Binding of Isaac: Rebirth Wiki
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Mr. Fred is a boss that can appear:

Behavior[ | ]

Mr. Fred stays stationary in the middle of a 1x2 or 2x1 room and performs the following attacks:

  • Breaks the chain of 1 of the 4 HomunculusHomunculi that accompany him at the beginning of the fight.
    • Unlike other Homounculi, the ones spawned with Mr. Fred can not break free on their own and can only be unleashed by this attack.
  • Shoots 4 large long-range blood projectiles in the cardinal directions. These tears leave Red Creep and will burst at the end of their range into a larger pool of Creep.
  • Burrows underground briefly and pops back up in his original position, firing eight projectiles in all directions.
  • Spawns a FredFred on his position, which immediately burrows underground.

Mr. Fred deals a whole heart of contact damage.

Gallery[ | ]

Trivia[ | ]

  • Mr. Fred is the boss version of the Freds.
  • Mr. Fred resembles a large baby with a medical condition Harlequin Ichthyosis. He could, therefore, be a giant Harlequin Baby.
  • (in Rebirth and Afterbirth) Unlike other bosses, Mr. Fred disappears upon death instead of exploding into blood.
  • (in Afterbirth † and Repentance) Similar to Delirium's room, if Mr. Fred spawns in The VoidThe Void, his room will be seen in the map as a 1x1 room.
  • Mr. Fred's boss art shows the ground around him to be grey, instead of a fleshy red.


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