Guppy's Tail

"Cursed?"
Entity ID	5.100.134
Character Appearance
Item Pool	Curse Room Devil Room Red Chest Curse Room Devil Room
Collection Grid	(page 2, column 1, row 4) (page 2, column 11, row 1)

Guppy's Tail is a passive item.

Effects

• Grants a 1/3 chance of replacing a room clear award with a normal chest or a locked chest, but also a 1/3 chance to replace it with nothing at all.
  • The effect does not apply to coins dropped in Greed Mode.
• This item belongs to the Guppy set. Collecting three items from this set will transform Isaac into Guppy.

Notes

• The drawback to this item is that keys become much more scarce, while increasing the amount of locked chests. This makes taking Guppy's Tail a potential liability early on.
• Due to any found chests containing items while in Chest or Dark Room, Guppy's Tail can be a good way to quickly stack up more upgrades before facing the final boss.

Synergies

• Guppy's Eye: Makes key management easier by revealing which golden chests are worth opening and which are not.
• The Left Hand: Turns all chests into Red Chests, allowing you to get Red Chest items much more quickly (including Guppy items).
• Mom's Key: Increases the number of drops from chests and counteracts the increased chance to run into Locked Chests.

Trivia

• This item is used in Cat Got Your Tongue (challenge #8).

Pet Items

Cricket:

• Cricket's Body
• Cricket's Head

Guppy:

• Dead Cat
• Guppy's Collar
• Guppy's Eye
• Guppy's Hair Ball
• Guppy's Head
• Guppy's Paw
• Guppy's Tail
• Kid's Drawing

Tammy:

• Tammy's Head