Items with this tag contribute toward the Guppy transformation.
Activated Collectibles[]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Guppy's Head | 5.100.145 |  
|
Reusable fly hive | Spawns 2-4 friendly Blue Flies that damage enemies. | 2 |
| Guppy's Paw | 5.100.133 |  
|
Soul converter | Converts one Red Heart Container into three  Soul Hearts.
|
3 |
Passive Collectibles[]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Dead Cat | 5.100.81 | 
|
9 lives | Sets Isaac's Red Heart Containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container. | 3 |
| Guppy's Collar | 5.100.212 | 
|
Eternal life? | Grants a permanent 50% chance to respawn with 1/2 of a  Red Heart after death.
|
1 |
| Guppy's Hairball | 5.100.187 | 
|
Swing it | Spawns a familiar that loosely follows behind Isaac, which blocks shots can be swung like a flail to damage enemies. Grows bigger by killing enemies. | 1 |
| Guppy's Tail | 5.100.134 | 
|
Cursed? | Room Clear Awards have a 1/3 chance of being replaced with a  Chest and a 2/9 chance being replaced with nothing.
|
2 |
| Guppy's Eye | 5.100.665 | 
|
An eye for secrets | Shows the contents of Chests,  Fire Places,  Grab Bags, and  Shopkeepers before they're opened/destroyed.
|
2 |
 The Binding of Isaac: Rebirth
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