Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Repentance

Keeper's Box is an activated item added in The Binding of Isaac: Repentance.


  • Spawns a random pickup or item, which must be bought for its normal shop price.


  • The items spawned by the box are affected by Steam Sale Steam Sale and can be made free by Coupon Coupon.
  • All items and pickups spawned by the Keeper's Box can be rerolled by a Dice Room number 3 as if they were consumables.


  • Stat upgrades from the items spawned can be gained using Keeper's Sack Keeper's Sack even when shops become unavailable (Floors after the Mom fight excluding ??? (Floor))


  • Adoption Papers Adoption Papers: Does not affect Keeper's Box' items, meaning both familiars and shop items can be purchased in tandem over the course of a run.

In-game footage[]


  • Keeper's Box has a similar shape to Pandora's Box, along with a keyhole in the same position.
  • This item is similar to Portable Slot, and the pickup quote (Portable shop) may be a reference to it.