Binding of Isaac: Rebirth Wiki
(in Repentance)

Items with this tag contribute toward the Spun transformation and the unlock of Little Baggy Little Baggy.

Passive Collectibles[ | ]

Name ID Icon Quote Description Quality
Experimental Treatment 5.100.240 Experimental Treatment Some stats up, some stats down (in Rebirth and Afterbirth) Randomly increases and decreases some of Isaac's stats.
(in Afterbirth † and Repentance) Increases four random stats and decreases the other two.
Growth Hormones 5.100.70 Growth Hormones Speed + DMG up (except in Repentance) +1 damage, +0.4 speed.
(in Repentance) +1 damage, +0.2 speed.
Roid Rage 5.100.14 Roid Rage Speed and range up (except in Repentance) +0.6 speed, +5.25 range, +0.5 tear falling speed.
(in Repentance) +0.3 speed, +2.5 range
Speed Ball 5.100.143 Speed Ball Speed + shot speed up +0.3 speed, +0.2 shot speed. 2
Synthoil 5.100.345 Synthoil DMG + range up (except in Repentance) +1 damage, +5.25 range, +0.5 tear falling speed.
(in Repentance) +1 damage, +2.5 range.
The Virus 5.100.13 The Virus Poison touch + speed up Isaac poisons enemies on contact. (except in Repentance) -0.1 speed. (in Repentance) +0.2 speed. (in Afterbirth and Afterbirth †) Poisoned enemies have a chance to drop a black heart when killed. 2
Adrenaline 5.100.493 Adrenaline Panic = power Increases damage based on how many empty Red Heart containers Isaac has. 2
Euthanasia 5.100.496 Euthanasia Needle shot Adds a chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles. 3