Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Repentance

Hemoptysis is a passive item added in The Binding of Isaac: Repentance.


  • Double-tapping a fire button causes Isaac to sneeze blood, dealing damage to enemies in front of him. The sneeze deals damage equal to 1.5x Isaac's damage and pushes enemies and their projectiles back. If the enemy is pushed into a wall/obstacle, they take 10 damage and deal 10 damage to enemies they collide with.
    • The sneeze has a cooldown of 1 second.


  • Tainted Azazel Tainted Azazel has a mechanic similar to Hemoptysis.
    • This version of Hemoptysis allows him to deal full brimstone damage to enemies, which were damaged with sneeze before.
  • The sneeze's range is affected by the shot speed stat, and not by the range stat itself.
  • The sneeze can push Bombs.
  • The collision damage can be used to damage Hosts while their skulls are lowered.



  • Ipecac Ipecac: The sneeze causes an explosion. The explosion deals additional damage equal to 3x Isaac's damage +10 and will not hurt Isaac.

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  • Hemoptysis is the medical term for coughing up blood.