Binding of Isaac: Rebirth Wiki
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(in Afterbirth † and Repentance)

The Holy Card is a special card added in The Binding of Isaac: Afterbirth †.

Effects[ | ]

  • Grants a one-time Collectible Holy Mantle iconHoly Mantle effect.
    • (except in Repentance) This only applies for the current room.
    • (in Repentance) The effect lasts until damage is taken.
  • (except in Repentance) Has a 25% chance to display the message "You feel blessed!" and spawn another Holy Card.

Notes[ | ]

  • The effect cannot be stacked by using multiple Holy Cards.
  • (in Repentance) Character Tainted Lost iconTainted Lost starts with this card. Additionally, Holy Cards are significantly more common when playing as this character and can be found even if they have not been unlocked.

Interactions[ | ]

  • Collectible Blanket iconBlanket: Holy Card's effect takes priority over the shield from Blanket in Boss RoomBoss Rooms.
  • Collectible Holy Mantle iconHoly Mantle: Effect stacks with Holy Card.
  • Wooden CrossWooden Cross: Stacks with Holy Card depending on the order of use. If Wooden Cross is picked up after Holy Card has been used, their effects don't stack. If Holy Card is used after Wooden Cross has been picked up, they do. The stacking only lasts for the current room.
  • Collectible Little Baggy iconLittle Baggy: Will make Isaac unable to find Holy Cards, as all cards turn into pills. If Holy Card is dropped after taking Little Baggy, the Holy Card will turn into a random pill.


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