Items with this tag grant the Yes Mother? transformation.
Activated Collectibles[]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Mom's Bottle of Pills | 5.100.102 |  
|
Reusable pill generator | Gives Isaac a random pill. | 1 |
| Mom's Bra | 5.100.39 |  
|
Mass paralysis | Petrifies all enemies in the current room for around 4 seconds. | 1 |
| Mom's Pad | 5.100.41 | 
|
Mass fear | Inflicts fear to all enemies in the room for 5 seconds. | 0 |
| Mom's Box | 5.100.439 |  
|
What's inside? | Increases Luck by 1 and doubles the effects of trinkets while held. When used, drops a random trinket on the ground. | 3 |
| Mom's Shovel | 5.100.552 | 
|
Lost but not forgotten | Spawns a trapdoor that leads to the next floor upon activation. Unlocks The Forgotten when used on a mound of dirt that appears in  Dark Room.
|
4 |
| Mom's Bracelet | 5.100.604 |  
|
Mother's strength | Lets Isaac pick up and throw rocks, TNT, poops, and other obstacles. | 2 |
Passive Collectibles[]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Mom's Coin Purse | 5.100.195 | 
|
What's all this...? | Spawns 4 random pills near Isaac. | 1 |
| Mom's Contacts | 5.100.110 | 
|
Freeze effect | +0.25 range. Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. | 3 |
| Mom's Eye | 5.100.55 | 
|
Eye in the back of your head | Gives Isaac a chance to fire tears from the back of his head. | 1 |
| Mom's Eyeshadow | 5.100.200 | 
|
Charm tears | Tears have a chance to charm enemies. | 1 |
| Mom's Heels | 5.100.30 | 
|
Range up | +5.25 range, +0.5 tear height. Enemies that touch Isaac take 12 damage.
|
1 |
| Mom's Key | 5.100.199 | 
|
Better chest loot +2 keys | Adds 2 keys. Chests will drop additional pickups. | 3 |
| Mom's Knife | 5.100.114 | 
|
Stab stab stab | Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power. | 4 |
| Mom's Lipstick | 5.100.31 | 
|
Range up | +5.25 range, +0.5 tear height. Spawns one random heart.
|
1 |
| Mom's Perfume | 5.100.228 | 
|
Fear shot + tears up | Adds a chance to shoot fear tears and decreases tear delay by 1. | 2 |
| Mom's Purse | 5.100.139 | 
|
More trinket room | Allows Isaac to hold 1 additional trinket. | 3 |
| Mom's Underwear | 5.100.29 | 
|
Range up | +5.25 range, +0.5 tear height. Spawns 3-6 Blue Flies on pickup.
|
1 |
| Mom's Wig | 5.100.217 | 
|
You feel itchy... | Adds a chance to spawn Blue Spiders when firing tears. Restores 1 red heart. | 3 |
| Mom's Pearls | 5.100.355 | 
|
Range + luck up | +1.25 range, +0.5 tear height, +1 luck. Grants one Soul Heart.
|
2 |
| Mom's Razor | 5.100.508 | 
|
It's sharp! | Spawns an orbiting razor that deals contact damage and inflicts bleeding on enemies, causing them to slowly take damage over time. | 1 |
