Binding of Isaac: Rebirth Wiki

Added in Afterbirth †

Metronome is an unlockable activated item added in The Binding of Isaac: Afterbirth †.


  • Grants a random item's effect for the current room.


  • Beware using this as The Lost The Lost, as it can trigger self-harm items and kill him.
  • Using this item multiple times in the same room will replace the previous item with a new one.
  • Metronome cannot grant the effects of itself, Glowing Hour Glass Glowing Hour Glass, Plan C Plan C, Clicker Clicker, or Added in RepentanceR Key R Key.
  • Keep in mind that you can trigger items you haven't unlocked yet, which means you could trigger the effect of items like Added in RepentanceDeath Certificate Death Certificate without having to go through the trouble of unlocking them.
  • If Metronome triggers the effect of Added in RepentanceGenesis Genesis, it will disappear from the active slot, just as with the real item.
  • Metronome has a reduced chance of activating Added in RepentanceGenesis Genesis or Added in RepentanceDeath Certificate Death Certificate.


  • Added in RepentanceBook of Virtues Book of Virtues: Spawns a wisp based on the item that Metronome chooses. For example, if Metronome chooses Spirit Sword Spirit Sword, the spawned wisp is a sword that fires sword projectiles.


  • Blanket Blanket / Holy Card Holy Card / Holy Mantle Holy Mantle / Wooden Cross Wooden Cross: if Metronome is used while the shield is active, any stat changes or familiars/orbitals generated from Metronome will persist between rooms until Metronome is used again or replaced with another active item. Items that modify your stats and have other additional effects will keep the stats but the effect will be gone after leaving the room. For example, the tears down applied from The Inner Eye The Inner Eye will persist between rooms, but Isaac will not shoot three tears at once.
  • Car Battery Car Battery: Metronome is activated twice at once as expected, but the item chosen for the first activation is shown raised above Isaac's head, instead of the second one that actually remains active.

Specific Item Effects[]

In-game Footage[]


  • The name, pickup quote, and effect of this item are a reference to the move 'Metronome' from the Pokémon franchise.
  • This item works similarly to the item Dead Sea Scrolls Dead Sea Scrolls.


Bug Bug! PC It is possible for this item to use an item that can teleport one to the I AM ERROR room. During the Mother Boss fight, this can happen. Using the trapdoor causes the game to crash.
Bug Bug! PC It is possible for this item to give an indefinite Breath of Life Breath of Life effect that persists throughout rooms, eventually killing the player.
Bug Bug! PC If Added in RepentanceUrn of Souls Urn of Souls is activated through Metronome, it won't shoot fire and Isaac could get stuck with the urn in his hands unable to shoot tears. You can fix this by exiting and continuing the run, restarting the room without the urn and without Metronome charges.
Bug Bug! PC Using Metronome in the Cantripped! challenge can cause the game to crash.