Binding of Isaac: Rebirth Wiki
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Binding of Isaac: Rebirth Wiki
Added in Repentance

Items in this pool will not spawn if The Lost The Lost has the item 15►Birthright Birthright. It generally includes items that are useless to The Lost, ones that only grant health, flight, spectral tears or activate upon taking damage. It is similar, but not identical, to the item logic used by Tainted Lost Tainted Lost.

Activated Collectibles[]

Name ID Icon Quote Description Quality
Blood Rights 5.100.186
Blood Rights
Unlimited
Mass enemy damage at a cost Upon use, takes a full heart of health and deals 40 damage to all enemies in the room. 0
Book of Revelations 5.100.78
Book of Revelations
6 rooms
Reusable soul protection Gives one Soul Heart, increases the chance for a Devil or Angel Room, and changes the boss of the current floor to a Harbinger if possible. 3
Breath of Life 5.100.326
Breath of Life
6 seconds
Invincibility at a cost Grants a brief moment of invincibility when the charge bar hits zero. If the spacebar is held for an additional second after hitting zero, Isaac will take damage. 0
Converter 5.100.296
Converter
Unlimited
Convert your soul Removed in Repentance Converts two Soul Hearts into one full Heart Container.
Added in Repentance Converts one Soul or Black Heart into one full Heart Container.
1
Guppy's Paw 5.100.133
Guppy's Paw
Unlimited
Soul converter Upon use, converts one Heart Container into three Soul Hearts. 3
IV Bag 5.100.135
IV Bag
Unlimited
Portable blood bank Upon use, Isaac loses half a heart of health (one in Womb Womb onward) for a random amount of coins, similar to a Blood Donation Machine. 1
Kamikaze! 5.100.40
Kamikaze!
Unlimited
Become the bomb! Creates an explosion around Isaac, damaging him and nearby enemies as well as destroying obstacles. 0
Prayer Card 5.100.146
Prayer Card
6 rooms
Reusable eternity Gives an Eternal Heart per use. 3
Razor Blade 5.100.126
Razor Blade
Unlimited
Feel my pain On use, takes one heart of health and grants +1.2 damage for the current room. 0
Satanic Bible 5.100.292
Satanic Bible
6 rooms
Reusable evil... but at what cost? Gives one Black Heart. Added in Repentance Replaces the boss room item on the current floor with a Devil deal. 4
The Jar 5.100.290
The Jar
Unlimited
Save your life When at full health, up to 4 extra Red Hearts can be stored in The Jar. 0
Yum Heart 5.100.45
Yum Heart
4 rooms
Reusable regeneration Restores one Red Heart of Isaac's health. 1
Clicker 5.100.482
Clicker
6 rooms
Change Transforms Isaac into a random character and removes the last item collected. 0
Potato Peeler 5.100.487
Potato Peeler
Unlimited
A pound of flesh Removes a Heart Container, increases damage and range, and grants a 15►Cube of Meat Cube of Meat. 3
Yuck Heart 5.100.639
Yuck Heart
6 rooms
Gross! Gives Isaac a Rotten Heart. 3

Passive Collectibles[]

Name ID Icon Quote Description Quality
<3 5.100.15 <3 HP up Grants Isaac one Red Heart container and fully restores Isaac's health. 2
A Snack 5.100.346 A Snack HP up Grants one full Red Heart container. Added in Repentance Heals 1 additional heart of health. 1
Anemic 5.100.214 Anemic Toxic blood Increases range. After Isaac is damaged, a trail of red creep will be left behind him until he leaves the current room. 0
Ankh 5.100.161 Ankh Eternal life? Upon death, the player will respawn as ??? ??? with 3 Soul Hearts. 2
Aries 5.100.300 Aries Ramming speed +0.25 Speed. Running into enemies while at a high speed will deal damage. Removed in Repentance Does not prevent contact damage. 1
Black Lotus 5.100.226 Black Lotus HP up x3! Grants one Red Heart, one Soul Heart, and one Black Heart. 2
Blood Bag 5.100.119 Blood Bag HP up Grants one Red Heart container, restores 5 Red Hearts, and increases speed by 0.3. 2
Bloody Lust 5.100.157 Bloody Lust RAGE! Increases Isaac's damage whenever he takes damage, up to six times. The bonus resets when entering a new floor. 3
Breakfast 5.100.25 Breakfast HP up Grants one full Red Heart container. Added in Repentance Heals 1 additional heart of health. 1
Bucket of Lard 5.100.129 Bucket of Lard HP up Grants two Removed in Repentanceempty Added in Repentancefull Red Heart containers and heals Isaac by half a Red Heart, but decreases speed by 0.2. 1
Cancer 5.100.301 Cancer HP up + you feel protected Adds 3 Soul Hearts. Grants 15►The Wafer The Wafer effect for the current room after taking damage. 3
Celtic Cross 5.100.162 Celtic Cross Blessing of protection Grants a chance to trigger the 15►Book of Shadows Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds. 1
Charm of the Vampire 5.100.62 Charm of the Vampire Kills heal Heals Isaac for half of a Red Heart for every 13 enemies killed. Added in Repentance +0.3 damage. 0
Dead Bird 5.100.117 Dead Bird Protective buddy After Isaac takes damage, spawns a flying familiar that chases enemies for the current room, dealing ~5 damage per second. 0
Dead Dove 5.100.185 Dead Dove Flight + spectral tears Grants spectral tears and flight. 3
Dessert 5.100.24 Dessert HP up Grants one full Red Heart container. Added in Repentance Heals 1 additional heart of health. 1
Dinner 5.100.23 Dinner HP up Grants one full Red Heart container. Added in Repentance Heals 1 additional heart of health. 1
E Coli 5.100.236 E Coli Turdy touch Enemies that touch Isaac are transformed into poop. 1
Fanny Pack 5.100.204 Fanny Pack Filled with goodies Has a chance to drop a random pickup when Isaac takes damage. 1
Fate 5.100.179 Fate Flight eternal Grants flight and one Eternal Heart. 3
Gimpy 5.100.225 Gimpy Sweet suffering Gives chance of spawning a Soul Heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed. 2
Habit 5.100.156 Habit Item martyr When Isaac is hit, his active item gains 1 room's worth of charge. 3
Holy Grail 5.100.184 Holy Grail Flight + HP up Grants flight and one Red Heart container. 3
Holy Water 5.100.178 Holy Water Splash! Removed in Repentance Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep.
Added in Repentance A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies.
0
Isaac's Heart 5.100.276 Isaac's Heart Protect it Isaac himself is now immune to all damage, and a heart familiar follows him. If the heart is hurt, Isaac is hurt. Added in Repentance The heart charges up as Isaac shoots, firing 8 blood shots, knocking back enemies, and leaving a puddle of creep when released. 0
Judas' Shadow 5.100.311 Judas' Shadow Sweet revenge Adds an extra life; upon death, it respawns Isaac as Dark Judas Dark Judas with two Black Hearts. 4
Lazarus' Rags 5.100.332 Lazarus' Rags Eternal life? Upon dying, resurrect as Lazarus Risen Lazarus Risen in the current room with one heart container and 15►Anemic Anemic. 1
Little C.H.A.D. 5.100.96 Little C.H.A.D. Gives kisses Spawns a familiar who drops a Half Red Heart every 3 rooms. 2
Lord of the Pit 5.100.82 Lord of the Pit Demon wings Grants flight and +0.3 speed. 3
Lunch 5.100.22 Lunch HP up Grants one full Red Heart container. Added in Repentance Heals 1 additional heart of health. 1
Maggy's Bow 5.100.312 Maggy's Bow HP up + you feel healthy Gives one Red Heart container and doubles the healing provided by Red Hearts. 2
Magic Scab 5.100.253 Magic Scab HP + luck up Grants one full Red Heart container, +1 luck. 2
MEAT! 5.100.193 MEAT! DMG + HP up Grants one full Red Heart container, +0.3 damage. 2
Midas' Touch 5.100.202 Midas' Touch Golden touch Enemies that touch Isaac are temporarily petrified and turn to gold. Any enemy killed while in this state will drop coins. 2
Missing Page 2 5.100.262 Missing Page 2 Evil up. Your enemies will pay! Grants one Black Heart. Upon taking damage that reduces Isaac's health to one heart or less, deals damage to all enemies in the room. Added in Repentance Increases the damage of Black Hearts and 15►The Necronomicon The Necronomicon-like effects by 40. 0
Old Bandage 5.100.219 Old Bandage HP up Grants an empty Red Heart container. Adds a chance of dropping a Red Heart after taking damage. 2
Ouija Board 5.100.115 Ouija Board Spectral tears Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them. 2
Piggy Bank 5.100.227 Piggy Bank My life savings Gives 3 pennies on pick-up. Every time Isaac is damaged, he will drop one additional penny. 1
Placenta 5.100.218 Placenta Regeneration + HP up Grants one full Red Heart container, and a chance to regenerate a Half Red Heart of health every minute of gameplay. 2
Raw Liver 5.100.16 Raw Liver HP up Grants 2 Red Heart containers and completely restores health. 2
Rosary 5.100.72 Rosary Tears + faith up Adds 3 Soul Hearts. The Bible will appear in any item pool.
Added in RepentanceAlso a +0.5 tears up.
1
Rotten Meat 5.100.26 Rotten Meat HP up Grants one full Red Heart container. Added in Repentance Heals 1 additional heart of health. 1
Scapular 5.100.142 Scapular Pray for a miracle Once per room, when Isaac is reduced to his last half heart, he is granted one Soul Heart. 2
Sharp Plug 5.100.205 Sharp Plug Infinite charge... at a cost Damages Isaac in exchange for fully recharging Isaac's current activated item. 1
Spiderbaby 5.100.211 Spiderbaby Spider revenge Removed in Repentance When hit, spawns 1-2 Blue Spiders.
Added in Repentance When hit, spawns 3-5 Blue Spiders.
1
Spirit of the Night 5.100.159 Spirit of the Night Scary Grants spectral tears and flight. 3
Stem Cells 5.100.176 Stem Cells HP + shot speed up Grants one full Red Heart container and +0.16 shot speed. 1
Super Bandage 5.100.92 Super Bandage +2 hearts Grants one full Red Heart container and 2 Soul Hearts. 2
The Black Bean 5.100.180 The Black Bean Toot on touch When taking damage, Isaac farts, causing poison damage to all enemies in range. 0
The Body 5.100.334 The Body I feel all Adds 3 Red Heart Containers. 3
The Ladder 5.100.60 The Ladder Building bridges Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections. 1
The Relic 5.100.98 The Relic Soul generator Spawns a cross familiar that drops a Soul Heart every 5-6 rooms. 4
The Virus 5.100.13 The Virus Poison touch + speed up Isaac poisons enemies on contact. Removed in Repentance -0.1 speed. Added in Repentance +0.2 speed. Added in Afterbirth / Removed in Repentance Poisoned enemies have a chance to drop a black heart when killed. 0
The Wafer 5.100.108 The Wafer Damage resistance All sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead. 4
Thunder Thighs 5.100.314 Thunder Thighs HP up + speed down + you feel stompy Destroys rocks upon contact with Isaac. Adds one Red Heart container and lowers Speed. 1
Transcendence 5.100.20 Transcendence We all float down here... Grants flight. 3
Athame 5.100.408 Athame Call to the void When Isaac takes damage, a black ring briefly appears around him, dealing damage to all nearby enemies. 2
Betrayal 5.100.391 Betrayal Turn your enemy Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac. 0
Cambion Conception 5.100.412 Cambion Conception Feed them hate After taking damage a certain amount of times, a permanent demonic familiar spawns. 2
Crack Jacks 5.100.354 Crack Jacks HP up. Don't swallow the prize! Grants one full Red Heart container and drops a random trinket. 2
Curse of the Tower 5.100.371 Curse of the Tower Embrace chaos Upon taking damage, spawns six Troll Bombs around the room, similar to the effect of XVI - The Tower XVI - The Tower. 1
Immaculate Conception 5.100.413 Immaculate Conception Feed them love Upon picking up a certain amount of health, spawn a permanent angelic familiar. 1
Milk! 5.100.436 Milk! Don't cry over it... Spawns a glass familiar that spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the current room. 1
My Shadow 5.100.433 My Shadow Me! And my shaaaadow! Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black friendly Charger that will attack enemies. The Charger will be killed if it is damaged too much. 0
PJs 5.100.428 PJs You feel cozy Grants 4 Soul Hearts and fully restores Isaac's health. 2
Adrenaline 5.100.493 Adrenaline Panic = power Increases damage based on how many empty Red Heart containers Isaac has. 1
Bozo 5.100.513 Bozo Party time! +0.1 flat damage, grants a Soul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop. 2
Brittle Bones 5.100.549 Brittle Bones Everything hurts Replaces all Red Hearts with 6 empty Bone Hearts. Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a tears up. 3
Dark Prince's Crown 5.100.442 Dark Prince's Crown Loss is power When at exactly one Red Heart, increases tears, range, tear height, and shot speed. 1
Hallowed Ground 5.100.543 Hallowed Ground Portable sanctuary Spawns a white poop familiar, which turns into a white poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. 1
Leprosy 5.100.525 Leprosy You're tearing me apart! Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots. 1
Marrow 5.100.541 Marrow HP up? Grants one bone heart and spawns three red heart pickups. 1
Midnight Snack 5.100.456 Midnight Snack HP up Grants one full Red Heart container. Added in Repentance Heals 1 additional heart of health. 1
Mystery Egg 5.100.539 Mystery Egg Sacrificial insemination Spawns an egg familiar, which cracks into a random friendly monster when Isaac is hurt. The egg regenerates upon entering a different room. 1
Varicose Veins 5.100.452 Varicose Veins I'm leaking... Taking damage releases a ring of 10 high damage tears. 2
Astral Projection 5.100.677 Astral Projection The true out-of-body experience! Causes Isaac to turn into a ghost if he gets hit while in an uncleared room, giving him flight and spectral tears and blocking the next hit he takes. 2
Binge Eater 5.100.664 Binge Eater All you can eat +1 red heart container and fully heals Isaac. Item pedestals cycle between their normal items and food, and collecting food grants a temporary damage boost and permanent bonuses to 2 stats. 3
Bird Cage 5.100.610 Bird Cage Fat buddy The first time Isaac takes damage in a room, a familiar leaps on an enemy, dealing damage and releasing a rock wave. For the rest of the room, it chases enemies similar to 15►Dead Bird Dead Bird. 1
Blood Oath 5.100.569 Blood Oath Bleed me dry Stabs Isaac at the beginning of each floor, draining his red hearts. Increases damage and speed for the floor based on the amount drained. 2
Bloody Gust 5.100.695 Bloody Gust May your rage bring haste When Isaac takes damage, he gains speed and tears for the rest of the floor. 3
Candy Heart 5.100.671 Candy Heart Power of love Gives Isaac a permanent stat boost whenever he heals with red heart pickups. 2
Cracked Orb 5.100.675 Cracked Orb Shards of knowledge Unlocks doors and reveals a random room on the map when Isaac takes damage. 1
Empty Heart 5.100.676 Empty Heart It multiplies If Isaac has one red heart or less at the beginning of a floor, he gains an empty red heart container. 2
Giant Cell 5.100.658 Giant Cell Micro friends Causes Isaac to spawn micro-Isaacs when he takes damage, which chase and shoot at nearby enemies. 1
Heartbreak 5.100.694 Heartbreak Eternal sorrow Grants 3 broken hearts and +0.25 damage for every broken heart Isaac has. Every otherwise fatal hit will add 2 more until Isaac has nothing but broken hearts. 3
It Hurts 5.100.560 It Hurts No it doesn't... Releases a ring of tears and increases tears for the current room when Isaac takes damage. 1
Orphan Socks 5.100.571 Orphan Socks Speed up + your feet feel stronger Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 soul hearts. 1
Sanguine Bond 5.100.692 Sanguine Bond He awaits your offering Spawns a special set of spikes in the Devil Room Devil Room. Taking damage from the spikes has a chance to grant a reward. 1
Supper 5.100.707 Supper HP up Grants one full Red Heart container. Heals 1 additional heart of health. 1
Vengeful Spirit 5.100.702 Vengeful Spirit Hot blooded After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots. 2
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