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Added in Afterbirth †

Glaucoma is a passive item added in The Binding of Isaac: Afterbirth †.

Effects[edit | edit source]

  • Adds a chance to shoot concussive tears, causing enemies to walk around randomly.
    • The confusion caused by Glaucoma tears is effectively permanent for normal enemies, and a very long duration compared to most status effects for bosses.
  • Makes the screen darker.

Notes[edit | edit source]

  • Not affected by Luck.

Synergies[edit | edit source]

  • 15►Black Candle Black Candle : Removes the darker screen caused by Glaucoma.
  • 15►Night Light Night Light: Removes the darker screen caused by Glaucoma.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Glaucoma is a group of eye diseases that result in damage to the optic nerve and vision loss.
  • This item bears a strong resemblance to 15►Cain's Other Eye Cain's Other Eye.

Seeds[edit | edit source]

PC Added in Repentance Z0P0 QZGH (Treasure room adjacent to spawn)

Switch Greedier mode only LG8R 219Y (First Golden Treasure Room)

Switch Hard mode only G9ZE YETP (First Treasure Room, Curse of the Unknown)

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