Binding of Isaac: Rebirth Wiki

Little Baggy is a passive item.


  • Allows Isaac to carry two pills. Tapping the Drop button will cause a cycle through the two pills.
  • Spawns a random pill.
  • Removed in Repentance Changes all card and rune drops into pills.
  • Added in Repentance Only changes card drops into pills.
    • Any Tarot card or rune held when picking this item up will change into a pill.
    • Removed in RepentanceDice Shard Dice Shard counts as a card and will be converted.
    • Added in Repentance If playing as Jacob and Esau Jacob and Esau, if one character picks up Little Baggy while the other character holds a card, that card will remain until used or dropped.
  • Added in Repentance Blowing up the skull marked with a small "X" in Depths Depths will drop Telepills instead of 0 - The Fool 0 - The Fool.
    • But already generated 0 - The Fool 0 - The Fool cards will NOT be transformed into Telepills and could become any pill, thereby making the Ascent impossible!
  • Added in Repentance Tainted characters or anyone who already has an active item in the pill slot will be allowed a third slot for pills.


  • Crystal Ball Crystal Ball: Generates pills instead of cards upon use.
  • Deck of Cards Deck of Cards: Generates pills instead of cards upon use, similar toMom's Bottle of Pills Mom's Bottle of Pills.
  • Added in RepentanceFalse PHD False PHD: Since all cards turn to pills, there is potential for a lot of damage ups.
  • PHD PHD/Virgo Virgo: Most negative pills will be converted to their positive counterparts.
    • Added in Repentance Lucky Foot Lucky Foot: Most negative pills will be converted to their positive counterparts.
  • Removed in Repentance Starter Deck Starter Deck: Overrides Little Baggy. Pills may still be for sale in shops, but dropping them turns them into cards.
    • Added in Repentance Having both items allows both cards and pills to appear again.
    • Picking up Starter Deck while already holding Little Baggy will turn any held pills into cards for one time.

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