Keeper's Box

Item Icon
Pickup Quote	"Portable shop"
Entity ID	5.100.719
Recharge Time	4 rooms
Item Pool	Secret Room Shop Wooden Chest Secret Room Treasure Room
Quality	2
Item Tags
Collection Grid	(page 6, column 4, row 6)
Unlock Method	Defeat The Beast as Keeper

Keeper's Box is an unlockable activated item added in The Binding of Isaac: Repentance.

Effects

• Spawns a random pickup or item, which must be bought for its normal Shop price.
  • Items generated by the box will always be shop items.
    • If used while playing as Tainted Isaac, the alternate item will be from the pool of the room it's used in.
  • The pickup/item will be surrounded by spikes/cost hearts if the box is used in a Devil Room, a Black Market, or if Isaac has A Pound of Flesh.

Notes

• The items spawned by the box are affected by Steam Sale and can be made free by Coupon.
• All items and pickups spawned by the Keeper's Box can be rerolled by a Dice Room number 3 as if they were consumables.
• Keeper's Box can spawn hearts when used as Keeper or Tainted Keeper, unlike normal shops. They cannot be purchased by these characters, however.

Synergies

• Stat upgrades from the items spawned can be gained using Keeper's Sack even when shops become unavailable (Floors after the Mom fight excluding ???)
• Book of Virtues: Spawns glowing coin wisps on the middle ring. Enemies killed by the wisps' tears have a 20% chance to drop a Penny.

Interactions

• Adoption Papers: Does not affect Keeper's Box' items, meaning both familiars and shop items can be purchased in tandem over the course of a run.
• Chaos / Sacred Orb / TMTRAINER: Affects items spawned by the box.
• A Pound of Flesh: Items spawned by Keeper's Box are purchased with red heart containers and pickups are purchased with health, just like a regular shop item.
• Store Credit: Cannot be used on consumables or items spawned by Keeper's Box.

Trivia

• Keeper's Box has a similar shape to Pandora's Box, along with a keyhole in the same position.
• This item is similar to Portable Slot, and the pickup quote (Portable shop) may be a reference to it.

The Binding of Isaac: Rebirth
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