Binding of Isaac: Rebirth Wiki

Added in Afterbirth †

Large Zit is a passive item added in The Binding of Isaac: Afterbirth †.


  • While firing, Isaac has a chance to fire an additional creep shot that deals double damage, slows enemies, and leaves a short trail of white creep that also slows enemies.
    • The chance is not affected by luck.
    • The creep shots don't take on any tear effects.
    • Removed in RepentanceThe creep shots are affected by range and shot speed.
      • Added in RepentanceThe creep shots are not affected by range but affected by shot speed, which determines their effective range.
    • Their tear sizes are not affected by their damage. They always retain their small size.
  • A creep shot will also be fired in a random direction when taking damage.



In-game Footage[]


  • Large Zit was originally an unofficial item which was supposed to showcase the modding capabilities of Afterbirth+ in the PAX 2016 livestream. However, all items included in the demo were later added to the final game.


PC Normal and hard modes only JPV6 AHEQ

Switch Greedier mode only 1JKG C94H (First Golden Treasure Room)