Glaucoma is a passive item added in The Binding of Isaac: Afterbirth †.


  • Adds a chance to shoot concussive tears, causing enemies to walk around randomly.
    • The confusion caused by Glaucoma tears is effectively permanent for normal enemies, and a very long duration compared to most status effects for bosses.
  • Makes the screen darker.


  • Not affected by Luck.


In-game Footage


  • Glaucoma is a group of eye diseases that result in damage to the optic nerve and vision loss.
  • This item bears a strong resemblance to Collectible Cain's Other Eye icon.png Cain's Other Eye.


PC Dlc r indicator.png Z0P0 QZGH (Treasure room adjacent to spawn)

Switch Greedier Mode Indicator.png LG8R 219Y (First Golden Treasure Room)

Switch HardIndicator.png G9ZE YETP (First Treasure Room, Curse of the Unknown)

SmallIsaac.png The Binding of Isaac: Rebirth SmallIsaac.png
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Character Isaac appearance.png Characters MainPageBabies.png Co-op MainPageItems Small.png Items Collectible Isaac's Tears icon.png Item pools MainPageMonsters.png Monsters MainPageObjects.png Objects
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