Binding of Isaac: Rebirth Wiki
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(in Afterbirth † and Repentance)

Locust of Pestilence is an unlockable trinket added in The Binding of Isaac: Afterbirth †.

Effects[ | ]

  • Upon entering a room with enemies, spawns a Green Locust that deals double Isaac's damage and poisons enemies, which deals double Isaac's damage over time.

Notes[ | ]

  • The Locust will also spawn each time a wave starts in Boss RushBoss Rush.
  • The Locust will not spawn each time a wave starts in Greed mode onlyGreed Mode.

In-game Footage[ | ]


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