Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki
Glass   Cannon
Character Judas appearance.png
Full red heart
Table dividing line 1.png
Challenge Number
Starting Items
15►Epic Fetus Epic Fetus
15►Loki's Horns Loki's Horns
Available Rooms
Item Pool Treasure Room.png: no          Item Pool Shop.png: yes
Boss Satan.png
Rules Card Rules Card
Unlock Method

Glass Cannon Beat The Family Man (challenge #19) and defeat Lokii

Disambig.png This article is about the challenge. For the item, see Glass Cannon.

Glass Cannon is challenge #11. Start off as Judas with 15►Epic Fetus Epic Fetus and 15►Loki's Horns Loki's Horns. The goal is to defeat Satan. This challenge is unlocked by unlocking Epic Fetus and Loki's Horns, which requires completing challenge #19, The Family Man and defeating Lokii, respectively.


  • Starting the game with only one heart container. This means that without acquiring additional heart containers, soul hearts, or black hearts, doing any self-damage will instantly kill Judas.
  • However, with the ability to access all Secret Rooms, Super Secret Rooms, and Crawl Spaces on all floors, as well as free access to all the pickups that tinted rocks, urns, mushrooms, skulls, and polyps provide, experienced players can get very easy runs.


  • Epic Fetus is an incredibly powerful offensive item, so primarily focus on acquiring health upgrades and defensive items such as Pretty Fly (from a pill or Slot Machine), 15►Sacrificial Dagger Sacrificial Dagger, 15►Cube of Meat Cube of Meat, and 15►Ball of Bandages Ball of Bandages. 15►Demon Baby Demon Baby and 15►Rotten Baby Rotten Baby can be helpful as well, as they do not require aiming to do damage.
  • 15►Pyromaniac Pyromaniac or Added in Afterbirth15►Host Hat Host Hat are highly useful as they prevent self-damage.
  • 15►Strange Attractor Strange Attractor is highly effective, because most enemies and some bosses will be pulled towards the missiles instead of targeting the player. However, finding it is extremely unlikely because it is only found in the Treasure Room item pool.
  • Destroying all rocks and destructible objects on every floor, as well as accessing both Secret Rooms on each floor, is a vital aspect to completing the challenge easily.
  • Loki's Horns are difficult to utilize effectively with Epic Fetus. However, the extra crosshairs can move through walls and are always the same distance from the character as the main crosshair, so pretend that they are not there, and just avoid taking damage from the main crosshair.
  • Added in Afterbirth 15►Brimstone Brimstone will make this challenge incredibly easy. It synergizes with Epic Fetus, firing 10 blood lasers. If Loki's horns activate, the 40 lasers will usually cover an entire standard size room. With 15►20/20 20/20 or the Bookworm transformation, the 80 lasers will destroy most bosses in one shot
  • Added in Repentance15►Spirit Sword Spirit Sword overrides Epic Fetus, arguably making the challenge easier by removing any chance of self harm or need to aim Epic Fetus missiles.



  • A "glass cannon" is a term used for someone or something that deals high damage but can't take much damage.

MainPageChallenges.png Challenges MainPageChallenges.png

1. Pitch Black 2. High Brow 3. Head Trauma 4. Darkness Falls 5. The Tank 6. Solar System 7. Suicide King
8. Cat Got Your Tongue 9. Demo Man 10. Cursed! 11. Glass Cannon 12. When Life Gives You Lemons 13. Beans! 14. It's in the Cards
15. Slow Roll 16. Computer Savvy 17. Waka Waka 18. The Host 19. The Family Man 20. Purist
21. XXXXXXXXL 22. SPEED! 23. Blue Bomber 24. PAY TO PLAY 25. Have a Heart 26. I RULE! 27. BRAINS!
28. PRIDE DAY! 29. Onan's Streak 30. The Guardian
Afterbirth †
31. Backasswards 32. Aprils Fool 33. Pokey Mans 34. Ultra Hard 35. Pong
36. Scat Man 37. Bloody Mary 38. Baptism by Fire 39. Isaac's Awakening 40. Seeing Double 41. Pica Run 42. Hot Potato
43. Cantripped! 44. Red Redemption 45. DELETE THIS
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets