Binding of Isaac: Rebirth Wiki

Added in Repentance

Mucormycosis is a passive item added in The Binding of Isaac: Repentance.


  • Gives Isaac a 25% chance to shoot a spore that, in addition to dealing damage, will stick to enemies.
    • The chance is not affected by Luck.[1]
  • Spores will explode 2.5 seconds after sticking to an enemy, dealing 5 damage to and poisoning nearby enemies and firing four more spores in a cross pattern.
    • Spores produced from Isaac's spores have homing.
    • The spore effects will not damage Isaac.
  • This item belongs to the Fun Guy set. Collecting three items from this set will transform Isaac into a walking mushroom.


  • Items such as Brimstone Brimstone and Technology 2 Technology 2 will apply spores to enemies as well, despite the absence of tears.


  • Gigante Bean Gigante Bean: Spore explosions count as farts, and as such are increased in size.
  • Godhead Godhead: Godhead's aura expands as the spore tear grows on enemies.
  • Lodestone Lodestone: Magnetized enemies draw other enemies to them, greatly increasing the chance that spores spread to other enemies.
  • Lost Contact Lost Contact: Stuck tears will block projectiles shot by attached enemies, crippling or even stopping their ability to shoot projectiles entirely.



  • Mucormycosis is a fungal infection caused by fungi in the order Mucorales.
  • In Antibirth, this item had a similar effect to that of Contagion Contagion.