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(except in Rebirth)
This article is about Lusty Blood, not to be confused with Bloody Lust.

Lusty Blood is an unlockable passive item added in The Binding of Isaac: Afterbirth.

Effects[ | ]

  • Each time an enemy is killed, Isaac gains a damage boost for the current room.
    • Each kill increases damage by 0.5, up to a maximum of 5 damage after 10 kills.

Notes[ | ]

  • Some summoned enemies like Rag Man's RaglingRag Man's Raglings do not trigger the effect when killed.
  • Mr. MawMr. Maw does not trigger the effects of Lusty Blood, even after splitting.
  • Blowing up a ShopkeeperShopkeeper will grant Isaac a damage bonus as well.

Synergies[ | ]

  • (in Repentance)Collectible Meat Cleaver iconMeat Cleaver: Both of the smaller enemies produced by Meat Cleaver add to the damage bonus, allowing rooms with few enemies to grant much more damage.
  • Samson's LockSamson's Lock: Both the item and the trinket stack, granting 1 damage per kill. With 100% proc rate on the Lock, Isaac may gain up to 10 damage after 10 kills.

Interactions[ | ]

  • (in Repentance)Ace Cards: Enemies that are turned into pickups don’t count towards the Lusty Blood counter.
  • Collectible E. Coli iconE. Coli/Collectible Flush! iconFlush!: Enemies that are turned into poop don't count towards the Lusty Blood counter.
  • (in Repentance)Freeze Effects: Enemies that are frozen don't count towards the Lusty Blood counter.
    • Because of this interaction, when Isaac has (in Repentance)Collectible Uranus iconUranus, only enemies killed by icicles from statues, bombs, familiars and other sources will increment Lusty Blood's counter, thus rendering Lusty Blood quite difficult to use.

In-game Footage[ | ]

Trivia[ | ]

  • Lusty Blood has the same effect as Collectible Bloody Lust iconBloody Lust from the original The Binding of Isaac.


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