Binding of Isaac: Rebirth Wiki
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Infestation is a passive item.

Effects[ | ]

  • (except in Repentance) 1-3 Blue Flies spawn whenever Isaac takes damage.
  • (in Repentance) 2-6 Blue Flies spawn whenever Isaac takes damage.

Interactions[ | ]

  • (in Afterbirth † and Repentance)Fish TailFish Tail: Doubles number of flies spawned.
  • Collectible Hive Mind iconHive Mind: Flies are bigger and deal double damage.

In-game Footage[ | ]

Trivia[ | ]

  • (except in Repentance) Prior to Repentance, this item's description was "They grow inside".


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