Binding of Isaac: Rebirth Wiki

Infestation is a passive item.

Effects[]

  • (except in Repentance) 1-3 Blue Flies spawn whenever Isaac takes damage.
  • (in Repentance) 2-6 Blue Flies spawn whenever Isaac takes damage.

Interactions[]

  • (in Afterbirth † and Repentance) Fish TailFish Tail: Doubles number of flies spawned.
  • Hive Mind: Flies are bigger and deal double damage.

In-game Footage[]

Trivia[]

  • (except in Repentance) Prior to Repentance, this item's description was "They grow inside".