking Dead God	jesus loves viggo v3

Trivia[]

Besides the music listed here, Ridiculon have released two unofficial albums; The Binding of Isaac - Lullabies (which has a colon instead of a hyphen on Spotify) and The Binding of Isaac: Mutations.
Ridiculon have also released a single titled The Binding of Christmas, though this is only available on Bandcamp.
Devoid and The Fallen Angel's descriptions are simply a line of underscores on Bandcamp, while they have real descriptions in the Spotify release. This was likely done to prevent spoilers, as Dark Room was new to Rebirth and not present in Flash Isaac. Terminus also has these underscores, but the description is entirely absent in the Spotify release.
The Legend of Bum-Bo, a Binding of Isaac spinoff, has a title theme that sounds similar to and shares a name with Rebirth’s title theme.
In an interview on Steam, Ridiculon producer Jon Evans listed the OST songs he is most proud of: “‘Sodden Hollow’ for its dripping groove. ‘Sheol’ for even being allowed to be so terrifying in a game OST. ‘Delirium’ for its dank heaviness.” He also points out that “every track we’ve written for Repentance is our fave.”
???’s and Home’s music both have “heavy” layers that normally cannot be heard in-game since their respective floors do not contain enemies.
- ???’s theme can now be heard in-game by various methods, such as using Red Key in ???.
The filename of Jesus Loves Viggo alludes to Viggo Bossi, Isaac’s voice actor, who sings on the track.