Binding of Isaac: Rebirth Wiki
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(in Repentance)


Items with this tag are not available to Character The Lost iconThe Lost after obtaining Collectible Birthright iconBirthright. Most of these are health-related or related to "on hit" effects, since The Lost has no health. Some of these are also related to abilities The Lost already has, such as spectral tears or flight.

Activated Collectibles[ | ]

Name ID Icon Quote Description Quality
Blood Rights 5.100.186
Blood Rights
Unlimited
Mass enemy damage at a cost Upon use, takes a full heart of health and deals 40 damage to all enemies in the room. (in Repentance) Repeated uses in the same room only take half a heart. 0
Book of Revelations 5.100.78
Book of Revelations
6 rooms
Reusable soul protection Increases the chance of a Devil RoomDevil Room / Angel RoomAngel Room appearing while held. On use, gives one Soul HeartSoul Heart, and replaces the boss of the current floor with a Harbinger if possible. 3
Breath of Life 5.100.326
Breath of Life
3 seconds
Invincibility at a cost Grants a brief moment of invincibility when the charge bar hits zero. Isaac begins taking damage if the item is held any longer. (in Repentance) Isaac creates beams of light when touching enemies while invulnerable, and creates a powerful 4-way beam if blocking damage exactly as the invincibility starts. 1
Converter 5.100.296
Converter
3 rooms
Convert your soul (except in Repentance) Converts two Soul HeartSoul Hearts or Black HeartBlack Hearts into one filled Red HeartRed Heart Container.
(in Repentance) Converts one Soul HeartSoul Heart or Black HeartBlack Heart into one filled Red HeartRed Heart Container.
2
Guppy's Paw 5.100.133
Guppy's Paw
Unlimited
Soul converter Upon use, converts one Red Heart Container into three Soul HeartSoul Hearts. 3
IV Bag 5.100.135
IV Bag
Unlimited
Portable blood bank Upon use, Isaac loses half a heart of health (or a full heart in Chapter 4 onward) for a random amount of coins, similar to a Blood Donation MachineBlood Donation Machine. 1
Kamikaze! 5.100.40
Kamikaze!
Unlimited
Become the bomb! Creates an explosion around Isaac, damaging him and nearby enemies as well as destroying obstacles. 0
Prayer Card 5.100.146
Prayer Card
6 rooms
Reusable eternity Gives an Eternal HeartEternal Heart per use. 3
Razor Blade 5.100.126
Razor Blade
Unlimited
Feel my pain Takes one Red HeartHeart of health and grants +1.2 damage for the current room. (in Repentance) Repeated uses in the same room only take half a heart. 0
Satanic Bible 5.100.292
Satanic Bible
6 rooms
Reusable evil... but at what cost? Gives one Black HeartBlack Heart. (in Repentance) Replaces the boss room item on the current floor with a Devil Deal. 4
The Jar 5.100.290
The Jar
Unlimited
Save your life When at full health, up to 4 extra Red HeartRed Hearts can be stored in The Jar. Activating drops the stored hearts on the ground. 0
Yum Heart 5.100.45
Yum Heart
4 rooms
Reusable regeneration Restores one full Red HeartRed Heart. 1
Clicker 5.100.482
Clicker
6 rooms
Change Transforms Isaac into a random character and removes the last item collected. 0
Potato Peeler 5.100.487
Potato Peeler
Unlimited
A pound of flesh Removes a Heart Container, increases damage and range, and grants a Collectible Cube of Meat iconCube of Meat. 2
Sumptorium 5.100.713
Sumptorium
10 seconds
Blood to blood Removes half a heart and creates a Clot familiar that mimics Isaac's movements and tear effects. As Character Tainted Eve iconTainted Eve, passively converts health into Clots while firing. Activating returns all Clots to health. 3
Yuck Heart 5.100.639
Yuck Heart
4 rooms
Gross! Gives Isaac a Rotten HeartRotten Heart. 1

Passive Collectibles[ | ]

Name ID Icon Quote Description Quality
<3 5.100.15 <3 HP up Grants Isaac one Red Heart container and fully restores Isaac's health. 2
A Snack 5.100.346 A Snack HP up Grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 1
Anemic 5.100.214 Anemic Toxic blood After Isaac is damaged, a trail of red creep will be left behind him until he leaves the current room. (except in Repentance) +5 range. (in Repentance) +1.5 range. 1
Ankh 5.100.161 Ankh Eternal life? Upon death, Isaac will respawn as Character ??? (Character) icon??? in the previous room, with 3 Soul HeartSoul Hearts. 1
Best Bud 5.100.274 Best Bud Sworn protector When hit, spawns a quickly orbiting attack fly similar to Collectible Forever Alone iconForever Alone for the current room that deals high damage. 0
Black Lotus 5.100.226 Black Lotus HP up x3! Grants one Red Heart Container, one Soul HeartSoul Heart, and one Black HeartBlack Heart. 2
Blood Bag 5.100.119 Blood Bag HP up Grants one filled Red Heart container, restores 4 Red HeartRed Hearts, and increases speed by 0.3. 2
Bloody Lust 5.100.157 Bloody Lust RAGE! Increases Isaac's damage whenever he takes damage, up to six times. The bonus resets when entering a new floor. 2
Breakfast 5.100.25 Breakfast HP up Grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 1
Bucket of Lard 5.100.129 Bucket of Lard HP up (except in Repentance) Grants two empty Red Heart containers, heals Isaac for a Half Red HeartHalf Red Heart, -0.2 speed.
(in Repentance) Grants two Red Heart containers, -0.2 speed.
1
Cancer 5.100.301 Cancer HP up + you feel protected Adds 3 Soul HeartSoul Hearts. Grants Collectible The Wafer iconThe Wafer effect for the current room after taking damage. 3
Celtic Cross 5.100.162 Celtic Cross Blessing of protection Grants a chance to trigger the Collectible Book of Shadows iconBook of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds. 1
Charm of the Vampire 5.100.62 Charm of the Vampire DMG up + kills heal Heals Isaac for a Half Red HeartHalf Red Heart for every 13 enemies killed. (in Repentance) +0.3 damage. 1
Dead Bird 5.100.117 Dead Bird Protective buddy After Isaac takes damage, spawns a flying familiar that chases enemies for the current room, dealing ~4 damage per second. 0
Dead Dove 5.100.185 Dead Dove Flight + spectral tears Grants spectral tears and flight. 3
Dessert 5.100.24 Dessert HP up Grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 1
Dinner 5.100.23 Dinner HP up Grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 1
E. Coli 5.100.236 E Turdy touch Enemies that touch Isaac are transformed into PoopPoop. 1
Fanny Pack 5.100.204 Fanny Pack Filled with goodies Has a chance to drop a random pickup when Isaac takes damage. 1
Fate 5.100.179 Fate Flight eternal Grants flight and one Eternal HeartEternal Heart. 3
Gimpy 5.100.225 Gimpy Sweet suffering Gives chance of spawning a Soul HeartSoul Heart when taking damage. Enemies have a chance to drop a Half Red HeartHalf Red Heart after being killed. 2
Habit 5.100.156 Habit Item martyr When Isaac is hit, his active item gains 1 room's worth of charge. 2
Holy Grail 5.100.184 Holy Grail Flight + HP up Grants flight and one Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 3
Infestation 5.100.148 Infestation Fly revenge (except in Repentance) 1-3 Blue Flies randomly spawn every time Isaac gets hit.
(in Repentance) 2-6 Blue Flies
0
Isaac's Heart 5.100.276 Isaac's Heart Protect it Isaac himself is now immune to all damage, and a heart familiar follows him. If the heart is hurt, Isaac is hurt. (in Repentance) The heart charges up as Isaac shoots, firing 8 blood shots, knocking back enemies, and leaving a puddle of creep when released. 0
Judas' Shadow 5.100.311 Judas' Shadow Sweet revenge Upon death, respawns Isaac as Character Dark Judas iconDark Judas with two Black HeartBlack Hearts in the previous room. 3
Lazarus' Rags 5.100.332 Lazarus' Rags Eternal life? (except in Repentance) Upon dying, resurrect as Character Lazarus Risen iconLazarus Risen in the current room with one Red Heart container and Collectible Anemic iconAnemic.
(in Repentance) Upon dying, resurrect as Character Lazarus Risen iconLazarus Risen in the current room with one less Red Heart container, Collectible Anemic iconAnemic, and +0.5 Damage. Transform into Character Lazarus iconLazarus when reaching the next floor.
1
Little C.H.A.D. 5.100.96 Little C.H.A.D. Gives kisses Spawns a familiar who drops a Half Red HeartHalf Red Heart every 3 rooms. 2
Lord of the Pit 5.100.82 Lord of the Pit Demon wings Grants flight and +0.3 speed. 3
Lunch 5.100.22 Lunch HP up Grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 1
Maggy's Bow 5.100.312 Maggy's Bow HP up + you feel healthy Gives one Red Heart Container and doubles the healing provided by Red HeartRed Hearts. (in Repentance) Also heals 1 Red Heart when obtained. 2
Magic Scab 5.100.253 Magic Scab HP + luck up Grants one full Red Heart container, +1 luck. (in Repentance) Heals 1 additional Red HeartRed Heart. 2
MEAT! 5.100.193 MEAT! DMG + HP up Grants one full Red Heart container, +0.3 damage. (in Repentance) Heals 1 additional Red HeartRed Heart 2
Midas' Touch 5.100.202 Midas' Touch Golden touch Enemies that touch Isaac are temporarily petrified and turn to gold. Any enemy killed while in this state will drop PennyPennies. 2
Missing Page 2 5.100.262 Missing Page 2 Evil up. Your enemies will pay! Grants one Black HeartBlack Heart. Upon taking damage that reduces Isaac's health to one heart or less, deals damage to all enemies in the room. (in Repentance) Increases the damage of Black HeartBlack Hearts and Collectible The Necronomicon iconThe Necronomicon-like effects by 40. 0
Old Bandage 5.100.219 Old Bandage HP up Grants an empty Red Heart container. Adds a chance of dropping a Red HeartRed Heart after taking damage. 2
Ouija Board 5.100.115 Ouija Board Spectral tears + tears up Grants spectral tears that travel through obstacles (but not enemies). (in Repentance) +0.5 tears. 2
Piggy Bank 5.100.227 Piggy Bank My life savings Gives 3 PennyPennies on pick-up. Every time Isaac is damaged, he will drop one or two additional pennies. 1
Placenta 5.100.218 Placenta Regeneration + HP up Grants one full Red Heart container, and a chance to regenerate a Half Red HeartHalf Red Heart of health every minute of gameplay. 2
Raw Liver 5.100.16 Raw Liver HP up Grants 2 Red Heart containers and completely restores health. 2
Rosary 5.100.72 Rosary Tears + faith up Grants 3 Soul HeartSoul Hearts. Causes Collectible The Bible iconThe Bible to appear in any item pool. (in Repentance) +0.5 tears. 2
Rotten Meat 5.100.26 Rotten Meat HP up Grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 1
Scapular 5.100.142 Scapular Pray for a miracle Once per room, when Isaac is reduced to his last half heart, he is granted one Soul HeartSoul Heart. 2
Sharp Plug 5.100.205 Sharp Plug Infinite charge... at a cost Damages Isaac in exchange for fully recharging Isaac's current activated item. 2
Spiderbaby 5.100.211 Spiderbaby Spider revenge (except in Repentance) Spawns 1-2 Blue Spiders when Isaac takes damage.
(in Repentance) Spawns 3-5 Blue Spiders when Isaac takes damage.
0
Spirit of the Night 5.100.159 Spirit of the Night Scary Grants spectral tears and flight. 3
Stem Cells 5.100.176 Stem Cells HP + shot speed up Grants one full Red Heart container and +0.16 shot speed. (in Repentance) Heals 1 additional Red HeartRed Heart 1
Super Bandage 5.100.92 Super Bandage +2 hearts Grants one full Red Heart container and 2 Soul HeartSoul Hearts. 2
The Black Bean 5.100.180 The Black Bean Toot on touch (except in Repentance) When taking damage, Isaac farts, poisoning enemies in range.
(in Repentance) When taking damage, Isaac farts five times, poisoning and knocking back nearby enemies and leaving lingering poison clouds.
0
The Body 5.100.334 The Body I feel all Adds 3 Red Heart Containers. 3
The Ladder 5.100.60 The Ladder Building bridges Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections. 1
The Relic 5.100.98 The Relic Soul generator Spawns a cross familiar that drops a Soul HeartSoul Heart after clearing enough rooms. 3
The Virus 5.100.13 The Virus Poison touch + speed up Isaac poisons enemies on contact. (except in Repentance) -0.1 speed. (in Repentance) +0.2 speed. (in Afterbirth and Afterbirth †) Poisoned enemies have a chance to drop a black heart when killed. 2
The Wafer 5.100.108 The Wafer Damage resistance Most sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead. 4
Thunder Thighs 5.100.314 Thunder Thighs HP up + speed down + you feel stompy Destroys rocks upon contact with Isaac. Adds one Red Heart container and lowers Speed. 1
Transcendence 5.100.20 Transcendence We all float down here... Grants flight. 3
Cambion Conception 5.100.412 Cambion Conception Feed them hate After taking damage a certain amount of times, a permanent demonic familiar spawns. 2
Crack Jacks 5.100.354 Crack Jacks HP up. Don't swallow the prize! Grants one full Red Heart container and drops a random trinket. (in Repentance) Heals 1 additional Red HeartRed Heart. 2
Curse of the Tower 5.100.371 Curse of the Tower Embrace chaos Upon taking damage, spawns six Troll BombTroll Bombs around the room, similar to the effect of XVI - The TowerXVI - The Tower. 0
Immaculate Conception 5.100.413 Immaculate Conception Feed them love Upon picking up a certain amount of health, spawn a permanent angelic familiar. 1
Milk! 5.100.436 Milk! Don't cry over it... Spawns a glass familiar that spills on the floor upon taking damage. (except in Repentance) After the milk spills, Isaac's tear delay is decreased by 2 for the current room. (in Repentance) After the milk spills, Isaac's fire rate is increased by 1 for the current room. 1
PJs 5.100.428 PJs You feel cozy Grants 4 Soul HeartSoul Hearts and fully restores Isaac's health. 2
Adrenaline 5.100.493 Adrenaline Panic = power Increases damage based on how many empty Red Heart containers Isaac has. 2
Bozo 5.100.513 Bozo Party time! +0.1 flat damage, grants a Soul HeartSoul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a Rainbow PoopRainbow Poop. 2
Brittle Bones 5.100.549 Brittle Bones Everything hurts Replaces all Red HeartRed Heart Containers with 6 empty Bone HeartBone Hearts. (except in Repentance) Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a tears up. (in Repentance) Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a fire rate up. 3
Dark Prince's Crown 5.100.442 Dark Prince's Crown Loss is power (except in Repentance) When at exactly one Red HeartRed Heart, +0.75 tears, +1.5 range, and +0.2 shot speed.
(in Repentance) When at exactly one Red HeartRed Heart, +2 fire rate, +1.5 range, and +0.2 shot speed.
1
Greed's Gullet 5.100.501 Greed's Gullet Money = health! Grants a Red Heart container for every 25 PennyCoins Isaac has. 1
Hallowed Ground 5.100.543 Hallowed Ground Portable sanctuary Spawns a white poop familiar, which turns into a White PoopWhite Poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. (in Repentance) The aura also increases damage by 20% and gives homing. 1
Leprosy 5.100.525 Leprosy You're tearing me apart! Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots. 1
Marrow 5.100.541 Marrow HP up? Grants one Bone HeartBone Heart and spawns three Red HeartRed Hearts. 1
Midnight Snack 5.100.456 Midnight Snack HP up Grants one full Red Heart container. (in Repentance) Heals 1 additional Red HeartRed Heart. 1
Mystery Egg 5.100.539 Mystery Egg Sacrificial insemination Spawns an egg familiar, which hatches a random friendly monster when Isaac is hurt once per room. The power of the monster improves for each consecutive room cleared without taking damage. 1
Shard of Glass 5.100.448 Shard of Glass Blood and guts! (except in Repentance) Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room.
(in Repentance) Taking damage causes Isaac to bleed, spraying a volley of blood in the direction he fires. Bleeding will eventually damage him, but it can be stopped by picking up a Red HeartRed Heart.
1
Varicose Veins 5.100.452 Varicose Veins I'm leaking... Taking damage releases a ring of 10 high damage tears. 1
Astral Projection 5.100.677 Astral Projection The true out-of-body experience! Causes Isaac to turn into a ghost if he gets hit while in an uncleared room, giving him flight and spectral tears and blocking the next hit he takes. 2
Binge Eater 5.100.664 Binge Eater All you can eat +1 Red Heart Container and fully heals Isaac. Item pedestals also offer a random food item. Picking up a food item temporarily grants +3.6 damage and permanently boosts 2 stats. 4
Bird Cage 5.100.610 Bird Cage Fat buddy The first time Isaac takes damage in a room, a familiar leaps on an enemy, dealing damage and releasing a rock wave. For the rest of the room, it chases enemies similar to Collectible Dead Bird iconDead Bird. 1
Blood Bombs 5.100.614 Blood Bombs Bloody blast + HP up Grants a Red Heart container and restores 5 hearts. Bombs leave behind damaging red creep. Isaac can place BombBombs at the cost of half a heart if he doesn't have any. 2
Blood Oath 5.100.569 Blood Oath Bleed me dry Stabs Isaac at the beginning of each floor, draining his Red HeartRed Hearts. Increases damage and speed for the floor based on the amount drained. 1
Bloody Gust 5.100.695 Bloody Gust May your rage bring haste The first 6 times Isaac takes damage on a given floor, he gains Speed and Fire Rate for the rest of the floor, up to a maximum of +1.02 and +3.00, respectively. 2
Candy Heart 5.100.671 Candy Heart Power of love Gives Isaac a permanent stat boost whenever he heals with Red HeartRed Heart pickups. 1
Cracked Orb 5.100.675 Cracked Orb Shards of knowledge Unlocks doors and reveals a random room on the map when Isaac takes damage. 1
Empty Heart 5.100.676 Empty Heart It multiplies If Isaac has one red heart or fewer at the beginning of a floor, he gains an empty red heart container. 1
Giant Cell 5.100.658 Giant Cell Micro friends Causes Isaac to spawn Minisaac familiars when he takes damage, which chase and shoot at nearby enemies. 1
Hypercoagulation 5.100.724 Hypercoagulation Thick blooded After Isaac takes damage from an enemy or donates health, launches Red HeartRed Hearts from Isaac that despawn after 1.5 seconds. 2
It Hurts 5.100.560 It Hurts No it doesn't... Releases a ring of tears and increases fire rate for the current room when Isaac takes damage. 1
Orphan Socks 5.100.571 Orphan Socks Speed up + your feet feel stronger Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 Soul HeartSoul Hearts. 2
Sanguine Bond 5.100.692 Sanguine Bond He awaits your offering Spawns a special set of spikes in the Devil RoomDevil Room. Taking damage from the spikes has a chance to grant a reward. 1
Supper 5.100.707 Supper HP up Grants one full Red Heart container. Heals 1 additional Red HeartRed Heart. 1
Vengeful Spirit 5.100.702 Vengeful Spirit Hot blooded After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots. 1


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