Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki
Special Cards
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Added in Afterbirth †

The Holy Card is a special card added in The Binding of Isaac: Afterbirth †.


  • Grants a one-time 15►Holy Mantle Holy Mantle effect.
    • Removed in Repentance This only applies for the current room.
    • Added in Repentance The effect lasts until damage is taken.
  • Removed in Repentance Has a 25% chance to display the message "You feel blessed!" and spawn another Holy Card.


  • The effect cannot be stacked by using multiple Holy Cards.
  • Added in Repentance Tainted Lost Tainted Lost starts with this card. Additionally, Holy Cards are significantly more common when playing as this character and can be found even if they have not been unlocked.


  • 15►Blanket Blanket: Holy Card's effect takes priority over the shield from Blanket in boss rooms.
  • 15►Holy Mantle Holy Mantle: Effect stacks with Holy Card.
  • Wooden Cross Wooden Cross: Does not stack with Holy Card; both are treated as the same shield.


Bug Bug! When using the D4, or another item / room which mimics it, the Holy Card effect will be permanently lost. This can result in unintentional death for Tainted Lost.

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