Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Guillotine is an unlockable passive item.


  • Isaac's head rotates around his body and can be used to inflict contact damage similar to a 15►Cube of Meat Cube of Meat. Blocking tears with Isaac's head does not damage Isaac. His tears still originate from his head, so the line of fire is no longer constant while standing still.
  • +1 damage.
  • -1 tear delay (increased rate of fire)
    • Since this directly affects tear delay instead of changing the tears stat, it allows Isaac's rate of fire to go over the normal maximum rate.
    • Tear delay decreases are more noticeable and are a greater increase to DPS when the tears stat is high.
  • The head orbital deals 7 damage per tick or 105 damage per second.


  • In combination with other items, it can exceed a three-orbital cap.
  • The orbital is larger than most other orbitals, making it easier to use both offensively and defensively.
    • Despite changing size with Isaac, the orbital's hitbox does not change which can be deceptive.
  • Using this item while near a wall may cause the head to go inside the wall while rotating and block tears shot.


  • 15►BFFS! BFFS!: Head orbital does not increase in size but it does in damage.
  • Added in Afterbirth15►Box of Friends Box of Friends: Adds another rotating head on each use. Each head increases damage and tears and blocks projectiles. With more heads, it is easier to locate the position of the body, and Box of Friends can be used multiple times in the same room to continue gaining heads.
  • Spectral tears: Guillotine can move Isaac's head into walls, which results in lots of wasted shots. Spectral tears allow all shots to have a chance to hit, instead of being wasted by hitting the wall.
  • Added in RepentanceThe Twins The Twins: Has a chance to add another head, increasing damage and tears.


  • Added in Repentance15►Berserk! Berserk!/Tainted Samson Tainted Samson: The jawbone fires from Isaac's body, not his head.
  • Added in Afterbirth15►Diplopia Diplopia: Adds another head and damage up, but only fires tears from one of them. No further tear delay down.
  • Added in Afterbirth †Duct Tape Duct Tape: Causes tears to be fired from far below and to the right of Isaac. This causes tears to be out of bounds unless Isaac is standing in the top-left corner of the room.
  • The Forgotten: Attacks with the bone club will come from The Forgotten's body, not his head.
  • 15►Mom's Knife Mom's Knife: The knife fires from Isaac's body, not his head.
  • Added in Repentance15►Spirit Sword Spirit Sword: The sword is swung from Isaac's body, not his head. This also applies to the sword's projectiles.
  • Tainted Lilith Tainted Lilith: The baby fires from Isaac's body, not his head.
  • Added in Afterbirth15►Tractor Beam Tractor Beam: The tears fire from Isaac's body, not his head.
  • 15►Transcendence Transcendence: Makes Isaac's body invisible, leaving only a shadow where his body is. As a result, Isaac becomes very difficult to control.
  • Added in Afterbirth †15►Sacrificial Altar Sacrificial Altar: No effect.

In-game Footage[]


  • If Isaac has items that visually change his hands, the effect applies to Isaac's head too. For example, when having Added in Afterbirth15►Bursting Sack Bursting Sack, Isaac's body and head will both hold a sack while there are two extra hands added to the head.


PC Removed in Repentance Normal mode only TR61 X22B (Treasure Room adjacent to spawn)

PC Removed in Repentance Normal mode only V6DK 2AGO (Treasure Room adjacent to spawn)

PC Removed in Repentance SPAM N693 (Treasure Room adjacent to spawn)

PC Removed in Repentance YTDT EJGK (Treasure Room adjacent to spawn)