Binding of Isaac: Rebirth Wiki
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(in Repentance)

Items with this tag are familiars which are unique and cannot be duplicated by Collectible Box of Friends iconBox of Friends, and Soul of LilithSoul of Lilith can grant them only once. Note that this does not prevent getting multiple copies of the items through duplication effects such as Collectible Diplopia iconDiplopia.


Activated Collectibles[ | ]

Name ID Icon Quote Description Quality
Stitches 5.100.635
Stitches
3 seconds
Bait and switch Passively spawns a familiar that moves in the direction Isaac shoots. On use, Isaac swaps places with the familiar. 1

Passive Collectibles[ | ]

Name ID Icon Quote Description Quality
Dead Cat 5.100.81 Dead Cat 9 lives Sets Isaac's Red Heart Containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container. 3
Isaac's Heart 5.100.276 Isaac's Heart Protect it Isaac himself is now immune to all damage, and a heart familiar follows him. If the heart is hurt, Isaac is hurt. (in Repentance) The heart charges up as Isaac shoots, firing 8 blood shots, knocking back enemies, and leaving a puddle of creep when released. 0
Key Piece 1 5.100.238 Key Piece 1 ??? Combined with Collectible Key Piece 2 iconKey Piece 2, unlocks the golden gate in the starting room of ChestChest and Dark RoomDark Room to fight Mega Satan Head ingameMega Satan. 0
Key Piece 2 5.100.239 Key Piece 2 ??? Combined with Collectible Key Piece 1 iconKey Piece 1, unlocks the golden gate in the starting room of ChestChest and Dark RoomDark Room to fight Mega Satan Head ingameMega Satan. 0
Milk! 5.100.436 Milk! Don't cry over it... Spawns a glass familiar that spills on the floor upon taking damage. (except in Repentance) After the milk spills, Isaac's tear delay is decreased by 2 for the current room. (in Repentance) After the milk spills, Isaac's fire rate is increased by 1 for the current room. 1
Blood Oath 5.100.569 Blood Oath Bleed me dry Stabs Isaac at the beginning of each floor, draining his Red HeartRed Hearts. Increases damage and speed for the floor based on the amount drained. 1
Knife Piece 1 5.100.626 Knife Piece 1 ??? Combined with Collectible Knife Piece 2 iconKnife Piece 2, creates a knife familiar that damages enemies and can open the door to the CorpseCorpse. 0
Knife Piece 2 5.100.627 Knife Piece 2 ??? Combined with Collectible Knife Piece 1 iconKnife Piece 1, creates a knife familiar that damages enemies and can open the door to the CorpseCorpse. 0
Paschal Candle 5.100.567 Paschal Candle Keep the flame burning Gives Isaac a familiar that grants +0.4 Fire Rate for each consecutive room he's cleared without taking damage. The bonus stacks up to five times. 3
Vanishing Twin 5.100.697 Vanishing Twin He wants revenge Spawns a familiar that becomes a clone of the floor's boss when entering the Boss RoomBoss Room. Defeating it drops an extra item. 2


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