Because of how the item works in the priorities listed above, this item is useless for The Lost (except in combination with Immaculate Conception) as he is always considered to be at half a Soul Heart, and all champion drops are replaced with Soul Hearts.
The Glyph has no effect in Greed Mode or Greedier Mode; champions still never drop anything.
This page was last edited on 4 April 2021, at 18:38.
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