The Incubus can be found as a separate item, and picking it up will grant Lilith another Incubus familiar.
The Incubus does 100% of Lilith's damage stat, while doing only 75% with other characters, except Tainted Lilith.
Lilith's Incubus familiar copies whatever tears she would fire if she weren't blindfolded. Combined with the Box of Friends, the basic strategy for her is to simply multiply her damage. Powerful tear modifiers such as Polyphemus will become even more deadly if Lilith can create several Incubi.
When shooting, keep in mind that Incubus lingers behind you.
Dr. Fetus is not recommended, since your movement may block the bomb, which causes self-damage easily.
Incubus has reduced tear size, which makes some items harder to use (The Ludovico Technique, for example).
Due to her starter item Box of Friends, she strongly benefits from other familiars and familiar enhancers like BFFS!.
Battery items are very useful for Lilith so she can continue to use the Box of Friends.
9 Volt will reduce it to a 3-room ( 2-room) charge, allowing it to be used more often.
The Battery can prove to be very useful as Lilith, allowing you to create three copies of the incubus and any other familiar in the same room.
Car Battery will double the effect of the item, meaning she'll create 2 copies of each familiar per use.
Charged Baby creates batteries or recharges your item by one bar occasionally, and is also duplicated by the Box of Friends. The more the player creates, the more often they will obtain batteries and charges from the increasing number of charged babies.
Activated Items recharge per-wave in Greed Mode and Boss Rush, allowing Lilith to use the Box of Friends very often. Familiars like The Relic and Little C.H.A.D. could give the player an endless amount of health if used correctly.
Due to this, during Greed mode, it is most effective to stay within the Arena for every wave in order to maximize the amount of familiars you have upon reaching the boss waves.
4.5 Volt replaces the per-wave charging. With only this, compared to no battery items, starting and ending fully charged, it's typically possible to use Box of Friends once or twice more in a full set of Greed Mode waves.
While other activatable items may have some form of use, it is not advised to permanently trade out the Box of Friends. Without it, Lilith loses what is essentially her greatest strength, as Incubus shooting in her place is only a positive with its usage.
If Lilith dies with an extra life item that changes her to a different character (Ankh, Lazarus' Rags, Judas' Shadow), she will lose both her blindfold and the intrinsic Incubus familiar.
Despite this, Lilith's Incubus still counts as an actual item.
Heart Containers, healing items, and Heart-generating items (Charm of the Vampire, Humbleing Bundle, etc.) indirectly benefit Lilith since her Cambion Conception gives her additional familiars after taking multiple hits. Use a fireplace or Heart Donation Machine to damage yourself multiple times to speed up the familiar-generating process (preferably after killing the boss to not hurt your Devil/Angel Room spawn chances).
Epic Fetus: Lilith can use the Epic Fetus while her Incubi still fire what her tears would be without Epic Fetus.
Forgotten Lullaby is effectively a tears up for the Incubus familiar, and can also boost any other familiars Lilith might get.
Hypercoagulation: By intentionally taking damage with something like a fire and grabbing the half-red hearts, Lilith can easily generate powerful familiars for free.
Cursed Eye ends up being a powerful item due to this, as it causes Incubus to fire three tears per shot with no charging, while Lilith doesn't have to worry about getting teleported by accident as she cannot charge up.
Maw Of The Void: Obtaining The Ludovico Technique is necessary to utilize Maw Of The Void to its fullest, as it will allow Lilith to create the damaging black ring around her.
Mom's Knife: Gives Incubus a smaller version of the item with the same base range as Isaac; However, Lilith will not get this to use due to her blindfold.
This knife can be used with Incubus to give it contact damage with no danger to Lilith.
My Reflection: Unless you have a beam weapon (such as Brimstone/Technology), picking up My Reflection is a bad idea, as it will greatly shorten Incubus' range without the possibility to increase it.
You can now increase Incubus' range on top of being a good dmg up.
Spirit Sword: The sword is held by the Incubus and acts the same way as with other characters.
Brimstone + The Ludovico Technique: Synergizes together to become a large controllable ring per incubus. Multiple rings may completely overlap.
Ineffective Items[]
These items will not affect Lilith due to her blindfolded condition and certain limitations of Incubus.
Note: As mentioned above, certain items will apply their normal effects if Lilith obtains The Ludovico Technique.
Analog Stick (Tears up is applied, but Incubus cannot fire in 360 degrees) Edit: Incubus at least with Lilith may actually shoot diagonally, so item works with Lilith
Lilith is the Hebrew name for a figure in Jewish mythology, thought to be derived from Mesopotamian mythology.
Although Lilith is only mentioned in passing in the Biblical Book of Isaiah, later Jewish mythology expanded on her. In some stories, Lilith is the original woman God created before Eve. She refused to become subservient to Adam and left Eden; in others, she is depicted as the bane of humanity when Adam refused her, driving her to curse all of his descendants and targets children under her grudge.
Cambion Conception is always listed as one of Lilith's starting items, even if it has not been unlocked.
Lilith, as well as The Lost and Bethany, are the only non-tainted characters whose unlock conditions require a specific character.
Lilith's starting health is listed as "?" on the character selection screen.
Lilith's starting health is listed as "I" on the character selection screen, despite starting with one red heart and two black hearts.
Lilith's locked character icon is a locked box with her Incubus on it.
The recharge time of Box of Friends has been changed multiple times in order to balance Lilith. On her initial release, it recharged in just 2 rooms. Then an update increased the recharge time to 4 rooms. Finally, in Repentance, its recharge time was decreased to 3 rooms.
Black Hearts. Lilith's starting items are the 
Box of Friends, 
Incubus, and 
Cambion Conception. Lilith is permanently blindfolded, meaning she has no ability to fire tears; she instead deals damage with the 
Azazel.
The Incubus does 100% of Lilith's damage stat, while doing only 75% with other characters, except 
The Ludovico Technique.
Azazel Unlocks 
Lilith Unlocks 
Ultra Greed Unlocks 
Characters 
The Binding of Isaac: Rebirth
