- Upon taking damage, Isaac gains a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with.
- A maximum of three body parts can be active at once.
- The body parts will be destroyed after dealing 30 ticks of damage and/or blocking 3 shots.
- The body parts persist between floors.
- Body parts orbit on the same layer as Blue Flies and Locusts do.
- Box of Friends: Will not multiply orbitals.
- The description "You're tearing me apart!" is a reference to the movie The Room (which Edmund has said he is a big fan of), in which Tommy Wiseau famously exclaims "You're tearing me apart, Lisa!".
- Leprosy was added in Booster Pack #2, after the initial release of the DLC.
- Leprosy was inspired by a Steam Workshop item by Bobby Lashley Fangirl #1.
- The item used to be misspelled "Leprocy" but was corrected in a later patch.
- Its appearance is changed slightly for The Forgotten due to his lack of skin, making him look like Melting from the game Nuclear Throne.
- The item is a reference to leprosy, a bacterial disease that damages nerves and can cause extremities to rot in extreme cases.
|The Binding of Isaac: Rebirth|
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|