Little Baggy is a passive item.
Effects[]
- Allows Isaac to carry two pills. Tapping the Drop button will cause a cycle through the two pills.
- Spawns a random pill.
- Changes all card and rune drops into pills.
- Any Tarot card or rune held when picking this item up will change into a pill.
Dice Shard counts as a card and will be converted.- Cracked Key counts as a card and will be converted.
- If playing as Jacob and Esau, if one character picks up Little Baggy while the other character holds a card, that card will remain until used or dropped.
- Blowing up the skull marked with a small "X" in Depths will drop Telepills instead of 0 - The Fool.
- Tainted characters or anyone who already has an active item in the pill slot will be allowed a third slot for pills.
Interactions[]
- Crystal Ball: Generates pills instead of cards upon use.
- Deck of Cards: Generates pills instead of cards upon use, similar to Mom's Bottle of Pills.
- False PHD: Since all cards turn to pills, there is potential for a lot of damage ups.
- PHD/ Virgo: Most negative pills will be converted to their positive counterparts.
- Lucky Foot: Most negative pills will be converted to their positive counterparts.
- Starter Deck: Overrides Little Baggy. Pills may still be for sale in shops, but dropping them turns them into cards.
- Having both items allows both cards and pills to appear again.
- Picking up Starter Deck while already holding Little Baggy will turn any held pills into cards for one time.
In-game Footage[]
 Inventory Expansion
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| Active items |
| Coins |
| Cards/Pills |
| Trinkets |
 The Binding of Isaac: Rebirth
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 Achievements
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 Attributes
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 Bosses
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 Cards and Runes
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 Challenges
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 Chapters
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 Characters
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 Co-op
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 Items
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 Item pools
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 Monsters
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 Objects
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 Pickups
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 Pills
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 Rooms
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 Seeds
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 Transformations
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 Trinkets
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