Guardian Angel is an unlockable passive item.
Effects[ | ]
- Spawns an orbital familiar that blocks enemy shots and deals 7 damage per tick on contact.
This deals 105 damage per second.- This deals 52.5 damage per second.
- Increases the speed that all orbital familiars rotate around Isaac at.
- This item belongs to the Seraphim set. Collecting three items from this set will transform Isaac into an angel.
- This item belongs to the Conjoined set. Collecting three items from this set will transform Isaac into a three-faced version of himself.
This deals 105 damage per second.
Synergies[ | ]
- Sacrificial Altar: This familiar will also reward 2 Black Hearts when sacrificed.
- Spin to Win: The two orbital speed boosts stack.
Interactions[ | ]
- Big Fan: Overrides Guardian Angel's speed boost. If Guardian Angel was obtained first, it will retain its own increased speed. If Big Fan was obtained first, Guardian Angel will be slower.
In-game Footage[ | ]
Trivia[ | ]
- A guardian angel is a type of angel that is assigned to guide or protect a particular person/group.
 Familiar Modifiers
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 Magdalene Unlocks
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 Satan Unlocks
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 The Binding of Isaac: Rebirth
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