Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Repentance

Knockout Drops is a passive item added in The Binding of Isaac: Repentance.


  • Adds a 10% chance to shoot red fist-shaped tears that deal extreme knockback and cause confusion for 2 seconds.
    • Enemies that are knocked back will take/deal 10 + 2 * (floor - 1) damage to and knock back any enemies they are knocked into, as well as if they run into a wall/obstacle.
  • The chance to fire fist tears is affected by luck. At base luck (0), the chance is 10%, maxing out at 100% at 9 luck.


  • Bosses are also affected by all of Knockout Drops' effects.
  • Fist tears play a unique punch sound effect when they hit enemies.


  • 15►Aquarius Aquarius: The trail of tears has a chance to knockback enemies.
  • 15►Brimstone Brimstone: Gives the lasers high knockback.
  • 15►Jacob's Ladder Jacob's Ladder: Enemies that are shocked by a knockback tear will also be knocked back.

In-game footage[]



  • Taking this item as Keeper will give him the expression of Bum-Bo the Brave, and by extension, Bumbino.


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