Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Afterbirth

Mom's Box is an activated item added in Afterbirth.


  • Upon activation, drops a random trinket on the ground.
  • +1 luck while held.
  • While held, doubles the effect of eligible trinkets.
    • Added in RepentanceAbout half of all trinkets – 48% – are not eligible for doubling.
    • Added in RepentanceThis effect stacks additively with Golden Trinkets, rather than multiplicatively. Holding Mom's Box with a Golden Trinket will cause it to have triple the regular effect, rather than quadruple.
  • Added in RepentanceThis item belongs to the Yes Mother? set. Collecting three items from this set will transform Isaac into his mother.


  • Mom's Box can be used to unlock 15►Mom's Contacts Mom's Contacts when combined with two other Mom items.
  • If absorbed by Added in Afterbirth †15►Void Void, the trinket doubling effect will be lost.
  • Added in Afterbirth † Trinkets absorbed by 15►Smelter Smelter, 15►Marbles Marbles, or Gulp! will also be doubled.

No Effect[]

These trinkets are not affected by Mom's Box, listed in alphabetical order.

In-game Footage[]


  • The item description possibly is a reference to the film Seven where the climax of the film involves the protagonist asking the question over and over again "What's in the box?".
  • Added in Repentance The item strongly resembles the chest found in Mom's room in Home.
  • Added in Repentance This item is used in Pica Run (challenge #41).

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