Binding of Isaac: Rebirth Wiki
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(except in Rebirth)

Mega Blast is an unlockable activated item added in The Binding of Isaac: Afterbirth.

Effects[ | ]

  • Upon use, Isaac fires a giant, incredibly powerful blood laser, similar to the one used by Mega Satan Head ingameMega Satan, for 15 seconds.
    • The beam deals Isaac's current damage multiplied by 5 per tick.
    • The beam has enough power to push Isaac backward while being fired and will last between rooms, and across multiple floors.
    • The beam has spectral and piercing effects.
    • The beam can be moved while firing in many angles diagonally.
    • While Mega Blast is being fired, Isaac cannot:
    • The laser extinguishes fires, detonates TNT, and destroys poop.

Notes[ | ]

  • (except in Repentance) Picking up a Lil' BatteryLil' Battery with this item will add 3 to its charge, meaning that 4 batteries are required to fully recharge the item.
  • Using a 48 Hour Energy pill with this item will fully charge it.
  • Mega Blast has an 80% decreased item pool weight, making it less likely to appear than other collectibles.
  • To unlock Mega Blast, Mega Satan must be defeated with all 13 characters.
  • (in Repentance) It is not recommended to use Mega Blast in fight with (in Repentance) Boss The Beast ingameThe Beast, because its beam forces you into obstacles on the level.
    • This can be mitigated to a degree with (in Repentance)Collectible Anima Sola iconAnima Sola, especially with a Collectible Car Battery iconCar Battery which doubles the Anima Sola's length. The Beast won't be able to spawn obstacles while chained.

Synergies[ | ]

All synergies and interactions pertaining to Collectible Brimstone iconBrimstone pertain to Mega Blast, with the following exceptions and additions:

  • (in Repentance)Collectible 4.5 Volt icon4.5 Volt: Item will gain charges for dealing damage, which is especially effective when fighting bosses with large health pool.
    • (in Repentance)Collectible Book of Virtues iconBook of Virtues: Spawns red wisps on the middle ring that utilize a miniature Brimstone as their weapon, which requires charging and releasing as usual. Lasers can hit up to 8 times for a total of 24 damage. If Mega Blast is being used, the wisps will continuously fire their laser outward rather than in the direction Mega Blast is firing
  • (in Repentance)Collectible Hemoptysis iconHemoptysis: Enemies hit by the sneeze will gain a curse that increases the damage the beam deals to 10x and +3 flat damage (instead of just 5x). Enemies who die to the beam under the curse will damage and spread the curse to nearby enemies. The sneeze can be activated while Mega Blast is firing.
  • (in Afterbirth † and Repentance)Collectible Schoolbag iconSchoolbag: Beam will continue to fire when switching to another active item. Other active items can be used while the beam is firing.
    • If Collectible Glowing Hourglass iconGlowing Hourglass is activated while under the effect of Mega Blast, as long as you hadn't yet activated Mega Blast in the previously visited room, you will keep the Megablast effect while keeping your Mega Blast fully Charged.

Interactions[ | ]

Familiars which copy Isaac's tears fire normal tears while Mega Blast is in use.

In-game Footage[ | ]

Trivia[ | ]

  • Mega Blast's collectible sprite is called 'Mega Satan's Breath' in the game files, which may be its initial name.

Gallery[ | ]

Bugs[ | ]

Bug Bug! If the player continues a run that was exited while Mega Blast was active, Isaac will retain the costume and animation of Mega Blast until the item is used again, but no beam will appear.
Bug Bug! (except in Repentance) If the player uses Collectible Glowing Hourglass iconGlowing Hourglass while in the room they used Mega Blast, the Mega Blast beam will still remain, but the animation will be removed, and a full charge for Mega Blast will be reobtained.


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