Binding of Isaac: Rebirth Wiki

(except in Rebirth)

Mom's Box is an activated item added in The Binding of Isaac: Afterbirth.

Effects[ | ]

  • Increases luck by 1 and doubles the effects of certain trinkets while held. When used, drops a random trinket on the ground.
  • (in Repentance) This item belongs to the Yes Mother?Yes Mother? set. Collecting three items from this set will transform Isaac into his mother.

Notes[ | ]

  • Most trinkets are not affected. (in Repentance) Of the 188 trinkets in Repentance, only 72 have a doubled effect.
  • (in Repentance) This effect stacks additively with Golden Trinket Golden Trinkets; holding one with Mom's Box will cause applicable trinkets to have triple the regular effect.
  • Holding a second Mom's Box by using (in Afterbirth † and Repentance)Collectible Schoolbag iconSchoolbag only increases luck, the effects of trinkets are not affected further.

Synergies[ | ]

  • (in Repentance)Collectible Book of Virtues iconBook of Virtues: Spawns a normal wisp with no unique effect.
  • (in Afterbirth † and Repentance) Gulp! Pill / Collectible Marbles iconMarbles / Collectible Smelter iconSmelter: Trinket effects are still doubled when permanently applied to Isaac.
  • (in Repentance)Broken RemoteBroken Remote: Triggers the Collectible Teleport 2.0 iconTeleport 2.0 effect whenever an activated item is used.
  • (in Repentance)Crystal KeyCrystal Key: Increases the chance of red rooms spawning.
  • (in Repentance)NO!NO!: Prevents items with quality 0 from appearing.
  • (in Repentance)Rosary BeadRosary Bead: Adds 4 Rosaries to all item pools. Upon picking up a Rosary, the effect will end.
  • TickTick: Boss' health will be reduced by 30%. Having the Tick also be golden does not further decrease boss' health.
  • (in Repentance)Hook WormHook Worm / Ring WormRing Worm / Wiggle WormWiggle Worm: In addition to the further stats increase, they have an increased effect on your tear trajectory.

Interactions[ | ]

  • (in Repentance)Mother's KissMother's Kiss: Grants double the heart containers but only one of them is filled.
  • (in Afterbirth † and Repentance)Collectible Void iconVoid: Passive effects of Mom's Box are lost if absorbed.

No Effect[ | ]

These trinkets are not affected by Mom's Box.

Unlockable Achievements[ | ]

Trivia[ | ]

  • The item description possibly is a reference to the film Seven (1995) where the climax of the film involves the protagonist asking the question over and over again "What's in the box?".
  • (in Repentance) The item strongly resembles the chest found in Mom's room in HomeHome.
  • (in Repentance) This item is used in (in Repentance) Pica Run (challenge #41).