Binding of Isaac: Rebirth Wiki
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(in Repentance)

Keeper's Box is an unlockable activated item added in The Binding of Isaac: Repentance.

Effects[ | ]

  • Spawns a random pickup or item, which must be bought for its normal ShopShop price.
    • Items generated by the box will always be shop items.
      • If used while playing as Character Tainted Isaac iconTainted Isaac, the alternate item will be from the pool of the room it's used in.
    • It has an equal ~11.1% chance to spawn a card, pill, bomb, key, battery, item, soul heart, red heart, or a sack.
    • The pickup/item will be surrounded by spikes/cost hearts if the box is used in a Devil RoomDevil Room, a Black MarketBlack Market, if Isaac has Collectible A Pound of Flesh iconA Pound of Flesh or is in a boss room after using Collectible Satanic Bible iconSatanic Bible.

Notes[ | ]

  • Keeper's Box can spawn hearts when used as Character Keeper iconKeeper or Character Tainted Keeper iconTainted Keeper, unlike normal shops. They cannot be purchased by these characters, however.

Synergies[ | ]

  • Collectible Book of Virtues iconBook of Virtues: Spawns glowing coin wisps on the middle ring. Enemies killed by the wisps' tears have a 20% chance to drop a random coin.
  • Collectible Coupon iconCoupon / Collectible Mr. ME! iconMr. ME! / Collectible Crooked Penny iconCrooked Penny + Collectible Schoolbag iconSchoolbag: Spawned pickups/items can be made free.
  • Collectible D20 iconD20 + Collectible Schoolbag iconSchoolbag: Rerolled pickups have a chance to reroll into an item from the current room's item pool.
  • Collectible Keeper's Sack iconKeeper's Sack: Stat upgrades from the spawned pickups/items can be gained even when shops become unavailable (Floors after the Boss Mom ingameMom fight excluding ??????).
  • Collectible Restock iconRestock: Buying spawned pickups in the ShopShop will always respawn them as items and their prices will never increase. This does not work outside of the shop. It also works in Greed and Greedier modes, although it will respawn them as (random) pickups.
  • Collectible Steam Sale iconSteam Sale: Spawned pickups/items will be on sale.

Interactions[ | ]

  • Adoption PapersAdoption Papers: Does not affect Keeper's Box' items, meaning both familiars and shop items can be purchased in tandem over the course of a run.
  • Collectible Chaos iconChaos / Collectible Sacred Orb iconSacred Orb / Collectible TMTRAINER iconTMTRAINER: Affects items spawned by the box.
  • Store CreditStore Credit: Cannot be used on consumables or items spawned by Keeper's Box outside of the Shop.

In-game footage[ | ]

Trivia[ | ]

  • Keeper's Box has a similar shape to Collectible Pandora's Box iconPandora's Box, along with a keyhole in the same position.
  • This item is similar to Collectible Portable Slot iconPortable Slot, and the pickup quote (Portable shop) may be a reference to it.


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