Items
Items are an integral part of the game-play of The Binding of Isaac: Rebirth. They modify Isaac's attributes, grant or modify tear effects, and much more.
Items are classified into several distinct types and groups. Some items are passive, which add an effect permanently to Isaac, while others only activate when used. The original The Binding of Isaac had 196 items. Rebirth has a total of 341 items. Afterbirth added 95 new items, for a total of 436 items.
Afterbirth † added 111 new items, for a total of 547 items. In Afterbirth † and prior, 13 items are considered special and will be less likely to appear if the player has already come across other special items. The Repentance expansion removed the Special Item mechanic.
For a list of which items can potentially appear in a given special room, see item pool, Item Tags, and item pool weight.
For the grids of items that appear in the stats menu, see Collection Page.
Not to be confused with cards and runes, pills, and trinkets.
Activated Collectibles
Unless the player has Schoolbag, only one activated item can be held at a time, with the old collectible being placed on a pedestal if a new activated item is picked up. Most activated items need to recharge before use, with the recharge bar filling either by clearing rooms or recharging over time. Other activated items do not have a charge bar, and, with a few exceptions (such as
How to Jump), will instead either disappear after a single use or require resources such as coins or health. Some activated items will also grant passive effects as long as they are equipped.
Name | ID | Icon | Quote | Description | ![]() |
---|---|---|---|---|---|
A Pony | 5.100.130 | ![]() |
Flight + Dash Attack | Passively gives flight and increases speed to 1.5. Upon use, Isaac charges in the direction the pony is facing, giving invincibility during the charge and dealing 40 damage. | 2 |
Anarchist Cookbook | 5.100.65 | ![]() |
Summon bombs | Spawns six Troll Bombs around the room. | 1 |
Best Friend | 5.100.136 | ![]() |
Friends 'till the end | Spawns a decoy Isaac that eventually explodes with an increased blast radius. | 1 |
Blank Card | 5.100.286 | ![]() |
Card mimic | ![]() ![]() |
2 |
Blood Rights | 5.100.186 | ![]() |
Mass enemy damage at a cost | Upon use, takes a full heart of health and deals 40 damage to all enemies in the room. | 0 |
Bob's Rotten Head | 5.100.42 | ![]() |
Reusable ranged bomb | Upon use, Isaac holds a poison bomb which can be thrown in the cardinal directions and explodes on impact. | 1 |
Book of Revelations | 5.100.78 | ![]() |
Reusable soul protection | Gives one Soul Heart, increases the chance for a Devil or Angel Room, and changes the boss of the current floor to a Harbinger if possible. | 3 |
Book of Secrets | 5.100.287 | ![]() |
Tome of knowledge | Gives the effect of ![]() ![]() ![]() |
0 |
Book of Shadows | 5.100.58 | ![]() |
Temporary Invincibility | Creates a protective shield, nullifying all types of damage for 10 seconds. | 2 |
Box of Spiders | 5.100.288 | ![]() |
It's a box of spiders | ![]()
|
1 |
Breath of Life | 5.100.326 | ![]() |
Invincibility at a cost | Grants a brief moment of invincibility when the charge bar hits zero. If the spacebar is held for an additional second after hitting zero, Isaac will take damage. | 0 |
Butter Bean | 5.100.294 | ![]() |
Reusable knock-back | ![]()
|
0 |
Converter | 5.100.296 | ![]() |
Convert your soul | ![]()
|
1 |
Crack the Sky | 5.100.160 | ![]() |
Holy white death | Summons 5 beams of light in random locations on the ground, dealing large amounts of damage to any enemies that touch them. | 2 |
Crystal Ball | 5.100.158 | ![]() |
I see my future | Upon use, reveals the map (except the Super Secret Room) and drops a Soul Heart or random card/rune. | 2 |
D10 | 5.100.285 | ![]() |
Rerolls enemies | Rerolls the monsters in the room. Only rerolls monsters that are still alive (does not spawn new enemies). | 0 |
D100 | 5.100.283 | ![]() |
REEROLLLLL! | ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
3 |
D20 | 5.100.166 | ![]() |
Reroll the basics | Rerolls all pickups in the current room. | 2 |
D4 | 5.100.284 | ![]() |
Reroll into something else | Rerolls all of Isaac's passive items. | 3 |
Dad's Key | 5.100.175 | ![]() |
Opens all doors... | Opens all doors in the current room when activated, including doors which require a key to open and entrances to Secret Rooms. Opens the big doors in the first room of both ![]() ![]() |
1 |
Dead Sea Scrolls | 5.100.124 | ![]() |
It's a mystery | Triggers the effect of a random activated item from a list of possible options (not every activated item is included). | 1 |
Deck of Cards | 5.100.85 | ![]() |
Reusable card generator | Gives Isaac a random card. | 1 |
Doctor's Remote | 5.100.47 | ![]() |
Reusable Air Strike | Creates a crosshair on the ground that can be aimed with tear controls. A missile strikes the spot after 2 seconds, creating a heavy damage explosion. | 1 |
Flush! | 5.100.291 | ![]() |
... | Turns all non-boss monsters in the room into poop. Instantly kills poop-themed bosses. | 1 |
Forget Me Now | 5.100.127 | ![]() |
I don't remember | On use, re-generates the current floor with a new layout. Isaac loses Forget Me Now, but keeps other items and consumables picked up on the original floor. | 3 |
Guppy's Head | 5.100.145 | ![]() |
Reusable fly hive | Spawns 2-4 friendly Blue Flies that damage enemies. | 3 |
Guppy's Paw | 5.100.133 | ![]() |
Soul converter | Upon use, converts one Heart Container into three Soul Hearts. | 3 |
Head of Krampus | 5.100.293 | ![]() |
Krampus Rage | Fires a powerful ![]()
|
2 |
How to Jump | 5.100.282 | ![]() |
It's about time you learned how | Upon use, Isaac jumps in the direction he is currently moving, allowing travel over obstacles and enemies. | 1 |
Isaac's Tears | 5.100.323 | ![]() |
Collected tears | Fires 8 tears around Isaac, which retain the damage, range, shot speed, and special tear effects. Each tear shot by Isaac increases item charge by one. | 0 |
IV Bag | 5.100.135 | ![]() |
Portable blood bank | Upon use, Isaac loses half a heart of health (one in ![]() |
1 |
Kamikaze! | 5.100.40 | ![]() |
Become the bomb! | Upon use, creates an explosion in the same place as Isaac, damaging him for half a heart and dealing 40 damage to all enemies caught in the blast. | 0 |
Lemon Mishap | 5.100.56 | ![]() |
Oops... | Creates a tiny pool of yellow creep, damaging enemies that cross it. | 1 |
Magic Fingers | 5.100.295 | ![]() |
Pay to play | Uses 1 coin to deal twice Isaac's damage to all enemies in the room. | 1 |
Mom's Bottle of Pills | 5.100.102 | ![]() |
Reusable pill generator | Gives Isaac a random pill. | 1 |
Mom's Bra | 5.100.39 | ![]() |
Mass Fear | Petrifies all enemies in the current room for around 4 seconds. | 1 |
Mom's Pad | 5.100.41 | ![]() |
Gross... | Inflicts fear to all enemies in the room for 5 seconds. | 0 |
Monster Manual | 5.100.123 | ![]() |
Temporary buddy generator | ![]()
|
0 |
Monstro's Tooth | 5.100.86 | ![]() |
Summon Monstro | A friendly Monstro jumps on a random enemy, dealing 120 area damage. Lands on Isaac if used in a room without enemies. | 1 |
Mr. Boom | 5.100.37 | ![]() |
Reusable bomb buddy | Places a Mr. Mega bomb that deals 110 damage. | 1 |
My Little Unicorn | 5.100.77 | ![]() |
Temporary badass | Gives invulnerability and +0.28 speed for six seconds, removing the ability to shoot tears and replacing it with the ability to deal 40 contact damage to enemies. | 1 |
Notched Axe | 5.100.147 | ![]() |
Rocks don't stand a chance | ![]()
|
0 |
Pandora's Box | 5.100.297 | ![]() |
?? | Upon use, spawns specific pickups or items depending on the floor it is used on. Disappears after use. | 2 |
Portable Slot | 5.100.177 | ![]() |
Gamble 24/7 | Upon use, consumes 1 coin and has a chance to drop a random pickup, like a slot machine. | 0 |
Prayer Card | 5.100.146 | ![]() |
Reusable eternity | Gives an Eternal Heart per use. | 3 |
Razor Blade | 5.100.126 | ![]() |
Feel my pain | On use, takes one heart of health and grants +1.2 damage for the current room. | 0 |
Red Candle | 5.100.289 | ![]() |
Flame on | Throws a flame that that can pass over gaps (but not through obstacles). The flame damages everything in its path, diminishing in size as it hits enemies or blocks shots. | 2 |
Remote Detonator | 5.100.137 | ![]() |
Remote bomb detonation | Bombs placed by Isaac only explode when Remote Detonator is used. Gives 5 bombs. | 1 |
Satanic Bible | 5.100.292 | ![]() |
Reusable Evil... But at what cost? | Gives one Black Heart. ![]() |
4 |
Scissors | 5.100.325 | ![]() |
Lose your head | ![]()
|
0 |
Shoop Da Whoop! | 5.100.49 | ![]() |
BLLLARRRRGGG! | Fires a laser from Isaac's mouth. | 1 |
Spider Butt | 5.100.171 | ![]() |
Mass enemy slowdown + damage | Deals 10 damage to all enemies in the room and slows them for 4 seconds. | 1 |
Tammy's Head | 5.100.38 | ![]() |
Reusable tear burst | Shoots 10 tears in a circle around Isaac, which retain the damage, shot speed, and special effects (such as poison) of Isaac's tears. | 3 |
Telepathy for Dummies | 5.100.192 | ![]() |
Temporary psychic shot | Gives homing tears for the current room. | 0 |
Teleport | 5.100.44 | ![]() |
Teleport! | Teleports Isaac to a random room on the current floor. | 0 |
The Bean | 5.100.111 | ![]() |
Toot on command | Isaac farts, poisoning any enemy in close range. | 0 |
The Bible | 5.100.33 | ![]() |
Temporary Flight | On use, Isaac gains flight for the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but kills Isaac when used on Satan. | 1 |
The Book of Belial | 5.100.34 | ![]() |
Temporary DMG up | +2 damage for the current room. ![]() ![]() |
3 |
The Book of Sin | 5.100.97 | ![]() |
Reusable Item Generator | Spawns a random pickup, pill, card, or trinket. | 2 |
The Boomerang | 5.100.338 | ![]() |
It will never leave you | Throws a boomerang which retrieves pickups, as well as damages and petrifies enemies hit for 2 seconds. | 1 |
The Candle | 5.100.164 | ![]() |
Reusable flame | Throws out a temporary flame that can pass over gaps (but not through rocks). The flame damages anything in its path. | 2 |
The D6 | 5.100.105 | ![]() |
Reroll Your Destiny | Re-rolls all items in the current room into other items, depending on the current room's Item Pool. | 4 |
The Gamekid | 5.100.93 | ![]() |
Temporary Man-Pac | Turns Isaac into a into a Pac-Man-like creature for 6 seconds, granting invulnerability, inflicting fear on all enemies, and replenishing a Half Red Heart for every two enemies killed. | 2 |
The Hourglass | 5.100.66 | ![]() |
Temporary enemy slowdown | All enemies in the room are slowed for 8 seconds. | 1 |
The Jar | 5.100.290 | ![]() |
Save your life | When at full health, up to 4 extra Red Hearts can be stored in The Jar. | 0 |
The Nail | 5.100.83 | ![]() |
Temporary demon form | Gives ![]() ![]() |
3 |
The Necronomicon | 5.100.35 | ![]() |
Mass room damage | Deals 40 damage to every enemy in the room. | 1 |
The Pinking Shears | 5.100.107 | ![]() |
Cut and Run | Gives flight for the current room, while turning Isaac's body into a fast, high damage familiar. | 3 |
The Poop | 5.100.36 | ![]() |
Plop! | Spawns a pile of poop where the Isaac is standing and knocks back nearby enemies. May yield pickups like regular poop. | 0 |
Undefined | 5.100.324 | ![]() |
Undefined | Teleports Isaac to the Secret Room, Super Secret Room, Treasure Room, or I AM ERROR. | 2 |
Unicorn Stump | 5.100.298 | ![]() |
You feel stumped | Gives invulnerability and increased speed for five seconds, but removes the ability to shoot tears. | 1 |
We Need to Go Deeper! | 5.100.84 | ![]() |
Reusable level skip | Creates a trapdoor to go to the next floor. If used in ![]() ![]() |
0 |
White Pony | 5.100.181 | ![]() |
Flight + holy death | Passively gives flight and increases speed to 1.5. Upon use, Isaac charges in the direction the pony is facing, giving invulnerability during the charge and dealing 40 damage while also casting the effect of Crack the Sky. | 2 |
Yum Heart | 5.100.45 | ![]() |
Reusable Regeneration | Restores one Red Heart of Isaac's health. | 1 |
![]() |
5.100.357 | ![]() |
Double your friends | Duplicates all of Isaac's familiars for the current room. If Isaac has no familiars, spawns a ![]() |
1 |
![]() |
5.100.386 | ![]() |
Rerolls rocks | Re-rolls all rocks in the current room into other random objects, such as bomb rocks, metal blocks, TNT, or poops. | 0 |
![]() |
5.100.437 | ![]() |
Reroll rewards! | Restarts the current room and brings back all enemies, allowing more rewards to be acquired by completing the room. | 1 |
![]() |
5.100.406 | ![]() |
Reroll stats | Re-rolls Isaac's damage, tears, range, and speed. | 2 |
![]() |
5.100.347 | ![]() |
Double item vision | Duplicates all pickups and item pedestals in the room. | 3 |
![]() |
5.100.382 | ![]() |
Gotta fetch 'em all! | Throwing the ball at a monster instantly kills and captures it. The captured enemy can later be released and will be friendly, fighting for Isaac and persisting between rooms. | 1 |
![]() |
5.100.352 | ![]() |
Be gentle... | ![]() ![]() ![]() ![]() |
1 |
![]() |
5.100.422 | ![]() |
Turn back time | When used, this item will rewind time, put Isaac back in the previous room, and undo anything that happened in the current room. Any health, pickups, or items gained or lost will be reset back to the previous state. | 1 |
![]() |
5.100.434 | ![]() |
Gotta catch 'em all? | Killing an enemy adds a fly to the jar, up to a maximum of 20. On use, releases Blue Flies equal to the number of flies in the jar. | 2 |
![]() |
5.100.421 | ![]() |
Love toots! | Isaac farts, charming all nearby enemies. | 0 |
![]() |
5.100.351 | ![]() |
Giga fart! | Petrifies all enemies in the current room for a couple of seconds, poisons any enemies near Isaac, and sends a rock wave across the room in the direction Isaac is facing. | 1 |
![]() |
5.100.441 | ![]() |
Laser breath | Upon use, Isaac fires a laser similar to the one used by Mega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active. | 4 |
![]() |
5.100.427 | ![]() |
Booom! | Places an explosive TNT barrel that can be pushed and used to destroy rocks or damage enemies when used. If used a second time in the same room while the previous TNT barrel is still intact, it will remotely explode the TNT. | 1 |
![]() |
5.100.439 | ![]() |
What's inside? | When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets. | 3 |
![]() |
5.100.348 | ![]() |
Pill mimic | When used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes. | 2 |
![]() |
5.100.383 | ![]() |
Remote tear detonation! | When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head. | 1 |
![]() |
5.100.419 | ![]() |
I-Teleport! | Teleports Isaac to a random room that has not been explored yet when used. If all rooms are explored, including secret rooms, it will teleport Isaac to the Devil or Angel room. If all rooms are explored, including the Devil or Angel room, it will teleport Isaac to the I AM ERROR room. If used in a room with enemies, it will teleport Isaac out and back into the same room. | 2 |
![]() |
5.100.396 | ![]() |
Short cutter | Can be used to place an orange portal and a blue portal. Upon entering a portal, Isaac is teleported to the other portal. | 1 |
![]() |
5.100.349 | ![]() |
Flip a coin | When used, has a 50% chance to drop one random type of coin (Penny, Nickel, or Dime). | 1 |
![]() |
5.100.512 | ![]() |
Nothing can escape | Throws a black hole on the ground which sucks in and damages enemies. | 1 |
![]() |
5.100.545 | ![]() |
Rise from the grave | Upon use, spawns a friendly Bony or an orbital bone for each enemy killed in the current room. | 2 |
![]() |
5.100.550 | ![]() |
It feels cursed | While held, causes multiple Mom's Foots to come down and stomp on Isaac. One of two parts necessary to create Mom's Shovel. | 4 |
![]() |
5.100.504 | ![]() |
Friendly fly | Spawns a stationary fly turret that fires tears at nearby enemies. | 0 |
![]() |
5.100.482 | ![]() |
Change | Transforms Isaac into a random character and removes the last item collected. | 0 |
![]() |
5.100.480 | ![]() |
Gain more friends! | Doubles Isaac's Blue Flies and Blue Spiders, or spawns one if Isaac has none. Converts pickups in the current room into Blue Flies or Blue Spiders. | 2 |
![]() |
5.100.521 | ![]() |
Allow 6 weeks for delivery | Upon use, makes a random item from a Shop, Devil deal, or Black Market free. | 2 |
![]() |
5.100.485 | ![]() |
50/50 | Spawns a penny and has a 50% chance to double all items and pickups in the room. If the effect fails, the items and pickups disappear. | 1 |
![]() |
5.100.489 | ![]() |
Reroll forever | ![]() ![]() |
1 |
![]() |
5.100.476 | ![]() |
What will it be? | Duplicates a random pickup in the room. | 2 |
![]() |
5.100.481 | ![]() |
109 | Displaces enemy sprites for the current room, randomly increases one stat and decreases another. | 0 |
![]() |
5.100.510 | ![]() |
Unleash the power! | Spawns Delirium as a random friendly boss that fights for Isaac. | 1 |
![]() |
5.100.486 | ![]() |
I feel numb... | Hurts Isaac without depleting health, activating any items that trigger upon taking damage. | 1 |
![]() |
5.100.490 | ![]() |
... | Spawns two item pedestals then is consumed. Begins with no charges. | 3 |
![]() |
5.100.483 | ![]() |
BOOOOOOOOOM! | Damages all enemies and destroys all obstacles. The effect occurs every time a new room is entered for the rest of the floor. Opens doors to the floor's Secret and Super Secret Rooms. | 3 |
![]() |
5.100.488 | ![]() |
Waggles a finger | Grants a random item effect for the current room. | 0 |
![]() |
5.100.552 | ![]() |
Lost but not forgotten | Spawns a trapdoor that leads to the next floor upon activation. Unlocks The Forgotten when used on a mound of dirt that appears in ![]() |
4 |
![]() |
5.100.523 | ![]() |
Pack and unpack | If the box is empty, picks up all items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room. | 1 |
![]() |
5.100.527 | ![]() |
Caaan do! | Summons a controllable ghost that can perform various tasks depending on what it targets. | 3 |
![]() |
5.100.515 | ![]() |
Wrapped up nice for you! | Upon use, spawns a random item from the current room's item pool, with a chance to spawn A Lump of Coal or The Poop instead. | 3 |
![]() |
5.100.478 | ![]() |
Stop! | Freezes all enemies until a fire button is pressed. | 1 |
![]() |
5.100.475 | ![]() |
My last resort | Kills all enemies in the room, then kills Isaac three seconds later. | 0 |
![]() |
5.100.487 | ![]() |
A pound of flesh | Removes a heart container, increases damage and range, and grants a Cube of Meat. | 3 |
![]() |
5.100.536 | ![]() |
He demands a sacrifice | Sacrifices up to 2 familiars and spawns an item from the Devil Room pool for each familiar sacrificed. Converts all friendly spiders and flies into coins. | 2 |
![]() |
5.100.507 | ![]() |
More blood! | Damages all enemies in the room. Has a chance to drop a half red heart or half soul heart if an enemy is hit. | 2 |
![]() |
5.100.479 | ![]() |
Trinket melter! | Consumes Isaac's currently held trinket and applies its effect permanently. | 3 |
![]() |
5.100.516 | ![]() |
Sprinkles. | Upon use, spawns a sprinkler that rotates and fires tears. | 2 |
![]() |
5.100.522 | ![]() |
Power of the mind | Upon use, for the next two seconds, any enemy shots that come near Isaac are held in place. After the charge is depleted, they are fired back as tears. | 1 |
![]() |
5.100.477 | ![]() |
Consume | Consumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades. | 4 |
![]() |
5.100.484 | ![]() |
I can't believe it's not Butter Bean! | Isaac farts, sending out rock waves. | 0 |
![]() |
5.100.706 | ![]() |
Come forth from the depths | Destroys all items in the room and gives Isaac a unique attack fly familiar for each item destroyed. | 4 |
![]() |
5.100.585 | ![]() |
A sacred offering | Spawns three soul hearts and two angel room items. Must be charged by picking up 6 soul hearts. | 2 |
![]() |
5.100.722 | ![]() |
Repent | Chains down the nearest enemy for 5 seconds, preventing them from acting. | 2 |
![]() |
5.100.710 | ![]() |
Make your destiny | Collects and holds up to 8 pickups. Holding the activate button crafts them into a passive item, with the power level based on the quality of pickups used. | 3 |
![]() |
5.100.704 | ![]() |
Rip and tear | Causes Isaac to go berserk for 5 seconds, greatly increasing his speed, tears, and damage, but restricting him to using a melee weapon instead of his tears. This item charges by dealing damage to enemies instead of clearing rooms. | 3 |
![]() |
5.100.584 | ![]() |
Spiritual companionship | On use, spawns an orbital Wisp familiar that fires spectral tears but can be destroyed. Also becomes a passive item that causes other active items to spawn themed Wisps. | 3 |
![]() |
5.100.474 | ![]() |
You broke it! | Begins with no charges and turns into ![]() ![]() |
0 |
![]() |
5.100.263 | ![]() |
Rune mimic | Has the same effect as the rune or soul stone currently held by Isaac. | 2 |
![]() |
5.100.577 | ![]() |
A king's fortune... but at what cost? | Spawns a sword above Isaac's head, which doubles all item pedestals. After Isaac takes damage, the sword can randomly fall at any point, instantly killing him. | 2 |
![]() |
5.100.705 | ![]() |
One with the shadows | Makes Isaac invulnerable and intangible for one second. When the effect ends, all enemies Isaac ran through take damage and Isaac temporarily gains +1 damage for each one. | 2 |
![]() |
5.100.628 | ![]() |
Where am I? | Takes Isaac to an abandoned and expanded version of Home, which has one copy of every item in the game. After taking an item, Isaac returns to the room he used Death Certificate in. | 4 |
![]() |
5.100.729 | ![]() |
Chuck away! | Throws Isaac's head, which is still able to fire tears at the spot it lands. Reactivating the item or stepping on the head reattaches it. | 2 |
![]() |
5.100.638 | ![]() |
Erase thy enemy | Throws an eraser that instantly kills the first monster it hits, and prevents that monster from spawning for the rest of the run. Can only be used once per floor. | 2 |
![]() |
5.100.703 | ![]() |
Lost brother | Swaps between the current character and Esau Jr., who has +2 flat damage and flight. Characters have independent items and health. Dying as either character ends the run. | 2 |
![]() |
5.100.609 | ![]() |
??? | Rerolls all items in the room. Each item has a chance to disappear instead. | 2 |
![]() |
5.100.720 | ![]() |
Anything is possible | Spawns certain pickups based on how many charges it has. If fully charged, instead has one of many unique effects. | 2 |
![]() |
5.100.711 | ![]() |
Life and death | Switch characters between Tainted Lazarus and Dead Tainted Lazarus. | 3 |
![]() |
5.100.557 | ![]() |
Reusable fortunes | Gives Isaac a fortune, soul heart, tarot card, or trinket. | 2 |
![]() |
5.100.578 | ![]() |
Party time! | Creates a large pool of yellow creep beneath Isaac. | 2 |
![]() |
5.100.687 | ![]() |
Best friends forever! | Spawns a random friendly monster that mimics Isaac's movements and attacks. | 3 |
![]() |
5.100.728 | ![]() |
Demonic gestation | Spawns a demon familiar that's attached to Isaac and moves and fires in the direction Isaac shoots, using Isaac's damage, tears, range, shotspeed, and special tear effects. | 2 |
![]() |
5.100.622 | ![]() |
In the beginning | Removes all of Isaac's items and pickups and takes him to a unique bedroom with some pickups and chests and a trapdoor to the next floor. For every item Isaac lost, he gets to take an item from a set of three. | 2 |
![]() |
5.100.555 | ![]() |
Pain from gain | Spends five coins to increase Isaac's damage by 1.2 for the current room. | 2 |
![]() |
5.100.715 | ![]() |
Saved for later | Exclusive to Tainted ???. Allows him to save one poop bomb for later, allowing him to gather more over time. | 0 |
![]() |
5.100.685 | ![]() |
Your faith grows | Spawns random wisps that shoot various tears, block shots, and deal contact damage. The number of wisps spawned increases every time the jar is used. | 2 |
![]() |
5.100.719 | ![]() |
Portable shop | Spawns a random shop item/pickup. | 3 |
![]() |
5.100.611 | ![]() |
Hear my pain | Makes Isaac shout, damaging and pushing nearby enemies. The shout gets stronger the more charges the item has. Can also be charged by taking damage. | 2 |
![]() |
5.100.712 | ![]() |
Item summoner | Spawns the ghost of a random passive item, which orbits Isaac but can be destroyed. While the ghost is alive, Isaac gains that item's effects. | 3 |
![]() |
5.100.642 | ![]() |
All your desires fulfilled | Consumes one heart container or two soul hearts to spawn an item and give Isaac a broken heart container that can never be filled. If Magic Skin isn't being held after being used, it is very likely to replace any future items. | 2 |
![]() |
5.100.631 | ![]() |
Slice but no dice | Splits all enemies in the room into two smaller versions of themselves with much less health. | 1 |
![]() |
5.100.625 | ![]() |
I'm a big boy now! | Gigantifies Isaac for 30 seconds, increasing damage and range while lowering tears, granting invulnerability, and allowing Isaac to crush enemies and obstacles he walks on. The effect persists between rooms. | 4 |
![]() |
5.100.604 | ![]() |
Mother's strength | Lets Isaac pick up and throw rocks, TNT, poops, and other obstacles. | 2 |
![]() |
5.100.650 | ![]() |
Play time! | Summons the boss Baby Plum to fight for Isaac in the current room. | 2 |
![]() |
5.100.636 | ![]() |
Time to start over | Brings Isaac back to the first floor of a new run, retaining all of his items. | 4 |
![]() |
5.100.714 | ![]() |
Come back | Retrieves the Forgotten's body from any distance. Only available as the ![]() ![]() |
0 |
![]() |
5.100.580 | ![]() |
Explore the other side | Creates a new room adjacent to a viable wall, indicated by the outline of a door. These rooms have a chance to be various special rooms. | 3 |
![]() |
5.100.623 | ![]() |
Open your enemies | Adds 5 keys on pickup. Allows Isaac to throw his keys to deal damage to enemies, destroy obstacles, and open doors. | 1 |
![]() |
5.100.655 | ![]() |
Let it rip! | When used, gives Isaac +0.5 speed and greatly increases the rotation speed of Isaac's orbitals for 3 seconds. Gives Isaac a spinning top orbital that blocks enemy shots and deals contact damage to enemies while held. | 1 |
![]() |
5.100.723 | ![]() |
-1 | Transforms all items in the room by decreasing their internal ID number. | 4 |
![]() |
5.100.635 | ![]() |
Bait and switch | Passively spawns a familiar that moves in the direction Isaac shoots. On use, Isaac swaps places with the familiar. | 1 |
![]() |
5.100.556 | ![]() |
Temporary demon form | Grants ![]() |
2 |
![]() |
5.100.713 | ![]() |
Return | Holding down the fire button converts hearts into familiars that fire tears but can be destroyed. Activating converts the familiars back into hearts. | 3 |
![]() |
5.100.709 | ![]() |
Angel breaker | Allows Isaac to dash into and pick up enemies, then slam them into the ground to deal damage and create rock waves that damage nearby enemies and destroy obstacles. | 3 |
![]() |
5.100.605 | ![]() |
Plop! | Summons a Peeper familiar for the current room, which leaves a trail of red creep. | 0 |
![]() |
5.100.640 | ![]() |
Unleash their sorrow | Spews a stream of damaging flame. Gains Soul Charges each time an enemy dies, which are used to fuel the urn. | 3 |
![]() |
5.100.653 | ![]() |
Begone! | While held, non-ghost enemies leave behind small, red ghosts on death; using the item causes the ghosts to explode, dealing damage to nearby enemies. Stronger enemies leave behind stronger ghosts that create more powerful explosions. | 3 |
![]() |
5.100.582 | ![]() |
Tears up. A mind changing experience! | Increases fire rate, decreases speed, and distorts the screen. All effects become more pronounced with repeated use, and wear off by clearing rooms. | 1 |
![]() |
5.100.639 | ![]() |
Gross! | Gives Isaac a Rotten Heart. | 3 |
Passive Collectibles
An unlimited amount of passive collectibles can be held at a time, and the effects they grant are permanent. Their effects are vast and diverse, from simple stat and health increases to completely changing the way Isaac's tears behave.
Name | ID | Icon | Quote | Description | ![]() |
---|---|---|---|---|---|
???'s Only Friend | 5.100.320 | ![]() |
Controlled friend | Spawns a controllable familiar that deals 37.5 damage per second on touch. It can be moved using the shooting directional keys | 2 |
<3 | 5.100.15 | ![]() |
HP up | Grants Isaac one Red Heart container and fully restores Isaac's health. | 2 |
1up! | 5.100.11 | ![]() |
Extra life | Gives Isaac an extra life. Upon death, he will respawn in the previous room with full health and lose the 1up!. | 2 |
20/20 | 5.100.245 | ![]() |
Double shot | Isaac fires two tears at once, one from each eye. | 4 |
3 Dollar Bill | 5.100.191 | ![]() |
Rainbow tears | ![]() ![]() |
2 |
9 Volt | 5.100.116 | ![]() |
Quicker charge | Reduces the charge of any activated item by 1. Any 1 charge items instead have timed recharges. | 2 |
A Dollar | 5.100.18 | ![]() |
$$$ | Gives Isaac 99 coins. | 2 |
A Lump of Coal | 5.100.132 | ![]() |
My Xmas Present | The more distance tears travel, the more damage they will do. | 3 |
A Quarter | 5.100.74 | ![]() |
+25 coins | Adds 25 to Isaac's coin count, capping at 99. | 2 |
A Snack | 5.100.346 | ![]() |
HP up | ![]()
|
1 |
Abaddon | 5.100.230 | ![]() |
Evil + DMG up + fear shot | ![]() ![]() |
4 |
Abel | 5.100.188 | ![]() |
Mirrored buddy | Spawns a familiar that mirrors Isaac's movements and shoots in the opposite direction. | 0 |
Anemic | 5.100.214 | ![]() |
Toxic blood | +5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room. | 0 |
Ankh | 5.100.161 | ![]() |
Eternal life? | Upon death, the player will respawn as ![]() |
2 |
Anti-Gravity | 5.100.222 | ![]() |
Antigravity tears + tears up | -2 Tear Delay. Tears float in position until firing ceases, after which they will fly off in the direction they were shot in. | 3 |
Aquarius | 5.100.308 | ![]() |
Trail of tears | A trail of blue creep is left behind Isaac, which damages enemies. | 0 |
Aries | 5.100.300 | ![]() |
Ramming speed | +0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage. | 1 |
Ball of Bandages | 5.100.207 | ![]() |
Gotta lick 'em all! | Spawns an orbital familiar that blocks enemy shots, dealing 105 damage per second. Collecting additional copies gives it the ability to shoot charm tears, then chase enemies, then increases the damage. | 2 |
Ball of Tar | 5.100.231 | ![]() |
Sticky feet... | Adds a chance to shoot slowing tears. Isaac leaves a trail of slowing creep behind as he moves, impeding enemies' speed. | 2 |
BBF | 5.100.272 | ![]() |
Big Beautiful Fly | Spawns a familiar that flies around the room in a zig-zag pattern and explodes on contact with an enemy. Respawns after ten seconds. | 1 |
Best Bud | 5.100.274 | ![]() |
Sworn protector | When hit, spawns a quickly orbiting attack fly similar to ![]() |
0 |
BFFS! | 5.100.247 | ![]() |
Your Friends Rule! | Increases the size and effectiveness of most familiars. | 2 |
Big Fan | 5.100.279 | ![]() |
Fat protector | Spawns a large orbital familiar that blocks enemy shots and deals 30 damage per second to enemies. | 2 |
Black Candle | 5.100.260 | ![]() |
Curse immunity + evil up | Prevents curses. Grants one Black Heart. Increases the chance for a Devil or Angel Room to appear. | 3 |
Black Lotus | 5.100.226 | ![]() |
HP up x3! | Grants one Red Heart, one Soul Heart, and one Black Heart. | 2 |
Blood Bag | 5.100.119 | ![]() |
HP up | Grants one Red Heart container, restores 5 Red Hearts, and increases speed by 0.3. | 2 |
Blood Clot | 5.100.254 | ![]() |
DMG + range up | Tears fired from the left eye have +1 flat damage, +5 range, and +0.5 tear height. | 2 |
Blood of the Martyr | 5.100.7 | ![]() |
DMG up | Increases Damage by 1, and turns Isaac's tears into blood tears. | 3 |
Bloody Lust | 5.100.157 | ![]() |
RAGE! | Increases Isaac's damage whenever he takes damage, up to six times. The bonus resets when entering a new floor. | 3 |
Blue Cap | 5.100.342 | ![]() |
HP + tears up + shot speed down | ![]()
|
3 |
Blue Map | 5.100.246 | ![]() |
Secrets | Shows Secret and Super Secret Room locations on the map. | 2 |
Bob's Brain | 5.100.273 | ![]() |
Explosive thoughts | Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds. | 1 |
Bob's Curse | 5.100.140 | ![]() |
+5 poison bombs | Gives 5 bombs and grants Isaac's bombs a poison effect. | 1 |
Bobby-Bomb | 5.100.125 | ![]() |
Homing bombs! | +5 bombs. Bombs gain a homing effect, slowly moving towards the nearest enemy. | 2 |
Bogo Bombs | 5.100.250 | ![]() |
1+1 boom! | All Bomb pickups become Double Bombs. | 1 |
Bomb Bag | 5.100.131 | ![]() |
Gives bombs | Spawns a familiar that drops a bomb every 3 rooms. | 2 |
Boom! | 5.100.19 | ![]() |
10 bombs | Grants 10 bombs. | 0 |
Box | 5.100.198 | ![]() |
Stuff | Spawns various pickups: 1 coin, 1 key, 1 bomb, 1 Red Heart, 1 card/rune, 1 pill and 1 trinket. | 1 |
Breakfast | 5.100.25 | ![]() |
HP up | Grants Isaac one full Red Heart container. | 1 |
Brimstone | 5.100.118 | ![]() |
Blood laser barrage | Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period. | 4 |
Broken Watch | 5.100.337 | ![]() |
I think it's broken | Chance upon entering a room to slow down or speed up every enemy and their attacks. The chance to slow enemies is quite higher than the chance to speed them up. | 1 |
Brother Bobby | 5.100.8 | ![]() |
Friends 'till the end | A familiar that follows Isaac around shooting normal tears. | 0 |
Bucket of Lard | 5.100.129 | ![]() |
HP up | Grants two empty Red Heart containers and heals Isaac by half a Red Heart, but decreases speed by 0.2. | 1 |
Bum Friend | 5.100.144 | ![]() |
He's greedy | Spawns a familiar that picks up coins for himself, giving random pickups in return. Does not spawn collectibles. | 0 |
Butt Bombs | 5.100.209 | ![]() |
Toxic blast +5 bombs | +5 bombs. Bombs now cloud up the screen, briefly damaging and confusing all enemies. | 2 |
Caffeine Pill | 5.100.340 | ![]() |
Speed up + size down | Grants +0.3 speed, reduces character size and gives a random pill. | 1 |
Cain's Other Eye | 5.100.319 | ![]() |
Near-sighted friend | Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to The Peeper and shoots normal tears in the same direction as Isaac. | 0 |
Cancer | 5.100.301 | ![]() |
HP up + you feel protected | Adds 3 Soul Hearts. Grants The Wafer effect for the current room upon taking damage. | 3 |
Capricorn | 5.100.307 | ![]() |
All stats up | Increases health, damage, speed, and range, lowers tear delay, and gives one coin, bomb, and key. | 3 |
Cat-O-Nine-Tails | 5.100.165 | ![]() |
Shot speed + damage up | +1 damage, +0.23 shot speed. | 3 |
Celtic Cross | 5.100.162 | ![]() |
You feel blessed | Grants a chance to trigger the ![]() |
1 |
Ceremonial Robes | 5.100.216 | ![]() |
Sin up | Grants 3 Black Hearts, and +1 damage. | 3 |
Champion Belt | 5.100.208 | ![]() |
DMG + Challenge Up | Increases damage, but also increases the chance of champion enemies appearing. | 3 |
Charm of the Vampire | 5.100.62 | ![]() |
Kills heal | Heals Isaac for half of a Red Heart for every 13 enemies killed. | 0 |
Chemical Peel | 5.100.154 | ![]() |
DMG up | Tears fired from the left eye have +2 flat damage. | 1 |
Chocolate Milk | 5.100.69 | ![]() |
Charge shots | Grants charged tears that deal greater damage when fully charged. | 3 |
Contract From Below | 5.100.241 | ![]() |
Wealth... but at what cost? | Doubles the number of most room clear awards, but reduces the overall chance of getting one by 1/3. | 3 |
Cricket's Body | 5.100.224 | ![]() |
Bursting shots + tears up | Grants -1 tear delay and reduces range. When tears hit an object or deplete their range, they spawn 4 smaller tears, whose range and damage scale with Isaac's. | 3 |
Cricket's Head | 5.100.4 | ![]() |
DMG up | Increases damage by 0.5, and multiplies it by 1.5x. | 4 |
Cube of Meat | 5.100.73 | ![]() |
Gotta meat 'em all! | Spawns an orbital familiar that blocks enemy shots, dealing 105 damage per second. Collecting additional copies grants it the ability to shoot, then chase enemies, then increases the damage. | 2 |
Cupid's Arrow | 5.100.48 | ![]() |
Piercing shots | Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them. | 3 |
Cursed Eye | 5.100.316 | ![]() |
Cursed charge shot | Grants charged tears that can be fired in a tight burst. Getting hit while charging will teleport Isaac to another room. | 0 |
Daddy Longlegs | 5.100.170 | ![]() |
Daddy's love | Daddy Long Legs' shadow follows Isaac and occasionally stomps enemies for 40 damage total. | 3 |
Dark Bum | 5.100.278 | ![]() |
He wants to take your life | Spawns a familiar that follows Isaac around and collects Red Hearts for himself. For every 1½ Red Hearts collected, Dark Bum will give a Soul Heart, a hostile Spider, a friendly Blue Spider, ![]() |
4 |
Dark Matter | 5.100.259 | ![]() |
Fear shot | +1 damage, adds a chance to shoot fear tears. | 3 |
Dead Bird | 5.100.117 | ![]() |
Protective buddy | After Isaac takes damage, spawns a flying familiar that chases enemies for the current room, dealing ~5 damage per second. | 0 |
Dead Cat | 5.100.81 | ![]() |
9 lives | Sets Isaac's Red Heart containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container. | 3 |
Dead Dove | 5.100.185 | ![]() |
Flight + spectral tears | Grants spectral tears and flight. | 3 |
Dead Onion | 5.100.336 | ![]() |
Toxic aura tears | Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed. | 3 |
Death's Touch | 5.100.237 | ![]() |
Penetrative shot + damage up | +1.5 damage, -0.3 tears. Tears are replaced with large piercing scythes. | 3 |
Demon Baby | 5.100.113 | ![]() |
Auto-turret friend | Spawns a familiar that follows Isaac and automatically fires at enemies in its reach. | 2 |
Dessert | 5.100.24 | ![]() |
HP Up | Grants one full Red Heart container. | 1 |
Dinner | 5.100.23 | ![]() |
HP Up | Grants one full Red Heart container. ![]() |
1 |
Distant Admiration | 5.100.57 | ![]() |
Attack fly | Spawns an attack fly that circles further out than ![]() ![]() |
2 |
Dr. Fetus | 5.100.52 | ![]() |
??? | Tears are replaced by bombs that benefit from bomb-enhancing effects and slide for a fixed time after being fired. | 4 |
Dry Baby | 5.100.265 | ![]() |
Immortal Friend | Spawns a familiar that follows Isaac around and blocks enemy projectiles. Upon blocking a shot, it has a chance of triggering ![]() |
3 |
E Coli | 5.100.236 | ![]() |
Turdy touch | Enemies that touch Isaac are changed into poop. | 1 |
Epic Fetus | 5.100.168 | ![]() |
On-demand air strike | Isaac's tears are replaced with guided missiles, like those used by the ![]() |
4 |
Eve's Mascara | 5.100.310 | ![]() |
Shot speed down + DMG up | Doubles damage, halves tears stat, and greatly reduces shot speed. | 1 |
Experimental Treatment | 5.100.240 | ![]() |
Some stats up, some stats down | Randomly increases and decreases some of the character's stats. | 1 |
Fanny Pack | 5.100.204 | ![]() |
It's filled with goodies! | Has a chance to drop a random pickup when Isaac takes damage. | 1 |
Fate | 5.100.179 | ![]() |
Flight eternal | Grants flight and one Eternal Heart. | 3 |
Fire Mind | 5.100.257 | ![]() |
Flaming tears | Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion. | 2 |
Forever Alone | 5.100.128 | ![]() |
Attack fly | Spawns an attack fly that orbits a long distance from Isaac, dealing 30 damage per second. | 1 |
Gemini | 5.100.318 | ![]() |
Conjoined friend | Spawns a conjoined familiar which chases enemies close to Isaac, dealing ~8 damage per second. | 1 |
Ghost Baby | 5.100.163 | ![]() |
Spectral buddy | Spawns a familiar that follows Isaac around and fires spectral tears. | 1 |
Gimpy | 5.100.225 | ![]() |
Sweet Suffering | Gives chance of spawning a Soul Heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed. | 2 |
Gnawed Leaf | 5.100.210 | ![]() |
Unbreakable | After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots. | 1 |
Goat Head | 5.100.215 | ![]() |
He accepts your offering | A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II. | 3 |
Godhead | 5.100.331 | ![]() |
God tears | Grants homing tears with a damaging halo. +0.5 damage, -0.3 tears, +1.2 range, -0.3 shot speed, +0.8 tear height. | 4 |
Growth Hormones | 5.100.70 | ![]() |
Speed + DMG up | +1 damage, +0.4 speed. | 3 |
Guardian Angel | 5.100.112 | ![]() |
Extra protection | Spawns an orbital familiar that blocks enemy shots, deals 105 damage per second to enemies, and increases the speed of all orbital familiars. | 2 |
Guillotine | 5.100.206 | ![]() |
An out-of-body experience | Isaac's head is removed from his body and floats around him as an orbital. Gives +1 damage and grants -1 tear delay. | 3 |
Guppy's Collar | 5.100.212 | ![]() |
Eternal Life? | Grants a permanent 50% chance to respawn with 1/2 of a Red Heart after death. | 2 |
Guppy's Hair Ball | 5.100.187 | ![]() |
Swing it | Spawns a familiar that loosely follows behind Isaac, which blocks shots can be swung like a flail to damage enemies. Grows bigger by killing enemies. | 1 |
Guppy's Tail | 5.100.134 | ![]() |
Cursed? | Room clear awards have a 1/3 chance of being replaced with a chest and a 1/3 chance being replaced with nothing. | 2 |
Habit | 5.100.156 | ![]() |
Item Martyr | When Isaac is hit, his active item gains 1 room's worth of charge. | 3 |
Halo of Flies | 5.100.10 | ![]() |
Projectile protection | Spawns two Pretty Flies that block enemy shots and deal contact damage to flies. | 3 |
Harlequin Baby | 5.100.167 | ![]() |
Double shot buddy | Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern. | 1 |
Headless Baby | 5.100.269 | ![]() |
Bloody Friend | Spawns a familiar that follows Isaac, leaving blood creep on the ground. | 1 |
Hive Mind | 5.100.248 | ![]() |
Giant spiders and flies | Increases the size of Blue Spiders and Blue Flies and doubles the amount of damage they deal. | 2 |
Holy Grail | 5.100.184 | ![]() |
Flight + HP up | Grants flight and one Red Heart container. | 3 |
Holy Mantle | 5.100.313 | ![]() |
Holy shield | Upon entering a room, grants a shield that negates the first damage taken. | 4 |
Holy Water | 5.100.178 | ![]() |
Splash! | ![]() ![]() |
0 |
Hot Bombs | 5.100.256 | ![]() |
Burning blast +5 bombs | Grants 5 bombs. Isaac's bombs leave behind fire that damages enemies upon contact. | 1 |
Humbling Bundle | 5.100.203 | ![]() |
1+1 free 4evar! | ![]() ![]() |
3 |
Infamy | 5.100.242 | ![]() |
Blocks damage... sometimes | Chance to block projectiles coming from any direction. | 2 |
Infestation | 5.100.148 | ![]() |
Fly revenge | 1-3 Blue Flies randomly spawn every time Isaac gets hit. | 0 |
Infestation 2 | 5.100.234 | ![]() |
Infestation shot | Spawns allied Blue Spiders from killed enemies. | 4 |
Ipecac | 5.100.149 | ![]() |
Explosive shots | Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth. | 4 |
Iron Bar | 5.100.201 | ![]() |
Concussive tears | Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly. | 3 |
Isaac's Heart | 5.100.276 | ![]() |
Protect It | Isaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt. | 0 |
Jesus Juice | 5.100.197 | ![]() |
Damage + range up | +0.5 damage, +0.25 range, +0.5 tear height. | 2 |
Judas' Shadow | 5.100.311 | ![]() |
Sweet revenge | Adds an extra life; upon death, it respawns Isaac as ![]() |
4 |
Juicy Sack | 5.100.266 | ![]() |
Sticky babies | Spawns a familiar that follows Isaac and drips a trail of slow creep, spawning 1-2 Blue Spiders after each room. | 2 |
Key Piece 1 | 5.100.238 | ![]() |
??? | Combined with Key Piece 2, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan. | 0 |
Key Piece 2 | 5.100.239 | ![]() |
??? | Combined with Key Piece 1, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan. | 0 |
Latch Key | 5.100.343 | ![]() |
Luck up | Grants 1 Soul Heart and +1 luck. Spawns 2 Keys. | 2 |
Lazarus' Rags | 5.100.332 | ![]() |
Eternal Life? | Upon dying, resurrect as ![]() |
1 |
Leech | 5.100.270 | ![]() |
Blood sucker | Spawns a leech familiar that chases enemies, dealing ~3 damage per second. Heals a Half Red Heart whenever Leech kills an enemy. | 1 |
Leo | 5.100.302 | ![]() |
Stompy | Isaac can destroy rocks by walking into them. | 1 |
Libra | 5.100.304 | ![]() |
You Feel Balanced | Gives 6 coins, 6 bombs, and 6 keys and balances out all attributes. | 1 |
Lil Brimstone | 5.100.275 | ![]() |
Evil Friend | Grants a familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting. | 3 |
Lil Haunt | 5.100.277 | ![]() |
Fear him | Spawns a familiar that chases down enemies, dealing 4 damage per second and inflicting fear. | 1 |
Little Baggy | 5.100.252 | ![]() |
Extra pill room | Isaac can hold 2 pills at once and all cards are replaced by pills. | 1 |
Little C.H.A.D. | 5.100.96 | ![]() |
Gives kisses | Spawns a familiar who drops a Half Red Heart every 3 rooms. | 2 |
Little Chubby | 5.100.88 | ![]() |
Attack Buddy | Spawns a charger familiar that charges forward and deals contact damage to any enemies in its path. | 1 |
Little Gish | 5.100.99 | ![]() |
Sticky friend | Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed. | 2 |
Little Steven | 5.100.100 | ![]() |
Psychic friend | Spawns a familiar who follows Isaac around and fires homing tears. | 1 |
Loki's Horns | 5.100.87 | ![]() |
Cross Tears | Gives a random chance for projectiles to fire in all 4 cardinal directions. | 1 |
Lord of the Pit | 5.100.82 | ![]() |
Demon wings | Grants flight and +0.3 speed. | 3 |
Lost Contact | 5.100.213 | ![]() |
Shielded tears | Isaac's tears can hit and destroy enemy projectiles. -0.16 shot speed. | 2 |
Lucky Foot | 5.100.46 | ![]() |
Luck up | +1 luck. Increases chance of winning Shell Games and Fortune Tellers (independent from the luck stat).![]() |
2 |
Lunch | 5.100.22 | ![]() |
HP Up | Grants one full Red Heart container. ![]() |
1 |
Maggy's Bow | 5.100.312 | ![]() |
HP up + you feel healthy | Gives one Red Heart container and doubles the healing provided by Red Hearts. | 2 |
Magic 8 Ball | 5.100.194 | ![]() |
Shot speed up | +0.16 shot speed, spawns a random tarot card. | 1 |
Magic Mushroom | 5.100.12 | ![]() |
All Stats Up! | Makes Isaac bigger. Adds one Red Heart container, +0.3 damage, x1.5 damage multiplier, +5.25 range, and +0.3 speed. Restores all health on pickup. | 4 |
Magic Scab | 5.100.253 | ![]() |
HP + Luck up | Grants one full Red Heart container, +1 luck. | 2 |
Magneto | 5.100.53 | ![]() |
Item snatcher | Pulls pickups towards Isaac. | 1 |
Match Book | 5.100.344 | ![]() |
Evil up | Grants Isaac one Black Heart, Spawns two or three Bombs. | 1 |
MEAT! | 5.100.193 | ![]() |
DMG + HP up | Grants one full Red Heart container, +0.3 damage. | 2 |
Midas' Touch | 5.100.202 | ![]() |
Golden touch | Enemies that touch Isaac are temporarily petrified and turn to gold. Any enemy killed while in this state will drop coins. | 2 |
Mini Mush | 5.100.71 | ![]() |
Speed + range up | Decreases Isaac's size, making him less likely to be hit. +0.3 speed, +1.5 tear height, -4.25 range (effective range is increased). | 2 |
Missing No. | 5.100.258 | ![]() |
Syntax error | Randomizes all passive items and stats upon pickup and at the start of each succeeding floor. | 2 |
Missing Page 2 | 5.100.262 | ![]() |
Evil up. Your enemies will pay! | Grants one Black Heart. Upon taking damage that reduces Isaac's health to one heart or less, deals damage to all enemies in the room. ![]() ![]() |
0 |
Mitre | 5.100.173 | ![]() |
Blessing of purity | Grants a chance of converting any Red Heart pickups into Soul Hearts instead. | 3 |
Mom's Coin Purse | 5.100.195 | ![]() |
What's all this...? | Spawns 4 random pills near Isaac. | 1 |
Mom's Contacts | 5.100.110 | ![]() |
Freeze effect | +0.25 range. Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. | 3 |
Mom's Eye | 5.100.55 | ![]() |
Eye in the back of your head | Allows Isaac to fire tears from the back of his head. | 1 |
Mom's Eyeshadow | 5.100.200 | ![]() |
Charm tears | Tears have a chance to charm enemies. | 1 |
Mom's Heels | 5.100.30 | ![]() |
Range up | +5.25 range, +0.5 tear height. ![]() |
1 |
Mom's Key | 5.100.199 | ![]() |
Better chest loot +2 keys | Adds 2 keys. Chests will drop additional pickups. | 3 |
Mom's Knife | 5.100.114 | ![]() |
Stab stab stab | Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power. | 4 |
Mom's Lipstick | 5.100.31 | ![]() |
Range up | +5.25 range, +0.5 tear height. ![]() |
1 |
Mom's Perfume | 5.100.228 | ![]() |
Fear shot | Adds a chance to shoot fear tears and decreases tear delay by 1. | 2 |
Mom's Purse | 5.100.139 | ![]() |
More trinket room | Allows Isaac to hold 1 additional trinket. | 3 |
Mom's Underwear | 5.100.29 | ![]() |
Range up | +5.25 range, +0.5 tear height. ![]() |
1 |
Mom's Wig | 5.100.217 | ![]() |
You feel itchy... | Adds a chance to spawn Blue Spiders when firing tears. Restores 1 red heart. | 3 |
Money = Power | 5.100.109 | ![]() |
$$$ = DMG | Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins. | 3 |
Mongo Baby | 5.100.322 | ![]() |
Mongo Friend | Spawns a familiar that copies the tears of Isaac's other familiars. | 2 |
Monstro's Lung | 5.100.229 | ![]() |
Chargeable burst attack | Increases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro. | 2 |
Mr. Mega | 5.100.106 | ![]() |
Bigger boom | Grants 5 bombs, and makes all dropped bombs larger, which have an increased blast radius and increased damage. | 2 |
Mutant Spider | 5.100.153 | ![]() |
Quad shot | Grants quadruple shot but decreases tears. | 3 |
My Reflection | 5.100.5 | ![]() |
Boomerang tears | Gives Isaac's tears a boomerang effect. +1.5 range, +1 tear height, x1.6 shot speed multiplier. | 0 |
Mysterious Liquid | 5.100.317 | ![]() |
Toxic Splash Damage | Tears leave a small, short lasting pool of creep on impact or when their range is depleted. | 1 |
Mystery Sack | 5.100.271 | ![]() |
? | Spawns a familiar that drops a Heart, coin, bomb, or key every 5-6 rooms. | 2 |
Number One | 5.100.6 | ![]() |
Tears up | +1.5 tears, -17.62 range | 2 |
Odd Mushroom | 5.100.121 | ![]() |
DMG + HP up, Speed down. | Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear height, and -0.1 speed. | 2 |
Odd Mushroom | 5.100.120 | ![]() |
Fire rate up | +1.7 tears, +0.3 speed, slightly reduces damage. | 3 |
Old Bandage | 5.100.219 | ![]() |
HP up | Grants an empty Red Heart container. Adds a chance of dropping a Red Heart after taking damage. | 2 |
Ouija Board | 5.100.115 | ![]() |
Spectral tears | Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them. | 2 |
Pageant Boy | 5.100.141 | ![]() |
Ultimate grand supreme | Spawns seven random coins around Isaac. | 0 |
Pentagram | 5.100.51 | ![]() |
DMG up | +1 damage, increases Devil Room / Angel Room chance by 10%. | 3 |
PHD | 5.100.75 | ![]() |
Better pills | Converts all bad pills into good pills, spawns one pill pickup, and identifies all pills. Restores two Red Hearts and increases the payout of Blood Donation Machines. | 2 |
Piggy Bank | 5.100.227 | ![]() |
My life savings | Gives 3 pennies on pick-up. Every time Isaac is damaged, he will drop one additional penny. | 1 |
Pisces | 5.100.309 | ![]() |
Tears up + knock-back shots | -1 Tear Delay, adds knock-back shots and increases tear size. | 2 |
Placenta | 5.100.218 | ![]() |
HP up + regen | Grants one full Red Heart container, and a chance to regenerate a Half Red Heart of health every minute of gameplay. | 2 |
Polyphemus | 5.100.169 | ![]() |
Mega Tears | Isaac fires huge tears that deal massive damage but fire rate is greatly decreased. If a tear kills an enemy, the tear travels on with any leftover damage. | 4 |
Proptosis | 5.100.261 | ![]() |
Short range mega tears | Tears start out massive with high damage, and then shrink down and become weaker over a short range. | 4 |
Punching Bag | 5.100.281 | ![]() |
Scape Goat | Spawns a Mulligan familiar that wanders randomly. Enemies will attack the Mulligan if it's closer. | 1 |
Pyro | 5.100.190 | ![]() |
99 bombs | Grants 99 bombs. | 3 |
Pyromaniac | 5.100.223 | ![]() |
It hurts so good +5 Bombs | Isaac heals 1 Red Heart instead of taking damage from an explosive source. Adds 5 bombs. | 4 |
Rainbow Baby | 5.100.174 | ![]() |
Random buddy | Spawns a familiar that follows Isaac around and fires tears with random effects. | 1 |
Raw Liver | 5.100.16 | ![]() |
HP up | Grants 2 Red Heart containers and completely restores health. | 2 |
Robo-Baby | 5.100.95 | ![]() |
Friends 'till the bbbbzzzt | Spawns a familiar that shoots ![]() |
1 |
Robo-Baby 2.0 | 5.100.267 | ![]() |
We worked out all the kinks | Fires lasers at any enemy in its line of sight and moves based on the direction Isaac is firing tears. | 0 |
Roid Rage | 5.100.14 | ![]() |
Speed and range up | +0.6 speed, +5.25 range, +0.5 tear height. | 2 |
Rosary | 5.100.72 | ![]() |
Tears + faith up | Adds 3 Soul Hearts. The Bible will appear in any item pool.![]() |
1 |
Rotten Baby | 5.100.268 | ![]() |
Infested friend | Spawns a familiar that spawns a Blue Fly when Isaac shoots. It can only have one Fly at a time. | 3 |
Rotten Meat | 5.100.26 | ![]() |
HP up | Adds one full Red Heart container. | 1 |
Rubber Cement | 5.100.221 | ![]() |
Bouncing tears | Tears bounce off walls, enemies, and environmental objects. | 3 |
Sack of Pennies | 5.100.94 | ![]() |
Gives money | Spawns a familiar that drops a coin every 2 rooms. | 1 |
Sacred Heart | 5.100.182 | ![]() |
Homing shots + DMG up | Grants homing tears, x2.3 damage multiplier, +1 flat damage, +4.125 range, +0.75 tear height, -0.4 tears, -0.25 shot speed, a red Heart Container and replenishes all Red Hearts. | 4 |
Sacrificial Dagger | 5.100.172 | ![]() |
My fate protects me | Spawns a dagger orbital familiar, dealing 225 damage per second and blocking enemy shots. | 3 |
Sad Bombs | 5.100.220 | ![]() |
Tear blast +5 bombs | +5 Bombs. Upon exploding, bombs shoot 10 tears around them, affected by tear modifiers. | 3 |
Safety Pin | 5.100.339 | ![]() |
Evil + range + shot speed up | Grants one Black Heart, +5.25 range, +0.5 tear height, +0.16 shot speed. | 1 |
Sagittarius | 5.100.306 | ![]() |
Penetrative shot + speed up | Increases speed by +0.2 and grants piercing tears. | 3 |
Samson's Chains | 5.100.321 | ![]() |
The ol' ball and chain | Attaches a ball and chain to Isaac that pulls behind him that damages enemies, blocks shots, and destroys most obstacles. | 1 |
Scapular | 5.100.142 | ![]() |
Pray for a miracle | Once per room, when Isaac is reduced to his last half heart, he is granted one Soul Heart. | 2 |
Scorpio | 5.100.305 | ![]() |
Poison tears | Grants poison tears, which deal damage over time when inflicted. | 2 |
Screw | 5.100.255 | ![]() |
Tears and shot speed up. | +0.5 tears, +0.2 shot speed. | 3 |
Sharp Plug | 5.100.205 | ![]() |
Charge with blood | Damages Isaac in exchange for fully recharging Isaac's current activated item. | 1 |
Sissy Longlegs | 5.100.280 | ![]() |
She loves you | Spawns a familiar that wanders randomly, occasionally spawning Blue Spiders. | 1 |
Sister Maggy | 5.100.67 | ![]() |
Friends 'till the end | Spawns a familiar that follows Isaac around shooting normal tears. | 0 |
Skatole | 5.100.9 | ![]() |
Fly love | Flies become harmless or less dangerous depending on the type. | 0 |
Skeleton Key | 5.100.17 | ![]() |
99 keys | Gives Isaac 99 keys. | 3 |
Smart Fly | 5.100.264 | ![]() |
Revenge fly | Spawns an orbital familiar that blocks enemy shots. Upon taking damage, the familiar will pursue enemies for the rest of the room, dealing 22.5 damage per second. | 3 |
SMB Super Fan | 5.100.189 | ![]() |
All stats up | +1 Red Heart container, +0.3 damage, +0.2 tears, +0.2 speed, +0.5 range, +1 tear height. Fully restores all red hearts. | 3 |
Soy Milk | 5.100.330 | ![]() |
DMG Down + Tears Way Up | Tears are smaller and do much less damage, but fire in very rapid succession. | 2 |
Speed Ball | 5.100.143 | ![]() |
Speed + shot speed up | +0.3 speed, +0.2 shot speed. | 2 |
Spelunker Hat | 5.100.91 | ![]() |
See-through doors | Reveals type of adjacent rooms, including location for Secret Rooms and Super Secret Rooms. | 2 |
Spider Bite | 5.100.89 | ![]() |
Slow effect | Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them. | 2 |
Spiderbaby | 5.100.211 | ![]() |
Spider revenge | When hit, spawns up to 2 Blue Spiders. | 1 |
Spirit of the Night | 5.100.159 | ![]() |
Scary | Grants spectral tears and flight. | 3 |
Spoon Bender | 5.100.3 | ![]() |
Homing shots | Grants Isaac homing tears. | 3 |
Squeezy | 5.100.196 | ![]() |
Tears up | Increases tears by 0.4, spawns 2 Soul Hearts. | 3 |
Starter Deck | 5.100.251 | ![]() |
Extra card room | Isaac can hold 2 cards at once and all pills are replaced by cards. | 2 |
Steam Sale | 5.100.64 | ![]() |
50% off | Reduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup. | 2 |
Stem Cells | 5.100.176 | ![]() |
HP up | Grants one full Red Heart container and +0.16 shot speed. | 1 |
Steven | 5.100.50 | ![]() |
DMG up | Increases damage by 1. | 3 |
Stigmata | 5.100.138 | ![]() |
DMG + HP up | Increases damage, and adds 1 heart container. | 2 |
Stop Watch | 5.100.232 | ![]() |
Let's slow this down a bit... | ![]() ![]() ![]() |
4 |
Strange Attractor | 5.100.315 | ![]() |
Magnetic tears | Pickups, trinkets, and monsters are magnetically attracted to Isaac's tears. | 0 |
Super Bandage | 5.100.92 | ![]() |
+2 hearts | Grants one full Red Heart container and 2 Soul Hearts. | 2 |
Synthoil | 5.100.345 | ![]() |
DMG up + range | +1 damage, +5.25 range, +0.5 tear height. | 3 |
Taurus | 5.100.299 | ![]() |
Speed down + rage is building | -0.3 Speed. Isaac builds speed while in a room with enemies. At max speed, he gains the ![]() |
1 |
Tech.5 | 5.100.244 | ![]() |
It's still being tested... | Isaac occasionally fires an unlimited range piercing laser alongside his normal tears. The laser can glitch, mimicking the effects of certain items and trinkets. | 3 |
Technology | 5.100.68 | ![]() |
Laser tears | Replaces tears with a piercing laser with unlimited range. | 3 |
Technology 2 | 5.100.152 | ![]() |
Laser | Decreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously. | 2 |
The Battery | 5.100.63 | ![]() |
Stores energy | Activated collectibles can be "overcharged" to allow for an additional use. | 2 |
The Belt | 5.100.28 | ![]() |
Speed up | Increases speed by 0.3. | 2 |
The Black Bean | 5.100.180 | ![]() |
Toot on touch | When taking damage, Isaac farts, causing poison damage to all enemies in range. | 0 |
The Body | 5.100.334 | ![]() |
I feel all | Adds 3 Red Heart containers. | 3 |
The Common Cold | 5.100.103 | ![]() |
Poison Damage | Adds a chance to shoot poison tears, dealing damage over time when inflicted. | 1 |
The Compass | 5.100.21 | ![]() |
The end is near | Reveals all special rooms (except secret rooms of any kind). | 2 |
The Halo | 5.100.101 | ![]() |
All stats up | Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear height. | 2 |
The Inner Eye | 5.100.2 | ![]() |
Triple shot | Grants triple shot but decreases tears. | 2 |
The Ladder | 5.100.60 | ![]() |
Building bridges | Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections. | 1 |
The Ludovico Technique | 5.100.329 | ![]() |
Controlled Tears | Instead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy. | 3 |
The Mark | 5.100.79 | ![]() |
DMG + speed up | Grants one Soul Heart, +1 damage, and +0.2 speed. | 3 |
The Mind | 5.100.333 | ![]() |
I know all | Reveals the entire map, including all special rooms and Secret Rooms. | 3 |
The Mulligan | 5.100.151 | ![]() |
They grow inside | Tears have a 1/6 chance of spawning allied Blue Flies when they hit an enemy. | 3 |
The Negative | 5.100.328 | ![]() |
Fate Chosen | If Isaac has half a red heart or no red hearts after taking damage, all enemies in the room take significant damage. Allows entrance into the ![]() ![]() ![]() |
1 |
The Pact | 5.100.80 | ![]() |
DMG + Tears UP | Grants two ![]() ![]() |
3 |
The Parasite | 5.100.104 | ![]() |
Split Shot | Isaac's tears split in two when they hit something. | 2 |
The Peeper | 5.100.155 | ![]() |
Plop! | Spawns a familiar that floats slowly around the room on a zig-zag pattern, damaging enemies it passes through. | 0 |
The Polaroid | 5.100.327 | ![]() |
Fate Chosen | If Isaac has half a red heart or no red hearts after taking damage, he gains a shield that nullifies all types of damage for 5 seconds. Allows entrance into ![]() ![]() ![]() |
2 |
The Relic | 5.100.98 | ![]() |
Soul generator | Spawns a cross familiar that drops a Soul Heart every 5-6 rooms. | 4 |
The Sad Onion | 5.100.1 | ![]() |
Tears up | Increases tears by 0.7. | 3 |
The Small Rock | 5.100.90 | ![]() |
DMG up | Increases damage by 1, increases tears by 0.2, and decreases speed by 0.2. | 3 |
The Soul | 5.100.335 | ![]() |
I am all | Grants two Soul Hearts. Isaac gains a pulsing aura that repels enemies and projectiles. | 3 |
The Virus | 5.100.13 | ![]() |
Poison touch | Inflicts poison to enemies who make contact with Isaac. Speed down. ![]() |
0 |
The Wafer | 5.100.108 | ![]() |
Damage resistance | All sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead. | 4 |
There's Options | 5.100.249 | ![]() |
More options | There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear. | 3 |
Thunder Thighs | 5.100.314 | ![]() |
HP up + speed down + you feel stompy | Destroys rocks upon contact with Isaac. Adds one Red Heart container and lowers Speed. | 1 |
Tiny Planet | 5.100.233 | ![]() |
Orbiting tears + range up | Range up and makes shot tears revolve around Isaac until they drop. | 0 |
Toothpicks | 5.100.183 | ![]() |
Tears + shot speed up | +0.7 tears, +0.16 shot speed. | 3 |
Torn Photo | 5.100.341 | ![]() |
Tears + shot speed up | +0.7 tears, +0.16 shot speed. | 3 |
Tough Love | 5.100.150 | ![]() |
Tooth shot | Adds a chance to shoot a tooth instead of a tear, which deals greater damage than regular tears. | 3 |
Transcendence | 5.100.20 | ![]() |
We all float down here... | Grants flight. | 3 |
Treasure Map | 5.100.54 | ![]() |
Full visible map | Reveals all rooms for every floor. However, it does not reveal icons or secret rooms. | 2 |
Trinity Shield | 5.100.243 | ![]() |
You feel guarded | Isaac gains a shield that protects him from enemy shots. It aims in the direction Isaac fires from. | 3 |
Virgo | 5.100.303 | ![]() |
You feel refreshed and protected | Adds a chance to give a shield that nullifies all incoming damage for 10 seconds upon taking damage. Also converts bad pills into good pills. | 2 |
Whore of Babylon | 5.100.122 | ![]() |
Curse up | Grants +1.5 damage and +0.3 speed whenever Isaac has half a red heart or less (one red heart for Eve), ignoring any Soul or Black Hearts. | 2 |
Wire Coat Hanger | 5.100.32 | ![]() |
Tears up | Increases tears by 0.7. | 3 |
Wooden Spoon | 5.100.27 | ![]() |
Speed up | Increases speed by 0.3. | 1 |
X-Ray Vision | 5.100.76 | ![]() |
I've seen everything | Reveals and opens all Secret Room and Super Secret Room entrances. | 2 |
![]() |
5.100.359 | ![]() |
Stick it to 'em! | +1.5 Damage Up. Replaces Isaac's tears with nails, which have increased knockback. | 3 |
![]() |
5.100.408 | ![]() |
Call to the void | When Isaac takes damage, a black ring briefly appears around him, dealing damage to all nearby enemies. | 2 |
![]() |
5.100.391 | ![]() |
Turn your enemy | Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac. | 0 |
![]() |
5.100.438 | ![]() |
Tears up | Grants one Soul Heart, +0.75 tears and decreases Isaac's size. | 3 |
![]() |
5.100.420 | ![]() |
Spin the black circle! | Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it. | 1 |
![]() |
5.100.353 | ![]() |
Explosive blast! | +5 bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects player-spawned Troll Bombs. | 2 |
![]() |
5.100.385 | ![]() |
Bumbo want coin! | Spawns a beggar familiar which picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo follows enemies and gains contact damage. | 1 |
![]() |
5.100.377 | ![]() |
Spider love | Spider enemies no longer target or deal contact damage to Isaac. | 1 |
![]() |
5.100.412 | ![]() |
Feed them hate | After taking damage a certain amount of times, a permanent demonic familiar spawns. | 2 |
![]() |
5.100.356 | ![]() |
Active power up | Causes Isaac's activated item to activate twice on each use. | 3 |
![]() |
5.100.387 | ![]() |
Peace be with you | Spawns a familiar which creates a circular aura that slows down enemies and enemy shots inside. | 3 |
![]() |
5.100.402 | ![]() |
!!! | Drops 1-6 random pickups on the floor. Causes items to be chosen from random item pools. | 3 |
![]() |
5.100.372 | ![]() |
Bbbzzzzzt! | Spawns a familiar that occasionally drops a Lil' Battery, gives an activate item charge, or petrifies all enemies in the room. | 3 |
![]() |
5.100.423 | ![]() |
Protect me from myself | Surrounds Isaac with a large white halo that occasionally deals Isaac's tear damage to enemies inside it, and can convert enemy shots into friendly homing tears. | 1 |
![]() |
5.100.369 | ![]() |
Transcendent tears | Grants spectral tears and increases range. Tears travel through walls and appear at the opposite side of the room. | 2 |
![]() |
5.100.354 | ![]() |
Don't swallow the prize! | Grants one full Red Heart container and drops a random trinket. | 2 |
![]() |
5.100.415 | ![]() |
The untainted gain power | +2 soul hearts. While Isaac has no empty red hearts, grants 2x damage, +5.25 range, and -0.3 shot speed. Regardless of health, the crown deactivates for the current room when Isaac takes damage. | 4 |
![]() |
5.100.371 | ![]() |
Embrace chaos | Upon taking damage, spawns six Troll Bombs around the room similar to the ![]() |
1 |
![]() |
5.100.373 | ![]() |
Accuracy brings power! | Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot. | 3 |
![]() |
5.100.416 | ![]() |
More money! | ![]() ![]() |
2 |
![]() |
5.100.381 | ![]() |
Your future shines brighter | +0.7 tears up. Grants a random item at the start of the next run. | 3 |
![]() |
5.100.409 | ![]() |
I reward an empty vessel | Grants two Black Hearts. While Isaac has no red hearts, grants flight and periodically grants an invincibility shield for a few seconds. | 2 |
![]() |
5.100.368 | ![]() |
Intensifying tears | Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount. | 1 |
![]() |
5.100.410 | ![]() |
Eye shot! | While firing tears, Isaac has a chance to fire an eye across the screen with a very slow shot speed, which will fire tears of its own in the same direction as Isaac. The eye will be destroyed if it comes into contact with an enemy or obstacle. | 2 |
![]() |
5.100.401 | ![]() |
Sticky bomb shot! | Isaac's tears have a chance to stick to enemies and explode. | 1 |
![]() |
5.100.404 | ![]() |
He farts! | Spawns a familiar that follows Isaac and blocks enemy shots. If a shot hits Farting Baby, it has a chance to fart, which Charms, Poisons, or knocks back nearby enemies. | 1 |
![]() |
5.100.361 | ![]() |
Your fate beside you | A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage. | 2 |
![]() |
5.100.364 | ![]() |
Friendly fly | Spawns a white attack fly that orbits somewhere between ![]() ![]() |
1 |
![]() |
5.100.418 | ![]() |
Rainbow effects! | Isaac's tears gain a random effect that changes every shot. | 2 |
![]() |
5.100.405 | ![]() |
Double tap glitch | ![]() ![]() |
0 |
![]() |
5.100.432 | ![]() |
Prize bombs! | +5 bombs. Bombs have a chance to drop random pickups or charm enemies when they explode. | 2 |
![]() |
5.100.398 | ![]() |
Shrink shot | Tears have a chance to shrink enemies, making them run away from Isaac. Shrunk enemies can be crushed and killed by walking over them. | 1 |
![]() |
5.100.429 | ![]() |
Penny tears! | Isaac's tears become coins and now have a chance to drop Pennies on the floor upon successfully hitting an enemy. | 2 |
![]() |
5.100.374 | ![]() |
Holy death shot | Adds a chance to fire holy tears, which will create a damaging light beam in the area if they hit an enemy. | 3 |
![]() |
5.100.375 | ![]() |
Blast resistance | A host familiar that sits on Isaac's head and has a random chance to block enemy shots and retaliate with 3 tears. Grants immunity to explosions. | 3 |
![]() |
5.100.413 | ![]() |
Feed them love | Upon picking up a certain amount of health, spawn a permanent angelic familiar. | 1 |
![]() |
5.100.360 | ![]() |
Dark friend | Spawns a demonic familiar that shoots tears identical to Isaac's in terms of damage, tears, and tear effects. | 4 |
![]() |
5.100.388 | ![]() |
He wants your keys! | Spawns a familiar that follows Isaac and collects Keys for himself, giving random Chests in return. | 0 |
![]() |
5.100.440 | ![]() |
Matt's kidney stone | Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. The burst of tears also includes a kidney stone, which deals a lot of damage. | 1 |
![]() |
5.100.362 | ![]() |
What's in the box? | Spawns a chest familiar that spawns a random pickup (25% chance) or trinket (10% chance) upon clearing a room. | 2 |
![]() |
5.100.384 | ![]() |
A gurd of your own! | A Gurdy Jr. familiar that charges up while Isaac is firing, bouncing around the room when released and dealing contact damage based on its speed. | 1 |
![]() |
5.100.435 | ![]() |
4-way buddy! | Spawns a Loki familiar that follows Isaac and fires 4 tears in a cross pattern. | 1 |
![]() |
5.100.365 | ![]() |
Lost protector | Spawns fly familiar that moves in a straight line and circles around the first wall or obstacle it hits, dealing 105 damage per second on contact. | 0 |
![]() |
5.100.411 | ![]() |
Their blood brings rage! | Isaac's damage increases for the current room each time he kills an enemy. | 3 |
![]() |
5.100.394 | ![]() |
Directed tears | Isaac will automatically fire tears directed at a red target on the ground. The target can be moved with tear controls. | 0 |
![]() |
5.100.399 | ![]() |
Consume thy enemy! | Charged by firing for 2.5 seconds and when released, creates a black ring around Isaac that rapidly deals damage. ![]() |
4 |
![]() |
5.100.436 | ![]() |
Don't cry over it... | Spawns a glass familiar that spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the current room. | 1 |
![]() |
5.100.355 | ![]() |
Range + luck up | +1.25 range, +0.5 tear height, +1 luck. | 2 |
![]() |
5.100.414 | ![]() |
There's options | Two items spawn in every Treasure Room. Only one can be taken; the other will disappear. | 3 |
![]() |
5.100.370 | ![]() |
Range + tears up | +0.7 tears, +5.25 range, +0.5 tear height, spawns 3 random types of Hearts on the floor when picked up. | 3 |
![]() |
5.100.431 | ![]() |
ydduB Buddy | Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed. | 1 |
![]() |
5.100.433 | ![]() |
Me! And my shaaaadow! | Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black friendly Charger that will attack enemies. The Charger will be killed if it is damaged too much. | 0 |
![]() |
5.100.425 | ![]() |
Scared of the dark? | A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots. | 2 |
![]() |
5.100.378 | ![]() |
Uh oh... | Continuously firing tears for three seconds causes Isaac to drop a Butt Bomb, which damages and confuses all enemies in the room when it explodes. | 2 |
![]() |
5.100.426 | ![]() |
Follows my every move... | Spawns a familiar that follows Isaac's movements on a 3 second delay and deals contact damage to enemies. | 0 |
![]() |
5.100.430 | ![]() |
Turret follower | Spawns a familiar that follows Isaac's movements on a 3 second delay, firing tears at nearby enemies. | 1 |
![]() |
5.100.380 | ![]() |
Money talks | +5 coins. Turns doors that require a single key into doors which need a coin to enter instead. | 2 |
![]() |
5.100.428 | ![]() |
You feel cozy | Grants 4 Soul Hearts and fully restores Isaac's health. | 2 |
![]() |
5.100.379 | ![]() |
Wide shot | Gives Isaac spectral tears and gives his tears a wide arc shape, increasing their size. | 2 |
![]() |
5.100.407 | ![]() |
Aura stat boost | Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range. | 2 |
![]() |
5.100.376 | ![]() |
Never ending stores! | Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode. | 3 |
![]() |
5.100.389 | ![]() |
Rune generator | Spawns a familiar that drops a random rune every 5-6 rooms. | 3 |
![]() |
5.100.424 | ![]() |
More sacks! | Coins, bombs, keys, cards, runes and batteries have a chance to become sacks. | 3 |
![]() |
5.100.366 | ![]() |
We put bombs in your bombs! | Adds 5 bombs. Isaac's bombs explode into 2-4 tiny bombs. | 1 |
![]() |
5.100.390 | ![]() |
Sworn friend | Spawns an angel familiar which follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed. | 3 |
![]() |
5.100.393 | ![]() |
The kiss of death | Tears have a chance to apply a poison effect to enemies. Isaac poisons enemies on contact. Poisoned enemies have a chance to drop a black heart when killed. | 4 |
![]() |
5.100.400 | ![]() |
Your destiny | In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2x his tear damage, and occasionally inflicts fear. | 1 |
![]() |
5.100.403 | ![]() |
Mod buddy! | Displays Isaac's tear damage and enemy health bars. Spawns a familiar that wanders around and inflicts random status effects on enemies it touches. Can spawn a Lil' Battery/Blue spider upon clearing a room. | 1 |
![]() |
5.100.367 | ![]() |
Egg sack bombs! | +5 bombs. Bombs stick to enemies and spawn 2-4 Blue Spiders if they kill an enemy. | 1 |
![]() |
5.100.417 | ![]() |
Damage booster | Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5x tear damage multiplier. | 3 |
![]() |
5.100.363 | ![]() |
Protective friend | Spawns an orbital familiar which does 105 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room it drops an Eternal Heart. | 3 |
![]() |
5.100.395 | ![]() |
Laser ring tears | Tears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the size of the ring. | 4 |
![]() |
5.100.358 | ![]() |
Double wiz shot! | Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U a Wizard? pill. Isaac's tears also travel above all obstacles. | 1 |
![]() |
5.100.350 | ![]() |
Mass poison | Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground. | 3 |
![]() |
5.100.397 | ![]() |
Control your tears | Increases tears, range, and shot speed. Isaac emits a beam from his face that his tears follow along. | 2 |
![]() |
5.100.392 | ![]() |
The heavens will change you | Gives Isaac a random zodiac item effect that changes every floor. | 1 |
![]() |
5.100.526 | ![]() |
Lil harbingers! | Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts. | 2 |
![]() |
5.100.491 | ![]() |
Pills pills pills! | Spawns a familiar that drops a random pill every 3 rooms. Upon using a pill, all enemies in the room are poisoned. | 2 |
![]() |
5.100.493 | ![]() |
Panic = power | Increases damage based on how many empty Red Heart containers Isaac has. | 1 |
![]() |
5.100.465 | ![]() |
360 tears! | +0.35 tears up. Allows Isaac to fire tears diagonally. | 2 |
![]() |
5.100.528 | ![]() |
Eclipsed by the moon | Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears. | 3 |
![]() |
5.100.511 | ![]() |
He's violent | Spawns a fly familiar that orbits around a random enemy and deals 30 damage per second to enemies it comes in contact with. | 1 |
![]() |
5.100.443 | ![]() |
Trick or treat? | Increases tears. Adds a chance to fire a high-damage razor blade. | 3 |
![]() |
5.100.506 | ![]() |
Watch your back! | Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac. | 1 |
![]() |
5.100.458 | ![]() |
What's in there? | Drops a random trinket. Grants a second trinket slot. | 3 |
![]() |
5.100.473 | ![]() |
Chub chub | Spawns a familiar that follows Isaac and charges across the room when Isaac fires, blocking shots and dealing 40.5 damage per second on contact. | 1 |
![]() |
5.100.535 | ![]() |
You feel Safe | Grants one Soul Heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears. | 1 |
![]() |
5.100.509 | ![]() |
Bloody friend | Spawns an orbital familiar that deals 30 damage per second and fires a randomly angled tear every 2 seconds. | 1 |
![]() |
5.100.513 | ![]() |
Party time! | Increases damage by a flat 0.1 and grants a Soul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop. | 2 |
![]() |
5.100.549 | ![]() |
Everything hurts | Replaces all Red Hearts with 6 empty Bone Hearts. Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a tears up. | 3 |
![]() |
5.100.514 | ![]() |
Lag! | Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals. | 1 |
![]() |
5.100.551 | ![]() |
It feels cursed | One of two parts necessary to create Mom's Shovel. | 4 |
![]() |
5.100.518 | ![]() |
What could it be?! | Spawns a familiar with a random tear effect. The familiar is randomized at the start of each floor. | 2 |
![]() |
5.100.497 | ![]() |
Camo kid | Isaac becomes camouflaged at the beginning of each room. Until he shoots, all non-boss enemies will be confused. | 0 |
![]() |
5.100.453 | ![]() |
Bone tears! | Increases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle. | 2 |
![]() |
5.100.457 | ![]() |
Hard headed! | Grants a Soul Heart. Gives Isaac a chance to ignore any damage taken. | 2 |
![]() |
5.100.466 | ![]() |
Outbreak! | The first enemy killed in a room explodes and poisons nearby enemies. Poisoned enemies will also explode upon death. | 2 |
![]() |
5.100.455 | ![]() |
I remember this... | +1.5 range, Drops a Lucky Penny. | 2 |
![]() |
5.100.546 | ![]() |
Father's blessing | Creates a ring of light around Isaac that petrifies enemies in contact. | 3 |
![]() |
5.100.442 | ![]() |
Loss is power | When at exactly one Red Heart, grants +0.75 tears, +1.5 range, +1 tear height, +0.2 shot speed. | 1 |
![]() |
5.100.446 | ![]() |
Halitosis | While firing, Isaac gains a green aura that poisons nearby enemies. | 1 |
![]() |
5.100.530 | ![]() |
Just hope you're not next... | Grants a pickup or stat upgrade if all enemies in a room are killed in the order they are marked. | 2 |
![]() |
5.100.469 | ![]() |
:( | Spawns a familiar that leaves a trail of creep that damages enemies at 6 damage per second. Has a chance to spawn damaging beams of light onto enemies that touch the cloud. | 1 |
![]() |
5.100.547 | ![]() |
Tears up + you feel empty | Grants one Bone Heart, +0.7 tears, spawns a Mysterious Paper. | 2 |
![]() |
5.100.445 | ![]() |
Bark at the moon! | +0.3 damage, +0.1 speed. Plays a howl or bark sound when entering a room with undiscovered Secret Rooms or Crawl Spaces. | 1 |
![]() |
5.100.498 | ![]() |
You feel very balanced | Whenever a Devil or Angel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered. | 1 |
![]() |
5.100.499 | ![]() |
Peace be with you | An Angel Room door will always spawn after every boss fight, excluding the first floor and floors after ![]() ![]() |
3 |
![]() |
5.100.496 | ![]() |
Needle shot | Adds a chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles. | 3 |
![]() |
5.100.462 | ![]() |
Possessed tears! | Grants piercing tears. After piercing one enemy, tears start homing and deal double damage. | 3 |
![]() |
5.100.450 | ![]() |
Gold tears! | Every 20 tears, Isaac loses 1 coin and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins. | 2 |
![]() |
5.100.517 | ![]() |
Rapid bomb drops | Grants 7 bombs and allows bombs to be placed rapidly. | 1 |
![]() |
5.100.467 | ![]() |
Watch where you point that! | Spawns a finger familiar that points at enemies, dealing scaling damage. | 1 |
![]() |
5.100.540 | ![]() |
Skipping tears | Tears bounce off the floor, creating splashes. Splashes deal 25% of Isaac's tear damage to all enemies in a small area. | 2 |
![]() |
5.100.495 | ![]() |
Flame tears | Adds a chance to shoot a fire that damages enemies and remains in place until it deals enough damage or the room is left. | 2 |
![]() |
5.100.460 | ![]() |
Blind tears! | Adds a chance to shoot tears that confuse enemies for an extremely long time. | 2 |
![]() |
5.100.464 | ![]() |
A gift from above | Grants 2 Soul Hearts and modifies drops from Champion monsters based on certain conditions. ![]() |
1 |
![]() |
5.100.501 | ![]() |
Money = health! | Grants a Red Heart container for every 25 coins Isaac has. | 1 |
![]() |
5.100.531 | ![]() |
I'm seeing red... | Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay. | 2 |
![]() |
5.100.543 | ![]() |
Portable sanctuary | Spawns a white poop familiar, which turns into a white poop when Isaac is hurt. White poop has an aura that halves tear delay and can block enemy shots. | 1 |
![]() |
5.100.470 | ![]() |
Lil hush! | Spawns a Hush familiar that bounces diagonally around the room and deals contact damage. While firing tears, it stops moving. | 0 |
![]() |
5.100.494 | ![]() |
Electric tears | Tears fire sparks of electricity in random directions upon hitting an obstacle or enemy. | 2 |
![]() |
5.100.548 | ![]() |
Fetch! | Spawns a familiar that flies through the room while firing, dealing a flat 7 contact damage to enemies retrieving pickups. | 1 |
![]() |
5.100.520 | ![]() |
Bloody recharge | Grants an active item charge every 15 enemies killed. | 3 |
![]() |
5.100.472 | ![]() |
Hail to the king baby | Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, other familiars stop moving. | 0 |
![]() |
5.100.532 | ![]() |
Feed them! | Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage. | 2 |
![]() |
5.100.502 | ![]() |
Creep shots | Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep. | 1 |
![]() |
5.100.444 | ![]() |
He's a bleeder! | After every 15 tears fired, Isaac will fire a high-damage cluster of tears. | 3 |
![]() |
5.100.525 | ![]() |
You're tearing me apart! | Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots. | 1 |
![]() |
5.100.519 | ![]() |
Delirious friend | Grants a familiar that transforms into another random familiar every 10 seconds. | 2 |
![]() |
5.100.471 | ![]() |
Ain't he cute? | Spawns a familiar that fires clusters of tears. Must be charged before shooting. | 2 |
![]() |
5.100.537 | ![]() |
Puking buddy | Drops a random pill, and spawns a familiar that charges up and fires creep. Using pills changes the creep type. | 1 |
![]() |
5.100.447 | ![]() |
Crying makes me toot | Constantly shooting causes Isaac to release gas clouds that can be pushed by his tears and damage nearby enemies. | 0 |
![]() |
5.100.503 | ![]() |
Big brother is watching | ![]() ![]() |
3 |
![]() |
5.100.538 | ![]() |
Choking hazard | Spawns 3 random trinkets, 5% chance to swallow held trinket after taking damage, gaining its effect permanently. | 2 |
![]() |
5.100.541 | ![]() |
HP up? | Grants one bone heart and spawns three red heart pickups. | 1 |
![]() |
5.100.449 | ![]() |
It itches... | Grants one Soul Heart. Enemy shots have a chance to be reflected at the shooter as confusing tears. | 1 |
![]() |
5.100.456 | ![]() |
HP up | Grants one full Red Heart container. | 1 |
![]() |
5.100.508 | ![]() |
It's sharp! | Spawns an orbiting razor that deals contact damage and inflicts bleeding on enemies, causing them to slowly take damage over time. | 1 |
![]() |
5.100.539 | ![]() |
Sacrificial insemination | Spawns an egg familiar, which cracks into a random friendly monster when Isaac is hurt. The egg regenerates upon entering a different room. | 1 |
![]() |
5.100.461 | ![]() |
Egg tears! | Adds a chance to fire an egg sack which creates slowing creep and spawns a Blue Fly or Blue Spider upon hitting an enemy. | 3 |
![]() |
5.100.544 | ![]() |
Stabbing time | Spawns a bone familiar that hovers back and forth in front of Isaac, dealing damage equal to Isaac's damage. | 2 |
![]() |
5.100.505 | ![]() |
Gotta catch em... | Upon entering a room with enemies in it, has a chance to spawn a random friendly enemy that persists across rooms. | 0 |
![]() |
5.100.454 | ![]() |
Hold me! | Allows Isaac to carry two cards, pills, or any combination of both. Spawns one random card, rune or pill. | 2 |
![]() |
5.100.529 | ![]() |
Eyeball tears! | Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle. | 2 |
![]() |
5.100.500 | ![]() |
Gives sacks | Spawns a familiar that drops a sack every 5-6 rooms cleared. | 3 |
![]() |
5.100.534 | ![]() |
Extra active item room | Allows Isaac to hold two active items. | 3 |
![]() |
5.100.468 | ![]() |
It follows | Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers. | 0 |
![]() |
5.100.448 | ![]() |
Blood and guts! | ![]() ![]() |
0 |
![]() |
5.100.459 | ![]() |
Booger tears! | Adds a chance to fire a booger that sticks to enemies and deals damage over time. | 3 |
![]() |
5.100.542 | ![]() |
Projectile shield | Spawns a bone familiar that circles around Isaac and reflects enemy shots. | 2 |
![]() |
5.100.463 | ![]() |
Acid tears! | +0.3 damage. Adds a chance to fire acidic tears which can destroy obstacles. | 2 |
![]() |
5.100.451 | ![]() |
I see the future | Drops a random card or rune. ![]() ![]() |
3 |
![]() |
5.100.524 | ![]() |
Static tears! | Connects Isaac's tears with electricity that can damage enemies. | 3 |
![]() |
5.100.533 | ![]() |
Smite thy enemy | Damage down. Tears are replaced with piercing white blasts of light that can damage the same enemy multiple times. | 2 |
![]() |
5.100.452 | ![]() |
I'm leaking... | Taking damage releases a ring of 10 high damage tears. | 2 |
![]() |
5.100.492 | ![]() |
Yo listen! | +1 luck. Spawns a fairy familiar that points out Secret Rooms, Crawl Space entrances, and tinted rocks. | 2 |
![]() |
5.100.559 | ![]() |
Zap! | Repeatedly zaps enemies that are close to Isaac. | 3 |
![]() |
5.100.554 | ![]() |
4me | Enemies near Isaac are afflicted with fear. | 2 |
![]() |
5.100.647 | ![]() |
Beat the juice out of them! | Active items don't charge when clearing rooms. Instead, they're charged by dealing damage to enemies. | 2 |
![]() |
5.100.564 | ![]() |
Tears + shot speed up | Gives Isaac +0.5 Tears and +0.2 Shot Speed. | 3 |
![]() |
5.100.672 | ![]() |
Blood money | Devil deals now cost coins, shop items now cost health, and consumables in shops are free but surrounded by spikes. | 1 |
![]() |
5.100.601 | ![]() |
Tears up, you feel forgiven | Increases tears and grants an Eternal Heart. Allows Angel Rooms to appear even if a Devil deal has been taken before. | 3 |
![]() |
5.100.641 | ![]() |
Spill your guts | Creates a chain of tears behind Isaac while in combat. | 2 |
![]() |
5.100.561 | ![]() |
DMG down + tears up + you feel nutty | Quadruples fire rate, with x0.3 damage multiplier. Tears are given random worm trinket effects. | 1 |
![]() |
5.100.677 | ![]() |
The true out-of-body experience! | Causes Isaac to turn into a ghost if he gets hit while in a room with enemies, giving him flight and spectral tears and blocking the next hit he takes. | 2 |
![]() |
5.100.699 | ![]() |
Ancient power | Isaac builds rage every time a room is cleared. After four rooms, fires a large ![]() |
3 |
![]() |
5.100.603 | ![]() |
Instant energy! | Recharges Isaac's currently held active item and drops 2-4 batteries. | 1 |
![]() |
5.100.690 | ![]() |
Bounce away! | Causes enemies to bounce off of Isaac, dealing damage to them if they hit and enemy or obstacle. Also gives Isaac the chance to deflect enemy shots. | 2 |
![]() |
5.100.664 | ![]() |
All you can eat | +1 red heart container and fully heals Isaac. Item pedestals cycle between their normal items and food, and collecting food grants a temporary damage boost and permanent bonuses to 2 stats. | 3 |
![]() |
5.100.610 | ![]() |
Fat buddy | The first time Isaac takes damage in a room, a familiar leaps on an enemy, dealing damage and releasing a rock wave. For the rest of the room, it chases enemies similar to ![]() |
1 |
![]() |
5.100.616 | ![]() |
It burns | Gives Isaac the chance to shoot fires alongside his regular tears that block enemy shots and deal damage to enemies that touch them. | 2 |
![]() |
5.100.619 | ![]() |
??? | Has a different effect for each character. | 2 |
![]() |
5.100.614 | ![]() |
Bloody blast + HP up | Grants a Red Heart container and restore 5 hearts. Bombs leave behind damaging red creep. Isaac can place bombs at the cost of half a heart if he doesn't have any. | 1 |
![]() |
5.100.569 | ![]() |
Bleed me dry | Stabs Isaac at the beginning of each floor, draining his red hearts. Increases damage and speed for the floor based on the amount drained. | 2 |
![]() |
5.100.565 | ![]() |
What a cute little thing! | Spawns a familiar that chases enemies. After killing enough enemies, it becomes more powerful and drops red hearts after killing enemies, but will also try to hurt Isaac. Attacking it returns it to normal. | 2 |
![]() |
5.100.695 | ![]() |
May your rage bring haste | When Isaac takes damage, he gains speed and tears for the rest of the floor. | 3 |
![]() |
5.100.607 | ![]() |
Messy friend | Gives Isaac a familiar that fires chaotic bursts of tears in all directions. | 1 |
![]() |
5.100.683 | ![]() |
Break your enemies | Enemies spawn floating bones on death, which block shots and damage/repel enemies that touch them. | 2 |
![]() |
5.100.624 | ![]() |
Collect them all! | Spawns 5 random cards. | 1 |
![]() |
5.100.629 | ![]() |
Defense drone | Spawns an orbiting fly familiar that fires shielded tears at incoming enemy projectiles. | 3 |
![]() |
5.100.646 | ![]() |
Demon blast +5 bombs | Gives Isaac +5 bombs and causes his bombs to fire ![]() |
3 |
![]() |
5.100.678 | ![]() |
Fetus shots | Switches control to a fetus that is attached via umbilical cord. The fetus has flight as well as all of Isaac's tear effects and stats. | 4 |
![]() |
5.100.671 | ![]() |
Power of love | Gives permanent stat boosts when Isaac heals with red heart pickups. | 2 |
![]() |
5.100.660 | ![]() |
A link to your future | Spawns two portals that each lead to either the Boss Room, Secret Room, or Treasure Room at the beginning of each floor. | 3 |
![]() |
5.100.644 | ![]() |
+1 to lowest stat | Increases Isaac's lowest stat and drops either 3 coins, 1 bomb, or 1 key depending on what Isaac has the least of. | 1 |
![]() |
5.100.675 | ![]() |
Shards of knowledge | Unlocks doors and reveals a random room on the map when Isaac takes damage. | 1 |
![]() |
5.100.652 | ![]() |
Kick it! | Spawns an ice cube familiar that slides around when walked into. It slows and deals contact damage, freezing monsters it kills. | 1 |
![]() |
5.100.668 | ![]() |
... | Begins the sequence to access Home. | 0 |
![]() |
5.100.576 | ![]() |
Filthy friends | Destroying poop spawns friendly Dips that follow Isaac and damage enemies. Destroying different types of poop spawns different Dips with special effects. | 2 |
![]() |
5.100.568 | ![]() |
Double tap shield | Double tapping a fire key creates a shield that pushes away enemies and reflects enemy projectiles and lasers. | 2 |
![]() |
5.100.633 | ![]() |
Ascended | Grants flight, +0.1 speed, +2 damage, and the ![]() |
0 |
![]() |
5.100.566 | ![]() |
Sweet dreams | During the transition between floors, Isaac's nightmare shows the floor's Treasure Room item and boss. Grants half a soul heart when entering a new floor. | 2 |
![]() |
5.100.700 | ![]() |
I can see see the future future future | When Isaac uses a card, pill, or rune, he also uses a copy of every card/pill/rune he used after picking up Echo Chamber. | 2 |
![]() |
5.100.676 | ![]() |
It multiplies | If Isaac has an empty heart container, another one is added at the start of each floor. | 2 |
![]() |
5.100.632 | ![]() |
Luck up + you feel protected | Increases luck by 2.0. | 1 |
![]() |
5.100.600 | ![]() |
Tears up | Lowers the tear delay in Isaac's left eye, causing his eyes to fire at different rates. | 3 |
![]() |
5.100.572 | ![]() |
DMG up + range up + controlled tears | Isaac's tears are now controlled mid-flight with tear controls. Also increases damage and range, but decreases shot speed. | 3 |
![]() |
5.100.558 | ![]() |
More eyes | Causes Isaac to occasionally extra fire tears in random directions while shooting. | 2 |
![]() |
5.100.654 | ![]() |
Worse pills + evil up | Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black Heart. | 2 |
![]() |
5.100.608 | ![]() |
Iced iced baby | Spawns a shooting familiar that has a chance to petrify enemies, and Freezes monsters upon killing them. | 2 |
![]() |
5.100.649 | ![]() |
Bouncy friend | Gives Isaac a miniature Baby Plum familiar that propels itself diagonally around the room, firing tears behind itself as it travels. | 1 |
![]() |
5.100.727 | ![]() |
Spooky blast +5 bombs | Gives Isaac 5 bombs and causes his bombs to spawn ghosts that deal contact damage to enemies and explode after 10 seconds. | 2 |
![]() |
5.100.658 | ![]() |
Micro friends | Causes Isaac to spawn micro-Isaacs when he takes damage, which chase and shoot at nearby enemies. | 1 |
![]() |
5.100.689 | ![]() |
????? | Before being picked up, item pedestals cycle between 5 random items. | 4 |
![]() |
5.100.665 | ![]() |
An eye for secrets | Shows the contents of Chests, Sacks, and Fire Places before they're opened. | 2 |
![]() |
5.100.694 | ![]() |
Eternal sorrow | Grants 3 broken hearts and +0.25 damage for every broken heart Isaac has. Every otherwise fatal hit will add 2 more until Isaac has nothing but broken hearts. | 3 |
![]() |
5.100.726 | ![]() |
Double tap sneeze | Double-tapping a fire button causes Isaac to sneeze blood, dealing damage to enemies in front of him. | 3 |
![]() |
5.100.684 | ![]() |
Out for blood | Enemies have a chance to spawn ghosts on death, which chase and deal contact damage to enemies and explode after a short time. | 3 |
![]() |
5.100.724 | ![]() |
Thick blooded | After taking damage from an enemy, launches a half or full red heart from Isaac that despawns after 1.5 seconds. | 3 |
![]() |
5.100.725 | ![]() |
Your stomach rumbles | Causes Isaac to throw poop, create buffing creep, or drop bombs while fighting enemies. | 2 |
![]() |
5.100.573 | ![]() |
Halo of tears | Adds one red heart container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him. | 3 |
![]() |
5.100.688 | ![]() |
Let him free | Upon death, Isaac respawns in the current room with half a heart left, a massive size down, and +0.2 speed. | 3 |
![]() |
5.100.701 | ![]() |
Buried memories | Spawns an Old Chest at the start of each floor. | 3 |
![]() |
5.100.560 | ![]() |
No it doesn't... | Releases a ring of tears and increases tears for the current room when Isaac takes damage. | 1 |
![]() |
5.100.594 | ![]() |
You're a gas giant! | +2 red Heart containers, -0.3 speed. Isaac builds speed while standing still, and releases poison gas clouds when he moves afterwards. | 3 |
![]() |
5.100.717 | ![]() |
Under a rock | Rocks and props spawn spiders over time while in a room with enemies, and spawn two blue spiders when destroyed. | 2 |
![]() |
5.100.716 | ![]() |
Spending power | Gives range, speed, or damage when buying things from a shop. Also spawns three coins and a key on pickup. | 3 |
![]() |
5.100.626 | ![]() |
??? | Combined with ![]() ![]() ![]() |
0 |
![]() |
5.100.627 | ![]() |
??? | Combined with ![]() ![]() ![]() |
0 |
![]() |
5.100.637 | ![]() |
They pack a punch! | Adds a chance to shoot a fist tear that has extremely high knockback and confuses enemies. | 3 |
![]() |
5.100.679 | ![]() |
Abyssal friend | Spawns a familiar that charges a miniature ![]() ![]() |
3 |
![]() |
5.100.615 | ![]() |
Puffy buddy | Gives Isaac a Dumpy familiar that, when it takes damage, pushes/stuns/poisons nearby enemies and flies in a random direction. | 0 |
![]() |
5.100.681 | ![]() |
It hungers | A familiar that flies forward, consuming pickups in its path. Each one will increase its size and damage and spawn a Blue Fly. Every four pickups, it opens a portal that leads to an unexplored room. | 1 |
![]() |
5.100.617 | ![]() |
Magnetizing tears | Gives Isaac the chance to fire tears that magnetize enemies they hit, causing them to attract nearby pickups and enemies, as well as tears/shots from all sources. | 3 |
![]() |
5.100.612 | ![]() |
Protect him | Gives Isaac a soul familiar that dies in one hit, respawning at the start of the next floor. If it survives an entire floor, it rewards Isaac with hearts or items. | 2 |
![]() |
5.100.589 | ![]() |
The moon's blessing shines upon you | Adds an extra Secret Room and Super Secret Room to each floor. Secret Rooms contain a beam of light that increases tears for the current floor and give soul hearts. | 2 |
![]() |
5.100.593 | ![]() |
Double tap dash | Dash by double-tapping the movement key, becoming invulnerable and damaging enemies. There's a short cooldown before Isaac can dash again. | 2 |
![]() |
5.100.602 | ![]() |
Exclusive access! | Adds a trapdoor to every shop that leads to a second shop with a unique stock and marked up prices. | 1 |
![]() |
5.100.590 | ![]() |
Speed up + you feel elusive | +0.4 speed. Doors stay open after entering a room, even in rooms with enemies. | 3 |
![]() |
5.100.574 | ![]() |
Purifying light | Isaac gains an aura that deals damage to enemies inside it. | 2 |
![]() |
5.100.680 | ![]() |
Oh no... | While firing, Isaac charges up a short-ranged ![]() |
3 |
![]() |
5.100.553 | ![]() |
Spore shot | Gives Isaac the chance to fire spore tears that stick to enemies and blow up after a few seconds, dealing damage and poisoning nearby enemies and releasing more spores. | 3 |
![]() |
5.100.563 | ![]() |
Random blast +5 bombs | +5 bombs. Bombs explode with a random bomb effect. | 1 |
![]() |
5.100.597 | ![]() |
Open the floodgates | Isaac's mouth fills with tears over time while not firing, up to a cap. Holding the fire button will release all stored tears in rapid succession. | 3 |
![]() |
5.100.606 | ![]() |
Stare into the abyss | Gives Isaac the chance to fire tears that create rifts where they land, which damage nearby enemies and pull in enemies, pickups, and tears/shots from all sources. | 3 |
![]() |
5.100.670 | ![]() |
There might be options | If a room gives a reward when cleared, there will be two different rewards to chose from. Taking one causes the other to disappear. | 2 |
![]() |
5.100.571 | ![]() |
Speed up + your feet feel stronger | Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 soul hearts. | 1 |
![]() |
5.100.567 | ![]() |
Keep the flame burning | Gives Isaac a tears bonus based on how many consecutive rooms he's cleared without taking damage. | 3 |
![]() |
5.100.570 | ![]() |
Tasty rainbow | Grants multicolored tears. Each color comes with a different status or tear effect. | 3 |
![]() |
5.100.598 | ![]() |
Size down | Significantly shrinks Isaac, allowing him to squeeze between objects and makes some enemy shots pass over him. Also gives +0.7 tears. | 3 |
![]() |
5.100.581 | ![]() |
Flamboyant protector | Spawns a fly orbital familiar that chases and deflects enemy shots and converts them into homing tears. | 3 |
![]() |
5.100.634 | ![]() |
Help from beyond | While in a room with enemies, spawns cracks on the ground. Walking over these cracks summons ghosts that launch themselves at enemies and explode. | 2 |
![]() |
5.100.661 | ![]() |
They lurk inside | Killing enemies spawns a stationary shooting familiar where they died for the current room. | 1 |
![]() |
5.100.621 | ![]() |
Full HP + temporary DMG up | Refills all heart containers. Grants an enormous damage boost that wears off over time. | 0 |
![]() |
5.100.673 | ![]() |
Deliver me from evil | Gives Isaac a soul heart and +1 damage if he goes into a Devil Room but doesn't take anything from it. | 2 |
![]() |
5.100.643 | ![]() |
Awaken your faith | Allows Isaac to charge a holy laser by continuously firing for 2.5 seconds, then releasing the fire buttons. Also gives Isaac flight and 2 soul hearts. | 4 |
![]() |
5.100.562 | ![]() |
It's only up from there | Locks Isaac's attributes to their highest values reached. | 2 |
![]() |
5.100.583 | ![]() |
Rocket propulsion +5 bombs | +5 bombs. If Isaac is currently moving, placing a bomb will instead shoot a fast-moving, explosive rocket in the direction he's facing. | 2 |
![]() |
5.100.618 | ![]() |
Delicious! | Adds a chance to fire tears that Mark enemies. Marked enemies are attacked by other enemies. | 1 |
![]() |
5.100.691 | ![]() |
Destined for greatness | Prevents low-quality items from spawning, greatly increasing the quality of items received from all items pools. | 4 |
![]() |
5.100.696 | ![]() |
Divine protection | Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor. | 2 |
![]() |
5.100.692 | ![]() |
He awaits your offering | Spawns a special set of spikes in the Devil Room. Taking damage from the spikes has a chance to grant a reward. | 1 |
![]() |
5.100.595 | ![]() |
Ring of tears | Upon entering a room, a circle of tears orbits Isaac. Enemy tears have a chance to be caught in orbit, turning them friendly. | 1 |
![]() |
5.100.669 | ![]() |
All stats up | Adds a Red Heart container, and increases speed, damage, tears, range, shot speed, and luck. | 3 |
![]() |
5.100.588 | ![]() |
Radiant victory | Reveals the location of the Boss room. Upon defeating a boss, activates XIX - The Sun, fully recharges Isaac's active item, and grants bonus damage and luck for the rest of the floor. | 2 |
![]() |
5.100.686 | ![]() |
Power of faith | Gives Isaac a permanent stat boost whenever he picks up a soul heart. | 2 |
![]() |
5.100.674 | ![]() |
Unfinished business | On death, Isaac's ghost is chained to his dead body and he can continue to fight with 1/2 of a heart, returning to life after 10 seconds. Must be recharged by picking up a soul heart. | 3 |
![]() |
5.100.579 | ![]() |
Divine blade | Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is sometimes fired with normal swings if Isaac has no empty red hearts. | 3 |
![]() |
5.100.708 | ![]() |
DMG up | +1 damage. Prevents Isaac from firing tears from one eye, like Cain. | 3 |
![]() |
5.100.651 | ![]() |
Follow the light | Spawns a star familiar that slowly travels towards the Boss Room, giving an aura that increases damage and tears and grants homing. | 2 |
![]() |
5.100.667 | ![]() |
A helping hand | Spawns Keeper to fight enemies alongside Isaac. If Keeper dies, he spawns blue spiders and Strawman is removed from Isaac's inventory. | 2 |
![]() |
5.100.707 | ![]() |
HP up | Grants one Red Heart container and heals for one extra heart. | 1 |
![]() |
5.100.592 | ![]() |
Born to rock | Replaces tears with rocks that deal variable damage, have increased knockback, and can destroy obstacles. | 3 |
![]() |
5.100.575 | ![]() |
Invasive friend | A familiar burrows in Isaac's head, firing 4 slowing tears. Upon taking damage, there's a chance it will burst out of Isaac's head, spawning blue spiders and chasing enemies for the current room. | 3 |
![]() |
5.100.586 | ![]() |
May you get what you came for | Generates a ladder at the start of every floor that leads to a unique Angel Room shop. | 3 |
![]() |
5.100.693 | ![]() |
Infest | Spawns nine orbital flies, which turn into Blue Flies after they block a shot. Each time a room is cleared, spawns another orbital fly. | 2 |
![]() |
5.100.645 | ![]() |
Itching for revenge | Gives Isaac a Teratoma orbital that blocks shots, deals contact damage, and splits into smaller versions of itself upon taking damage. The smaller versions break into blue spiders. | 1 |
![]() |
5.100.721 | ![]() |
ZZaZZ ZZdZZiZZmZZhZZ ZZvZZ ZZoZZ ZZ ZZsZZlZZhZZsZZoZZaZZiZZ | Causes all future items to be "glitched", granting them completely random effects. | 2 |
![]() |
5.100.663 | ![]() |
You feel prickly | Isaac periodically turns into a spiked statue, briefly becoming invulnerable and dealing contact damage. | 2 |
![]() |
5.100.659 | ![]() |
Tear size + range up | +1.5 range, Increases tear size. | 1 |
![]() |
5.100.698 | ![]() |
Double trouble! | Gives Isaac two familiars that stand by Isaac's side and fire tears that use Isaac's tears, range, shot speed, and tear effects and scale with Isaac's damage. | 4 |
![]() |
5.100.596 | ![]() |
Ice tears | Isaac shoots ice tears, which slow enemies and freeze monsters they kill. Frozen enemies slide away and explode into ice shards when touched. | 3 |
![]() |
5.100.697 | ![]() |
He wants revenge | Spawns a familiar that becomes a clone of the floor's boss when entering the boss room. Defeating it drops an extra item. | 3 |
![]() |
5.100.657 | ![]() |
Clogged enemies | Enemies explode into tears upon death, which inherit the effects of Isaac's tears. | 2 |
![]() |
5.100.702 | ![]() |
Hot blooded | After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots. | 2 |
![]() |
5.100.591 | ![]() |
HP up + you feel pretty | Adds one red Heart container. Enemies near Isaac become charmed. | 1 |
![]() |
5.100.599 | ![]() |
Extra curse rooms | Spawns an additional curse room on each floor. | 1 |
![]() |
5.100.682 | ![]() |
Clingy buddy | Gives Isaac a nerve ending familiar that burrows out of the ground to grab and deal damage to enemies over time. | 2 |
![]() |
5.100.474 | ![]() |
Gross... | Grants a familiar that can block enemy shots. |
Trivia
Wiggle Worm was an item in the original The Binding of Isaac; however, in Rebirth, it was changed into a trinket.
The Polaroid was a trinket in the original The Binding of Isaac, but it was changed into an item. Interestingly, these changes keep the count of items and trinkets from the original game the same.
- There are a total of 123 active items, with 74 in Rebirth, 19 in Afterbirth, and 30 in Afterbirth+. Of those, 101 items utilize a charge bar, with 61 items in Rebirth, 16 in Afterbirth, and 24 in Afterbirth+.
- There are a total of 424 passive items, with 267 in Rebirth, 76 in Afterbirth, and 81 in Afterbirth+.
- From Rebirth to Afterbirth+, there has been about a 1:4 ratio of active items to passive items.
Afterbirth+'s original item count was 89. The Booster Packs added 42 items.
![]() ![]() | |||||
---|---|---|---|---|---|
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |