Guppy's Head

"Reusable fly hive"

Item ID
5.100.145

Recharge Time

Collection Grid
(page 2, column 2, row 5)
(page 2, column 2, row 2)


Guppy's Head is an activated item.
Effects[edit | edit source]
- Spawns 2-4 friendly Blue Flies.
- This item belongs to the Guppy set. Collecting three items from this set will transform Isaac into Guppy.
Notes[edit | edit source]
- Each Blue Fly deals 2x Isaac's damage.
Box of Spiders is essentially the spider equivalent to Guppy's Head, but can be activated less often.
Synergies[edit | edit source]
Car Battery: Spawns more Blue Flies per use.
Hive Mind: Increases size and damage of Blue Flies.
In-game Footage[edit | edit source]
Trivia[edit | edit source]
- This item is used in Cat Got Your Tongue (challenge #8).
Gallery[edit | edit source]
Seeds[edit | edit source]
PC TK1W XHLH (first Curse Room)
PS4 J304 8T8Y (first Curse Room)
Pet Items
Cricket:
Dead Cat
Guppy's Collar
Guppy's Eye
Guppy's Hair Ball
Guppy's Head
Guppy's Paw
Guppy's Tail
Kid's Drawing
Tammy:
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