Items with this tag contribute toward the Spider Baby transformation.
Activated Collectibles[ | ]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Box of Spiders | 5.100.288 |  
|
It's a box of spiders |  Spawns 1-4 Blue Spiders that deal 2.5x Isaac's damage to enemies. Spawns 4-8 Blue Spiders that deal 2x Isaac's damage to enemies.
|
1 |
| Spider Butt | 5.100.171 | 
|
Mass enemy slowdown + damage | Deals 10 damage to all enemies in the room and slows them for 4 seconds. Enemies killed by Spider Butt spawn Blue Spiders.
|
1 |
Passive Collectibles[ | ]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Daddy Longlegs | 5.100.170 | 
|
Daddy's love | Daddy Long Legs' shadow follows Isaac and occasionally stomps enemies for 40 damage total. | 3 |
| Hive Mind | 5.100.248 | 
|
Giant spiders and flies | Increases the size of Blue Spiders and Blue Flies and doubles the amount of damage they deal. Also increases the effectiveness of fly and spider familiars.
|
2 |
| Infestation 2 | 5.100.234 | 
|
Infestation shot | Spawns allied Blue Spiders from killed enemies. | 3 |
| Juicy Sack | 5.100.266 | 
|
Sticky babies | Spawns a familiar that follows Isaac and drips a trail of slow creep, spawning 1-2 Blue Spiders after each room. | 2 |
| Mutant Spider | 5.100.153 | 
|
Quad shot | Grants quadruple shot but decreases Tears. | 3 |
| Sissy Longlegs | 5.100.280 | 
|
She loves you | Spawns a familiar that wanders randomly, occasionally spawning Blue Spiders. Briefly charms enemies on contact.
|
1 |
| Spider Bite | 5.100.89 | 
|
Slow effect | Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them. | 2 |
| Spiderbaby | 5.100.211 | 
|
Spider revenge | Spawns 1-2 Blue Spiders when Isaac takes damage. Spawns 3-5 Blue Spiders when Isaac takes damage.
|
0 |
| Bursting Sack | 5.100.377 | 
|
Spider love | Spider enemies no longer target or deal contact damage to Isaac. | 1 |
| Spider Mod | 5.100.403 | 
|
Mod buddy! | Displays Isaac's tear damage and enemy health bars. Spawns a familiar that wanders around and inflicts random status effects on enemies it touches. Can spawn a  Lil' Battery/Blue spider upon clearing a room.
|
1 |
| Sticky Bombs | 5.100.367 | 
|
Egg sack bombs! | +5  Bombs. Bombs stick to enemies and spawn 2-4 Blue Spiders if they kill an enemy. They also leave a long-lasting puddle of slowing white creep.
|
2 |
| Parasitoid | 5.100.461 | 
|
Egg tears! | Adds a chance to fire an egg sack which creates slowing creep and spawns a Blue Fly or Blue Spider upon hitting an enemy. | 3 |
| Keeper's Kin | 5.100.717 | 
|
Under a rock | Rocks and other Obstacles spawn blue spiders over time while in a room with enemies, and spawn two blue spiders when destroyed. | 2 |
| The Intruder | 5.100.575 | 
|
Invasive friend | A familiar burrows in Isaac's head, firing 4 slowing tears. Upon taking damage, there's a chance it will burst out of Isaac's head, spawning blue spiders and chasing enemies for the current room. | 3 |
 The Binding of Isaac: Rebirth
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