Glyph of Balance

Item Icon
Pickup Quote	"A gift from above"
Entity ID	5.100.464
Character Appearance
Item Pool	Angel Room Angel Room
Quality	2
Item Tags
Collection Grid	(page 4, column 19, row 5) (page 4, column 20, row 5)
Unlock Method	Defeat Ultra Greedier as Magdalene

Glyph of Balance is an unlockable passive item added in The Binding of Isaac: Afterbirth †.

Effects

• Grants 2 Soul Hearts.
• Modifies drops from Champion enemies depending on certain conditions.
• Also modifies room clear drops.
• The priorities of the drops, in order, are as follows:
  • Soul Hearts: When Isaac has no Red Heart containers and less than 2 Soul Hearts.
  • Full Red Hearts: While at 0.5 Red Hearts.
  • Keys: When Isaac has no keys. 
  • Bombs: When Isaac has no bombs.
  • Full Red Hearts: When Isaac has at least half a Red Heart container empty.
  • Pennies: While Isaac has less than 15 pennies.
  • Keys: When Isaac has less than 5 keys. 
  • Bombs: When Isaac has less than 5 bombs.
  • Trinkets: If Isaac has no trinkets and there are no trinkets on the ground in the room.
  • Soul Hearts: When Isaac has less than 6 total Heart containers of any kind.
  • If none of the above conditions are true, items dropped will be rolled as normal.

Notes

• The Glyph has no effect in Greed Mode or Greedier Mode aside from the Soul Hearts granted upon pickup; champions still never drop anything.
• Because of how the item works in the priorities listed above, this item is not recommended for The Lost (except in combination with Immaculate Conception) as he is always considered to be at half a Soul Heart, and all drops from champions are replaced with Soul Hearts.
  • The Lost and Tainted Lost ignore both rules for Soul Heart generation. This prevents the item from generating mostly useless Soul Hearts.
• When playing as The Forgotten, the priority of the drops is based on the active form's health: for example, if The Forgotten has half a red heart or less, but The Soul was active right before the pickup drop and it had more than 2 soul hearts, the Glyph will skip over the full red heart drops to the next condition. Also if The Forgotten is full on pickups and health, has a trinket but has less than 6 bone hearts, the Glyph will always drop soul hearts unless The Soul is active at the moment of the drop.
• When playing as Jacob and Esau / Tainted Lazarus, the priority of the drops is based on the health of the character that has the Glyph.
• When playing as Tainted Lazarus, the room drop will be modified when the character switches to the character that has the item on room clear.
• Chest drops override the Glyph of Balance.
• Empty room drops are replaced by Glyph of Balance drops, with the exception of heart drops in hard mode, which have a separate chance of being replaced with an empty drop.
• When playing as characters incapable of having red heart containers such as ???, the Glyph will skip soul heart and red heart generation.
  • It is still possible to get hearts if none of the other conditions are true.

Interactions

• Options?: Only one of the options will be modified by the Glyph.
• Perfection: Chest spawns are prioritized over Glyph of Balance, meaning it will be very hard to use the Glyph effectively.

In-game Footage

The Binding of Isaac: Rebirth
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