Binding of Isaac: Rebirth Wiki

Added in Repentance

Meat Cleaver is an unlockable activated item added in The Binding of Isaac: Repentance.


  • Upon use, splits enemies in the room into two smaller versions with ~40% health each.
    • Normal enemies can be split twice, while champions and bosses can be split three times. If an enemy cannot be split, they instead take 25 damage.
    • If the enemy splits as part of their mechanic, such as Squirt Squirt, Teratoma Teratoma, or The Fallen The Fallen, they will instead take the damage required to split them.
    • If the enemy has segments, such as Larry Jr. Larry Jr. or Buttlicker Buttlickers, they will have their segments cut down to half, rounding down. There are several exceptions listed in the notes section.
    • If the enemy has a cable between them, such as Mr. Maw Mr. Maw, it will immediately be cut. Mr. Maws specifically will be left with just their head.



  • Book of Virtues Book of Virtues: Spawns one red wisp on the middle ring on use. Before spawning wisps, Meat Cleaver divides all of Isaac's wisps into two wisps that deal half tear damage. Wisps will be destroyed if they try to divide a third time.
  • Filigree Feather Filigree Feather: Each split angel will drop an item.
  • Lusty Blood Lusty Blood: Each split enemy killed grants a damage boost.
  • Sigil of Baphomet Sigil of Baphomet: Split enemies will allow the shield to activate and stack up more easily.


  • Blood Puppy Blood Puppy: If Blood Puppy is angry, splits it into two copies. One copy can level up and be tamed like normal, but the other cannot level up and dies instead of being tamed.

In-game Footage[]


  • Meat Cleaver originated from the Antibirth mod.
  • This item's pickup quote is a reference to the phrase "Slice and Dice", which means to cut or divide something into smaller parts.


PC Normal mode only E1CT EDJH (Treasure Room adjacent to spawn)


Bug Bug! If used on Reap Creep, during his 3rd Phase, he cannot properly collide with the walls in order to perform his rock attack and will infinitely run against the wall.
Bug Bug! If used against Mom's foot, both will count as their own instance, and the second foot will only be able to be killed once the first one is dead.
Bug Bug! If used during Min Min's phase change, both bosses will be unable to be damaged.