Binding of Isaac: Rebirth Wiki
Glass   Cannon
Character Judas appearance.png
Full red heart
Table dividing line 1.png
Challenge Number
Starting Items
Epic Fetus Epic Fetus
Loki's Horns Loki's Horns
Available Rooms
Item Pool Treasure Room.png: no          Item Pool Shop.png: yes
Boss Satan portrait.png
Rules Card Rules Card
Unlock Method

Glass Cannon Beat The Family Man (challenge #19) and defeat Lokii

Disambig.png This article is about the challenge. For the item, see Glass Cannon.

Glass Cannon is challenge #11. Start off as Judas Judas with Epic Fetus Epic Fetus and Loki's Horns Loki's Horns. The goal is to defeat Satan Satan. This challenge is unlocked by unlocking Epic Fetus and Loki's Horns, which requires completing The Family Man (challenge #19) and defeating Lokii Lokii, respectively.


  • Starting the game with only one heart container. This means that without acquiring additional heart containers, Soul Heart Soul Hearts, or Black Heart Black Hearts, doing any self-damage will instantly kill Judas.
  • However, with the ability to access all Secret Room Secret Rooms, Super Secret Room Super Secret Rooms, and Crawl Space Crawl Spaces on all floors, as well as free access to all the pickups that tinted rocks, urns, mushrooms, skulls, and polyps provide, experienced players can get very easy runs.


  • Epic Fetus is an incredibly powerful offensive item, so primarily focus on acquiring health upgrades and defensive items such as Pretty Fly (from a pill or Slot Machine.png Slot Machine), Sacrificial Dagger Sacrificial Dagger, Cube of Meat Cube of Meat, and Ball of Bandages Ball of Bandages. Demon Baby Demon Baby and Rotten Baby Rotten Baby can be helpful as well, as they do not require aiming to do damage.
  • Pyromaniac Pyromaniac or Added in AfterbirthHost Hat Host Hat are highly useful as they prevent self-damage.
  • Strange Attractor Strange Attractor is highly effective, because most enemies and some bosses will be pulled towards the missiles instead of targeting the player. However, finding it is extremely unlikely because it is only found in the Treasure Room item pool.
  • Destroying all rocks and destructible objects on every floor, as well as accessing both Secret Rooms on each floor, is a vital aspect to completing the challenge easily.
  • Loki's Horns are difficult to utilize effectively with Epic Fetus. However, the extra crosshairs can move through walls and are always the same distance from the character as the main crosshair, so pretend that they are not there, and just avoid taking damage from the main crosshair.
  • Added in Afterbirth Brimstone Brimstone will make this challenge incredibly easy. It synergizes with Epic Fetus, firing 10 blood lasers. If Loki's horns activate, the 40 lasers will usually cover an entire standard size room. With 20/20 20/20 or the Added in Afterbirth †Bookworm Bookworm transformation, the 80 lasers will destroy most bosses in one shot
  • Added in RepentanceSpirit Sword Spirit Sword overrides Epic Fetus, arguably making the challenge easier by removing any chance of self harm or need to aim Epic Fetus missiles.


  • Rules Card
    Rules Card - Complete Glass Cannon (challenge #11).


  • A "glass cannon" is a term used for someone or something that deals high damage but can't take much damage.