Immaculate Conception

 

"Feed them love"

Item ID
5.100.413

Character Appearance

Item Pool

			Angel Room
			Angel Room

Collection Grid

(page 4, column 8, row 3)

(page 4, column 8, row 3)

(page 4, column 9, row 3)

Unlock Method
Complete the Boss Rush as Lilith

Immaculate Conception is an unlockable passive item added in The Binding of Isaac: Afterbirth.

Effects

• Upon picking up enough heart pickups, Isaac gains a permanent angelic familiar and generates a Soul Heart drop. Possible familiars include:
  • Holy Water
  • Guardian Angel
  • Sworn Protector
  • The Relic
  • Seraphim
• All five familiars will spawn in a random order, each after collecting 15 hearts.
• After all familiars have been spawned, a Soul Heart will still drop every 15 hearts collected.
• Isaac will look progressively more pregnant as he collects hearts pickups.

Notes

• All types of hearts except Gold Hearts and Blended Hearts count.
• Items that directly add health such as Yum Heart, Book of Revelations, Satanic Bible, and The Nail do not count towards spawning a familiar.
• Only one of each type of familiar can be spawned.
• This item is the angelic counterpart to Cambion Conception.
• The Lost can pick up Soul Hearts and Black Hearts despite having no health and thus can activate Immaculate Conception.
• Keeper cannot encounter hearts and thus the item is useless for him.

Interactions

• The Jar: Hearts collected in the jar do not count towards activation.

Trivia

• Immaculate Conception refers to the Catholic teaching that the conception of the Virgin Mary was free from original sin.