Binding of Isaac: Rebirth Wiki
Character Isaac appearance.png
Full red heartFull red heartFull red heart
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Challenge Number
Available Rooms
Item Pool Treasure Room.png: no          Item Pool Shop.png: yes
Boss Mega Satan portrait.png
Poker Chip Poker Chip
Unlock Method

I RULE! Removed in Repentance Defeat ??? or The Lamb, and defeat Satan as Isaac Isaac
Added in Repentance Defeat Mega Satan

Added in Afterbirth

I RULE! is challenge #26. Isaac starts off with Key Piece 1 Key Piece 1, Key Piece 2 Key Piece 2, Trinity Shield Trinity Shield, Mom's Knife Mom's Knife, The Ladder The Ladder, and The Boomerang The Boomerang. The goal is to defeat Mega Satan Mega Satan. The Boss Room containing ??? ??? or The Lamb The Lamb does not appear.


With a powerful set of items to start with, this is a rather easy challenge after getting used to Mom's Knife. The most difficult challenge here is defeating Mega Satan.


  • Because Mom's Knife overrides many other items, finding powerful synergies may prove challenging.
  • As a result of beginning the challenge with both Key Pieces, Angel Rooms are much more likely to appear than normal.
  • Removed in Afterbirth † It is somewhat easier to beat this challenge with The Polaroid The Polaroid (which doesn't appear after the Mom fight in Afterbirth †) than it is with The Negative The Negative, as Isaac Isaac is an easier fight than Satan Satan in this challenge. Furthermore, the Chest Chest can provide many chances at useful items that the Dark Room Dark Room does not.
  • Added in Repentance The Red Chest Red Chests in the Dark Room now offer Devil Deals, granting powerful items at the cost of Red Heart Containers.


  • Aside from beating Mega Satan Mega Satan for the first time, the player must also unlock all starter items in the challenge. That is, ??? ??? or The Lamb The Lamb must be beaten to unlock the Key Pieces (which is a prerequisite requirement to defeat Mega Satan Mega Satan anyway) and Satan Satan must be beaten with Isaac Isaac to unlock Mom's Knife Mom's Knife. In addition, although not explicitly stated, The Negative The Negative must also be unlocked by defeating Satan Satan 5 times, as the challenge requires you to go to the Dark Room Dark Room and then fight Mega Satan Mega Satan. Mega Satan can be defeated before unlocking The Negative The Negative and vice versa; the challenge will be unlocked immediately once all requirements are met.
  • Removed in Repentance Despite being forced to take The Negative The Negative, the Cathedral Cathedral can still be accessed; however, once Isaac Isaac is defeated and the chest is entered, the run will simply end and will not count as a completion of the challenge.
  • If the player starts the challenge before The Polaroid The Polaroid and The Negative The Negative have been unlocked (using I AM ERROR I AM ERROR, a Sacrifice Room Sacrifice Room, We Need to Go Deeper! We Need to Go Deeper!, etc.) then the player will need to repeat said method or use another method to advance to Mega Satan.
  • Added in Afterbirth † Killing Delirium Delirium will count as completing the challenge.



  • This challenge is a homage to the original The Legend of Zelda, which this game is inspired by.
    • The items given in this challenge are meant to replicate Link's equipment from said game.
    • The title of the challenge is a play on "Hyrule", the kingdom in which most Zelda games take place.