Guillotine

Guillotine is an unlockable passive item.

Effects[]

Isaac's head becomes an orbital familiar that blocks shots and deals contact damage. Tears are still fired from the rotating head.
+1 damage.
-1 tear delay (increased rate of fire)
- Since this directly affects tear delay instead of changing the tears stat, it allows Isaac's rate of fire to go over the normal maximum rate.
- Tear delay decreases are more noticeable and are a greater increase to DPS when the tears stat is high.
+0.5 fire rate.
The head orbital deals 7 damage per tick or 105 damage per second.
The head orbital deals 7 damage per tick or 56 damage per second.

Isaac's body will spew a fountain of blood like a Gusher. This is purely cosmetic.
While Isaac's actual hitbox (his body) does not change, the position of the head can obscure the body's exact position, making things such as dodging or collecting pickups more difficult.
Items that apply contact damage and effects (The Virus, Aries, etc.) do not apply to the head.
The head orbital ignores the normal three orbital cap used by items such as Cube of Meat and Sacrificial Dagger.
The orbital is larger than most other orbitals, making it easier to use both offensively and defensively.
- Despite changing size with Isaac, the orbital's hitbox does not change, which can be deceptive.
Standing near a wall may cause the head to go inside the wall while rotating, blocking tears.

BFFS!: Although the head doesn't increase in size, doubles the contact damage.
Big Fan: Slows down the head orbital, making it easier to aim.
Guardian Angel: Does not increase the head's rotation speed.
Spectral tears: Prevents shots from being blocked by walls, making it easier to fire.

Overrides Guillotine's firing pattern:

Other interactions:

Box of Friends/ The Twins: Adds another rotating head, but only the original head will fire tears.
Guillotine: Each additional copy adds another orbital and increases stats, but only the original head will fire tears.
Duct Tape: Causes tears to be fired from far below and to the right of Isaac. This causes tears to be out of bounds unless Isaac is standing in the top-left corner of the room.
Duct Tape: Tears are fired from whatever position the head is stuck in.
The Pinking Shears/Transcendence: Removes Isaac's body aside from a small shadow. This can make Isaac's position even more confusing.
Sacrificial Altar: The head orbital cannot be sacrificed.
Scissors: The head created by Scissors fires tears, while the head created by Guillotine only acts as an orbital.
Spin to Win: Affects the head, which boosts its damage and defense properties but makes shots harder to hit.
Tiny Planet: Tears fire from the head and orbit around the body.

A guillotine is an execution device that kills by severing its victim's head. It gained notoriety during the French Revolution where it was used to kill 17,000 people during the period known as the "Reign of Terror."
If Isaac has items that visually change his hands, the effect applies to Isaac's head too. For example, when having Bursting Sack, Isaac's body and head will both hold a sack while there are two extra hands added to the head.