- Familiars that normally follow Isaac orbit around him instead.
- Familiars that do not normally block shots will not block shots when converted to orbitals.
- Child Leash: Familiars will orbit much closer to Isaac.
- King Baby: Familiars will orbit King Baby at all times instead of Isaac, even while not firing. King Baby itself is unaffected.
- Best Bud / Distant Admiration / Forever Alone / Friend Zone: Will not orbit closer to Isaac.
- Smart Fly: Will still leave Isaac when he is damaged.
- Spin to Win: Familiars made into orbitals by Friendship Necklace can deal contact damage while Spin to Win is active.
|The Binding of Isaac: Rebirth|
|Achievements||Attributes||Bosses||Cards and Runes||Challenges||Chapters|