Flight is an ability that can be gained by Isaac upon pick up of various items. When Isaac has flight, he can pass over all obstacles, including rocks, poop, and pits, and won't be damaged by hazards such as creep or spikes (except Sacrifice Room spikes). He can still be damaged by Fire Places and spike blocks. , Azazel , The Lost , The Soul , and Tainted Lost start with the ability to fly.
Activated Collectibles that Grant Flight [ ]
Flight + dash attack
flight and increases speed to 1.5 whether or not it has charges. Upon use, Isaac charges in the direction the pony is facing, giving invincibility during the charge and dealing 40 damage. Now deals 4 times Isaac's damage, plus a flat 28 damage.
On use, Isaac gains
flight for the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but kills Isaac when used on Satan.
The Pinking Shears
Cut and run
flight for the current room, while turning Isaac's body into a fast, high damage familiar.
Flight + holy death
flight and increases speed to 1.5. Upon use, Isaac charges in the direction the pony is facing, giving invulnerability during the charge and dealing 40 damage while also casting the effect of Crack the Sky.
Swaps between the current character and Esau Jr., who has +2 flat
damage and flight. Characters have independent items and health. Dying as either character ends the run.
Note: The Pony and White Pony passively grant flight while they are in Isaac's possession.
Passive Collectibles that Grant Flight [ ]
Flight + spectral tears
spectral tears and flight.
flight and one Eternal Heart.
Flight + HP up
flight and one Red Heart container.
Lord of the Pit
flight and +0.3 speed.
Spirit of the Night
spectral tears and flight.
We all float down here...
I reward an empty vessel
Black Hearts. While Isaac has no red hearts, grants flight and periodically grants an invincibility shield for a few seconds.
The true out-of-body experience!
Causes Isaac to turn into a ghost if he gets hit while in an uncleared room, giving him
flight and spectral tears and blocking the next hit he takes.
flight, +0.1 speed, +2 damage, and the effect. Grants enough Holy Mantle health to have 6 full hearts, if possible. Automatically given to Isaac after defeating Dogma.
Awaken your faith
flight and two soul hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser.
death, Isaac's ghost is chained to his dead body and he can continue to fight with 1/2 of a heart, returning to life after 10 seconds. After it activates, it must be recharged by picking up a soul heart.
Trinkets that Grant Flight [ ]
They are growing...
Upon killing an enemy, has a chance to grant flight for the rest of the room.
Unleash your inner demon
When clearing a room, adds a chance to turn into Azazel until clearing another.
Other Ways to Gain Flight [ ]