Hive Mind is a passive item.
Effects[ | ]
- Increases the size and doubles the damage of Blue Spiders, Blue Flies and
Locusts. - Fly and spider familiars become stronger, exactly like BFFS!.
- This item belongs to the Beelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.
- This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.
Fly and spider familiars become stronger, exactly like 
Notes[ | ]
- This item does not affect Fly familiars or orbitals.
- No effect on flies made passive by Skatole.
This item does not affect Fly familiars or orbitals.
Synergies[ | ]
- Guppy: Doubles the damage of all Blue Flies spawned greatly increasing damage output.
- Brown Nugget: Turret does 7 damage instead of 3.5
- Mom's Wig: Doubles spider limit of the wig to 10 spiders.
- Plum Flute: Doubles Baby Plum's contact damage, but not projectile damage. Plum is also larger.
- Red Locusts: Contact damage is doubled as normal and explosions will deal an additional 25 flat damage.
- Sissy Longlegs: Increases familiar's size. Spiders spawned by Sissy are affected by Hive Mind.
Interactions[ | ]
- BFFS!: Does not give any additional benefit to fly and spider familiars.
In-game Footage[ | ]
Trivia[ | ]
- Hive mind is the concept of a large number of beings acting in the interest of the survival of the group as a whole, with little to no individuality.
- This item is one of the only five that count towards 2 transformations, the other four being Skatole, The Bible, Magic Mushroom and Parasitoid.
 Familiar Modifiers
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| Items |
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| Trinkets |
 Fly Items
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| Items |
 The Binding of Isaac: Rebirth
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