Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Afterbirth
Disambig.png This article is about the item. For the challenge, see Glass Cannon (Challenge).

Glass Cannon is an activated item added in The Binding of Isaac: Afterbirth.


  • Fires a single high-damage piercing tear which can travel over obstacles.
    • The damage dealt by this tear is ten times Isaac's damage, plus a flat 10 damage.
    • The shot has an additional 1.5x size multiplier on top of damage-increased size.
  • Removed in Repentance Sets Isaac's health to half a heart with each use (half a Soul Heart if these are present but there are no Red Heart containers). This also removes any other Soul or Black Hearts, but not Eternal Hearts.
    • Added in Afterbirth † / Removed in Repentance If Isaac has no Red Hearts and at least one Bone Heart, only an empty Bone Heart remains.
  • Added in Repentance Upon taking damage, this item turns into Added in RepentanceBroken Glass Cannon Broken Glass Cannon, and Isaac will lose an additional 2 hearts of health on top of the damage he already took. Isaac gains 1.5 range and leaves a trail of red creep behind him, identical to the effects of Anemic Anemic for the rest of the current room.
    • If the damage from breaking Glass Cannon would result in death, Isaac will remain at half a heart, gaining half a soul heart if necessary. This does not apply if the damage Isaac took would be lethal before the extra damage is taken.


  • The item recharges actively after use, similar to items like The Boomerang The Boomerang, allowing repeated usage within the same room.
  • Shooting the Glass Cannon gives a slight knockback effect to Isaac, which can be dangerous in rooms with obstacles like spikes or Fire Places.


  • Chocolate Milk Chocolate Milk: The current charge of Chocolate Milk affects Glass Cannon.
  • Added in Afterbirth †Compound Fracture Compound Fracture/Cricket's Body Cricket's Body/The Parasite The Parasite: Tears fired by Glass Cannon will split.
  • Godhead Godhead: Creates a giant aura around Glass Cannon tears that almost fills up normal sized rooms.
  • Added in Afterbirth †Lachryphagy Lachryphagy: Glass Cannon will fire giant Lachryphagy tears. Tears are harder to feed as they will burst very quickly but they can be fed if you fire tears beforehand and then fire Glass Cannon into those tears.
  • Multidimensional Baby Multidimensional Baby: The Glass Cannon tears will be doubled by Multidimensional Baby.
  • Mysterious Liquid Mysterious Liquid: Creates a large pool of creep when tears land.
  • Tiny Planet Tiny Planet: Tears produced by Glass Cannon will orbit Isaac.


  • Removed in Afterbirth †9 Volt 9 Volt, Removed in Repentance 20/20 20/20, Anti-Gravity Anti-Gravity,Car Battery Car Battery, The Inner Eye The Inner Eye, Mutant Spider Mutant Spider, Brimstone Brimstone, Dr. Fetus Dr. Fetus, Epic Fetus Epic Fetus, The Ludovico Technique The Ludovico Technique, Marked Marked, Mom's Knife Mom's Knife, Monstro's Lung Monstro's Lung, Technology Technology, and Tech X Tech X: No effect, Glass Cannon fires a normal tear.
    • Added in Afterbirth †9 Volt 9 Volt: Reduces charge time to 2 seconds.
    • Added in Repentance 20/20 20/20: Gives a 25% damage down, hurting Glass Cannon's performance.
  • Added in RepentanceBook of Virtues Book of Virtues: Spawns white wisps on the middle ring. The wisps shatter in one hit and their tears deal 8 damage per shot, but if one of the wisps is destroyed, all the others are also destroyed. Does not affect wisps other than ones made by this item. Despite Glass Cannon having a timed charge, the wisps persist between rooms.
  • Holy Mantle Holy Mantle: Doesn't prevent damage done by Glass Cannon, but will protect against other types of damage.
  • Removed in Repentance Ipecac Ipecac: As the Glass Cannon tears are so large, even a modest damage increase or a single tear size increasing item is likely to render the tear unable to damage enemies, their explosions too far from them.
  • Added in RepentancePluto Pluto: Allows Isaac to cross small gaps using the knockback of Glass Cannon.
  • Soy Milk Soy Milk: Reduces damage of shots, no effect on charge time.
  • Added in Afterbirth †Trisagion Trisagion: Fires normal Trisagion beams that do not have increased damage.
  • Added in Repentance The Wafer The Wafer: Doesn't reduce the damage taken while Glass Cannon is held.

In-game Footage[]


  • Glass Cannon is a term used in video games for a character or entity that deals high amounts of damage but has very low defense.


PC 9BJ3 WWHL (First floor Treasure Room, north of spawn)

Switch Greedier mode only JAWB DBJ6 (First Golden Treasure Room)

PS4 MAYW FFY4 (First Treasure Room, west of spawn)


Bug Bug! Removed in Repentance Glass Cannon can be used to steal Devil Room items by using it to set your health to Removed in Afterbirth † half of a Soul Heart or Added in Afterbirth † no health at all before you die. In the latter case, picking up any item that isn't a health upgrade will kill Isaac.
Bug Bug! Added in Repentance If Tainted Forgotten Tainted Forgotten takes damage with the cannon held above his head, he will be unable to fire and unable to attack. Exiting and continuing will fix this.