Binding of Isaac: Rebirth Wiki
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Locust of Pestilence

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(in Afterbirth † and Repentance)

Locust of Pestilence is an unlockable trinket added in The Binding of Isaac: Afterbirth †.

Effects[]

  • Upon entering a room with enemies, spawns a Green Locust that deals double Isaac's damage and poisons enemies, which deals double Isaac's damage over time.

Notes[]

  • The Locust will also spawn each time a wave starts in Boss RushBoss Rush.
  • The Locust will not spawn each time a wave starts in Greed mode onlyGreed Mode.

In-game Footage[]


Locusts
Items
Trinkets
Runes
Apollyon Unlocks Apollyon Unlocks Apollyon Unlocks
(in Afterbirth † and Repentance)
VoidBlack RuneLocust of WrathLocust of PestilenceLocust of FamineLocust of DeathLocust of ConquestHushyBrown NuggetMort BabySmelterApollyon Baby 		(in Repentance)
Lil PortalWorm FriendThe Empty
Satan Unlocks Satan Unlocks Satan Unlocks

JudasMom's KnifeThe RazorGuardian AngelA Bag of BombsForget Me NowBlood RightsJudas' TongueThe NegativeBroken AnkhBook of SecretsDaemon's TailThe Mind 		(except in Rebirth)
Serpent's KissKeeper holds Store Key 		(in Afterbirth † and Repentance)
Locust of PestilencePointy Rib 		(in Repentance)
Urn of SoulsRed StewBaptism by FireMom's LockHoly CrownGilded KeyYour SoulDingle BerryStrange KeyTemporary TattooWicked CrownTorn PocketNuh Uh!Kid's DrawingThe TwinsKeeper's BargainCricket LegPolished BoneExpansion PackRC Remote
The Binding of Isaac: Rebirth
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