Items with this tag unlock 
The Parasite.
Activated Collectibles[]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Bob's Rotten Head | 5.100.42 |  
|
Reusable ranged bomb | Upon use, Isaac holds a poison bomb which can be thrown in the cardinal directions and explodes on impact. | 1 |
| Guppy's Head | 5.100.145 |  
|
Reusable fly hive | Spawns 2-4 friendly Blue Flies that damage enemies. | 3 |
| Guppy's Paw | 5.100.133 |  
|
Soul converter | Upon use, converts one Red Heart Container into three Soul Hearts. | 3 |
| Tammy's Head | 5.100.38 | 
|
Reusable tear burst | Shoots 10 tears in a circle around Isaac, which retain the Damage, Shot Speed, and special effects (such as poison) of Isaac's tears. | 3 |
Passive Collectibles[]
| Name | ID | Icon | Quote | Description | Quality |
|---|---|---|---|---|---|
| Cricket's Body | 5.100.224 | 
|
Bursting shots + tears up | Grants -1 tear delay and reduces range. When tears hit an object or deplete their range, they spawn 4 smaller tears, whose range and damage scale with Isaac's. | 3 |
| Cricket's Head | 5.100.4 | 
|
DMG up | Increases Damage by 0.5, and increases damage multiplier by x1.5. | 4 |
| Dead Bird | 5.100.117 | 
|
Protective buddy | After Isaac takes damage, spawns a flying familiar that chases enemies for the current room, dealing ~5 damage per second. | 0 |
| Dead Cat | 5.100.81 | 
|
9 lives | Sets Isaac's Red Heart containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container. | 3 |
| Dead Onion | 5.100.336 | 
|
Toxic aura tears | Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed. | 3 |
| Guppy's Tail | 5.100.134 | 
|
Cursed? | Room Clear Awards have a 1/3 chance of being replaced with a Chest and a 1/3 chance being replaced with nothing. | 2 |
| Bird Cage | 5.100.610 | 
|
Fat buddy | The first time Isaac takes damage in a room, a familiar leaps on an enemy, dealing damage and releasing a rock wave. For the rest of the room, it chases enemies similar to  Dead Bird.
|
1 |
| Strawman | 5.100.667 | 
|
A helping hand | Spawns a controllable  Keeper to fight enemies alongside Isaac, functioning similarly to  Jacob and Esau. If Keeper dies, he spawns 5 blue spiders and Strawman is removed from Isaac's inventory.
|
2 |
