Binding of Isaac: Rebirth Wiki
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Infestation is a passive item.

Effects

  • (except in Repentance) 1-3 Blue Flies randomly spawn whenever Isaac takes damage.
  • (in Repentance) 2-6 Blue Flies randomly spawn whenever Isaac takes damage.

Interactions

  • (in Afterbirth † and Repentance)Fish TailFish Tail: Doubles number of flies spawned.
  • Collectible Hive Mind iconHive Mind: Flies are bigger and deal double damage.

In-game Footage

Trivia

  • (except in Repentance) Prior to Repentance, this item's description was "They grow inside".

Seeds

PC Normal mode only 8H3N AE8H (Treasure Room adjacent to spawn)

PC CW0L S1LN (Treasure Room in one room above the spawn)

PC 33QM WGYC (Treasure Room in one room above the spawn)

PS4 QZ8P 4BQF (Treasure Room adjacent to spawn)

PS4 2VP2 JVWH (Treasure Room two rooms above spawn)

PS4 SAPZ YHX0 (First floor treasure room)

3DS LBXS W367 (Treasure Room adjacent to spawn)


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