This article is about the character. For the boss of The Cathedral, see Isaac (Boss).
Isaac is the main character of the series, reappearing from the original Binding of Isaac. Isaac is the only character unlocked by default.
Isaac starts with three Red Heart containers and one bomb. He will also start with 
The D6 once it is unlocked (after defeating Isaac as ???).
Notes
Unlockable Achievements
Gallery
Original concept art for a character who would eventually be remodeled to Isaac.
Trivia
- Isaac is a reference to the biblical story of the binding of Isaac, in which Abraham is commanded by God to sacrifice his only son, Isaac, to prove his loyalty and love.
- "Then God said, 'Take your son, your only son, whom you love — Isaac — and go to the region of Moriah. Sacrifice him there as a burnt offering on a mountain I will show you.'" (Genesis 22:2)
- In a response to TBoI Youtuber Sinvicta of whether there was any concept art of what Isaac's original design was, Edmund McMillen confirmed that Isaac's design was originally one of an Octorock while showing very similar features of how the gameplay would be modeled by posting an old concept art.
- Edmund has stated that Isaac is left-handed, but in the opening cutscene, Isaac is holding a pencil with his right hand.[1]
- This could be a reference to the Catholic bias against left-handedness, stemming from Matthew 25:33 proclaiming that God will put those deserving to ascend to Heaven on his right-hand side and put those deserving to descend to Hell on his left-hand side. Isaac's mother could have forced him to learn things the "righty" way for fear of him being "evil."
- Contrary to previous theories made about Isaac, he does not have a sister.
- Isaac is bald because his mother shaved his head. Which could be a reference to the Nazarite Vow in Numbers 6:1–21 [2]
- Isaac has Irritable Bowel Syndrome. [3]
- Isaac's dad is a handy man. [4]
- Isaac's full name is Isaac Moriah. [5]
- This is in reference of Mount Moriah, the place where Abraham takes his son Isaac to be sacrificed, in the Book of Genesis.
- Isaac is 5 years old. [6]
References
- ↑ http://4ms.me/165we0q
- ↑ http://edmundm.com/post/73658340217/why-is-isaac-bald-did-his-mother-shave-his-head-when
- ↑ https://twitter.com/edmundmcmillen/status/1162808018943135744
- ↑ https://twitter.com/onionsunleashed/status/1318739388982087680
- ↑ https://twitter.com/edmundmcmillen/status/1321659391297294336
- ↑ https://twitter.com/edmundmcmillen/status/1321659391297294336
 Characters
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 The Binding of Isaac: Rebirth
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