Mega Blast

Mega Blast is an unlockable activated item added in The Binding of Isaac: Afterbirth.

Effects[ | ]

Picking up a Lil' Battery with this item will add 3 to its charge, meaning that 4 batteries are required to fully recharge the item.
- A Charged Key will only add 3 charges.
  - Lil' Battery and Charged Key add 6 charges instead of 3.
- Picking up a Mega Battery will fully charge it twice.
Using a 48 Hour Energy pill with this item will fully charge it.
Mega Blast has an 80% decreased item pool weight, making it less likely to appear than other collectibles.
To unlock Mega Blast, Mega Satan must be defeated with all 13 characters.
- Requires defeating Mega Satan as all 15 characters (Now including Apollyon and The Forgotten).
  - Requires defeating Mega Satan as all 17 non-tainted characters. (Now including Bethany and Jacob and Esau)
It is not recommended to use Mega Blast in fight with The Beast, because its beam forces you into obstacles on the level.
- This can be mitigated to a degree with Anima Sola, especially with a Car Battery which doubles the Anima Sola's length. The Beast won't be able to spawn obstacles while chained.

All synergies and interactions pertaining to Brimstone pertain to Mega Blast, with the following exceptions and additions:

4.5 Volt: Item will gain charges for dealing damage, which is especially effective when fighting bosses with large health pool.
Book of Virtues: Spawns red wisps on the middle ring that utilize a miniature Brimstone as their weapon, which requires charging and releasing as usual. Lasers can hit up to 8 times for a total of 24 damage. If Mega Blast is being used, the wisps will continuously fire their laser outward rather than in the direction Mega Blast is firing.
Hemoptysis: Enemies hit by the sneeze will gain a curse that increases the damage the beam deals to 10x and +3 flat damage (instead of just 5x). Enemies who die to the beam under the curse will damage and spread the curse to nearby enemies. The sneeze can be activated while Mega Blast is firing.
Schoolbag: Beam will continue to fire when switching to another active item. Other active items can be used while the beam is firing.
- If Glowing Hourglass is activated while under the effect of Mega Blast, as long as you hadn't yet activated Mega Blast in the previously visited room, you will keep the Megablast effect while keeping your Mega Blast fully Charged.

Familiars which copy Isaac's tears fire normal tears while Mega Blast is in use.

Mega Blast's collectible sprite is called 'Mega Satan's Breath' in the game files, which may be its initial name.

Bug!	If the player continues a run that was exited while Mega Blast was active, Isaac will retain the costume and animation of Mega Blast until the item is used again, but no beam will appear.

Bug!	If the player uses Glowing Hourglass while in the room they used Mega Blast, the Mega Blast beam will still remain, but the animation will be removed, and a full charge for Mega Blast will be reobtained.