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Monster Manual is an activated item.
Effects[]
When used, a random familiar will be spawned from the following:
???'s Only Friend- Angry Fly
- Ball of Bandages
- BBF
- Big Chubby
- Big Fan
- Bloodshot Eye
- Bob's Brain
- Boiled Baby
- Bot Fly
- Brother Bobby
- Cube of Meat
- Demon Baby
- Distant Admiration
- Dry Baby
- Farting Baby
- Fate's Reward
- Forever Alone
- Freezer Baby
- Friend Zone
- Fruity Plum
- Gemini
- Guardian Angel
- Halo of Flies
- Headless Baby
- Hushy
- Incubus
- Juicy Sack
- Leech
- Lil Abaddon
- Lil Brimstone
- Lil Delirium
- Lil Gurdy
- Lil Haunt
- Lil Loki
- Lil Monstro
- Lil Spewer
- Little Chubby
- Little Gish
- Little Steven
- Lost Fly
- The Peeper
- Psy Fly
- Robo-Baby
- Robo-Baby 2.0
- Rotten Baby
- Seraphim
- Shade
- Sissy Longlegs
- Sister Maggy
- Smart Fly
- Succubus
- Sworn Protector
- Tinytoma
- Twisted Pair
- Familiars spawned by Monster Manual last for the current room.
- Familiars spawned by Monster Manual last for the rest of the floor.
- Familiars generated by Monster Manual do not contribute toward transformations.
- This item belongs to the Bookworm set. Collecting three items from this set will transform Isaac into Bookworm.
Familiars spawned by Monster Manual last for the current room.
Notes[]
- It can spawn familiars not yet unlocked.
- If Cube of Meat or Ball of Bandages are spawned and Isaac already has either of those items, the level of these items will increase for the current room floor.
- Using Monster Manual is a good method to unlock achievements related to Super Meat Boy and Super Bandage Girl.
- Using Monster Manual and enough Lil' Batteries, Super Meat Boy and Super Bandage Girl can both be achieved in the same run.
- If Isaac does not already have the Cube of Meat or Ball of Bandages, Monster Manual can spawn a level 2 Cube of Meat or Ball of Bandages in one use.
- Using Monster Manual and enough
- Mongo Baby will not copy familiars spawned by Monster Manual.
- Familiars spawned by Monster Manual cannot be rerolled into other items by D4 or D100.
- Box of Friends will not duplicate familiars spawned by Monster Manual.
- Tinytoma orbitals will persist between floors until they are all destroyed. They will not respawn outside of the floor they were generated in.
- The familiars summoned by Monster Manual are items with a
monstermanualitem tag. - Tainted Lazarus: If dead Tainted Lazarus has used Monster Manual, but living Tainted Lazarus progresses to the next floor(or vice versa), familiars from the previous floor are not removed. Upon exiting the game, or moving to the next floor as either character, any familiars retained this way are lost, meaning familiars cant be kept at most 1 extra floor.
Synergies[]
- Book of Virtues: Spawns wisps in the inner ring. The given wisps function similarly to familiars given by Buddy in a Box.
Interactions[]
- Sacrificial Altar: Summoned familiars can be sacrificed since they persist for the entire floor, even if Monster Manual isn't currently being held.
In-game Footage[]
Trivia[]
- In the original The Binding of Isaac, due to a typing error this item was called "Monster Manuel". This has been corrected for Rebirth.
- Monster Manual may sometimes display the misspelled name when picked up.
- Monster Manual is a direct reference to Dungeons & Dragons. Its appearance in the game closely resembles the Advanced Dungeons & Dragons First Edition Monster Manual.
- The item being in the Devil Room pool is likely a reference to the moral panic surrounding the game in the 1980s.
Gallery[]
3DS The icon of Monster Manual as seen on the lower 3DS screen
Monster Manual's splash image which appears when it's activated.
Seeds[]
PC HGN1 GBFC (
Treasure Room adjacent to spawn)
PC A6V2 BD1M ( Treasure Room adjacent to spawn)
PC RPFQ NXGG ( Treasure Room adjacent to spawn)
PC 
PSXL 8WRV ( Treasure Room adjacent to spawn)
PC 
KSVH 8CTT ( Treasure Room adjacent to spawn)
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