Key Piece 2 is an unlockable passive item.
Effect[ | ]
- Combined with
Key Piece 1, unlocks the golden gate in the starting room of Chest and Dark Room to fight Mega Satan. - Increases the chance of finding an Angel Room.
- Grants a 2.5% chance of converting Red Heart pickups into Eternal Hearts.
- This effect stacks with Key Piece 1.
- This effect stacks with
Notes[ | ]
- This item is a guaranteed drop from Gabriel if not already in possession.
- This item, along with Key Piece 1, can be rerolled into any item from the Angel Room pool.
- This item also counts as a familiar, meaning it takes up a familiar slot.
- Unlocking the Golden Gate with the combined key pieces and then restarting the floor with Forget Me Now or an I AM ERROR room will waste the key, which will not respawn.
- Will not be rerolled by D4, D100, or Dice Room effects.
- Will not be doubled by Box of Friends
- Familiars that follow behind Isaac have a certain priority in how close their position is to him over other familiars, with Key Piece 2 having the lowest priority at 6th and thus being farther from Isaac than familiars of different priorities.
In-game Footage[ | ]
Unlockable achievements[ | ]
- The Family Man - Pick up both Key Pieces from the Angels in one run.
Trivia[ | ]
- This item is used in I RULE! (challenge #26) and Ultra Hard (challenge #34).
 Keys
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| Trinkets |
| Cards and Runes |
 The Binding of Isaac: Rebirth
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