Guardian Angel is an unlockable passive item.
- Spawns an orbital familiar that blocks enemy shots and deals 7 damage per tick or 105 damage per second on contact.
- Increases the speed of all orbital familiars.
- This item belongs to the Seraphim set. Collecting three items from this set will transform Isaac into an angel.
- This item belongs to the Conjoined set. Collecting three items from this set will transform Isaac into a three-faced version of himself.
- The increased orbital speed improves odds of being protected from enemy shots.
- Big Fan: Guardian Angel counteracts most of the slower orbit speed.
- A guardian angel is a type of angel that is assigned to guide or protect a particular person/group.